Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ADAMTS1
  • Mouse genes Adamts1
  • Rat genes Adamts1
  • Zfish genes adamts1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Adamts1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008201	heparin binding	Adamts1	IDA		Mouse	PMID:8995297
Molecular Function	GO:0008201	heparin binding	Adamts1	IDA		Mouse	PMID:9593739
Molecular Function	GO:0004222	metalloendopeptidase activity	ADAMTS1	IDA		Human	PMID:11278559
Molecular Function	GO:0004222	metalloendopeptidase activity	ADAMTS1	IDA		Human	PMID:25122765
Molecular Function	GO:0004222	metalloendopeptidase activity	Adamts1	IMP	MGI:MGI:3609982	Mouse	PMID:16061471
Molecular Function	GO:0004222	metalloendopeptidase activity	Adamts1	IDA		Mouse	PMID:16061471
Molecular Function	GO:0005515	protein binding	ADAMTS1	IPI	UniProtKB:P60410	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ADAMTS1	IPI	UniProtKB:Q6A162	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ADAMTS1	IPI	UniProtKB:O00233	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Adamts1	IPI	PR:Q08879	Mouse	PMID:16061471
Cellular Component	GO:0005604	basement membrane	Adamts1	IDA		Mouse	PMID:16061471
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ADAMTS1	HDA		Human	PMID:28327460
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Adamts1	IDA		Rat	PMID:15777654|RGD:9681749
Cellular Component	GO:0031410	cytoplasmic vesicle	Adamts1	IDA		Mouse	PMID:12907688
Cellular Component	GO:0031012	extracellular matrix	Adamts1	IDA		Mouse	PMID:9593739
Cellular Component	GO:0031012	extracellular matrix	Adamts1	IDA		Mouse	PMID:12907688
Biological Process	GO:0071374	cellular response to parathyroid hormone stimulus	Adamts1	IEP		Rat	PMID:11108265|RGD:9681746
Biological Process	GO:0071380	cellular response to prostaglandin E stimulus	Adamts1	IEP		Rat	PMID:11108265|RGD:9681746
Biological Process	GO:0071305	cellular response to vitamin D	Adamts1	IEP		Rat	PMID:11108265|RGD:9681746
Biological Process	GO:0060347	heart trabecula formation	Adamts1	IMP	MGI:MGI:3609982	Mouse	PMID:18267097
Biological Process	GO:0001822	kidney development	Adamts1	IMP	MGI:MGI:3609982	Mouse	PMID:16061471
Biological Process	GO:0001822	kidney development	Adamts1	IMP	MGI:MGI:3574351	Mouse	PMID:14668204
Biological Process	GO:0016525	negative regulation of angiogenesis	ADAMTS1	IDA		Human	PMID:10438512
Biological Process	GO:0030728	ovulation	Adamts1	IEP		Rat	PMID:10727282|RGD:631923
Biological Process	GO:0001542	ovulation from ovarian follicle	Adamts1	IMP	MGI:MGI:3574351	Mouse	PMID:14668204
Biological Process	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	ADAMTS1	IGI	RNAcentral:URS00003A19A3_9606	Human	PMID:28890348
Biological Process	GO:0010976	positive regulation of neuron projection development	Adamts1	IMP		Rat	PMID:23825416|RGD:8655547
Biological Process	GO:1904754	positive regulation of vascular associated smooth muscle cell migration	ADAMTS1	IGI	RNAcentral:URS00003A19A3_9606	Human	PMID:28890348
Biological Process	GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	ADAMTS1	IGI	RNAcentral:URS00003A19A3_9606	Human	PMID:28890348
Biological Process	GO:0044691	tooth eruption	Adamts1	IEP		Rat	PMID:16200461|RGD:9684848

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern