Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ADAMTSL2
  • Mouse genes Adamtsl2
  • Rat genes Adamtsl2
  • Zfish genes adamtsl2,si:ch211-267e7.3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Adamtsl2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050436	microfibril binding	Adamtsl2	IPI	PR:Q61555	Mouse	PMID:25762570
Molecular Function	GO:0050436	microfibril binding	Adamtsl2	IPI	PR:Q61554	Mouse	PMID:25762570
Molecular Function	GO:0005515	protein binding	ADAMTSL2	IPI	UniProtKB:Q14766	Human	PMID:18677313
Molecular Function	GO:0005515	protein binding	Adamtsl2	IPI	UniProtKB:P28301|UniProtKB:P58215	Mouse	MGI:MGI:6313570|PMID:29758265
Cellular Component	GO:0031012	extracellular matrix	Adamtsl2	IDA		Mouse	PMID:17509843
Cellular Component	GO:0005576	extracellular region	Adamtsl2	IDA		Mouse	PMID:17509843
Biological Process	GO:0030198	extracellular matrix organization	Adamtsl2	IMP		Mouse	PMID:25762570
Biological Process	GO:0060481	lobar bronchus epithelium development	Adamtsl2	IMP		Mouse	PMID:25762570
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	ADAMTSL2	IMP		Human	PMID:18677313
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	Adamtsl2	IMP		Mouse	PMID:25762570

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern