Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ADAP1
  • Mouse genes Adap1
  • Rat genes Adap1
  • Zfish genes zgc:92360
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Adap1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005096	GTPase activator activity	ADAP1	IDA		Human	PMID:10333475
Molecular Function	GO:0005096	GTPase activator activity	ADAP1	IDA		Human	PMID:10448098
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	Adap1	IDA		Rat	PMID:9748531|RGD:632412
Molecular Function	GO:0005515	protein binding	ADAP1	IPI	UniProtKB:P17252	Human	PMID:12893243
Molecular Function	GO:0005515	protein binding	ADAP1	IPI	UniProtKB:P41743	Human	PMID:12893243
Molecular Function	GO:0005515	protein binding	ADAP1	IPI	UniProtKB:Q05513	Human	PMID:12893243
Molecular Function	GO:0005515	protein binding	ADAP1	IPI	UniProtKB:Q15139	Human	PMID:12893243
Molecular Function	GO:0005515	protein binding	ADAP1	IPI	UniProtKB:Q9NQT8	Human	PMID:21057110
Molecular Function	GO:0005515	protein binding	ADAP1	IPI	UniProtKB:Q08379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ADAP1	IPI	UniProtKB:Q92997	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ADAP1	IPI	UniProtKB:Q9H190	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ADAP1	IPI	UniProtKB:Q9H8W4	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	ADAP1	IDA		Human	PMID:10333475
Cellular Component	GO:0005737	cytoplasm	ADAP1	IDA		Human	PMID:10448098
Cellular Component	GO:0005829	cytosol	ADAP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ADAP1	IDA		Human	PMID:10333475
Cellular Component	GO:0005634	nucleus	ADAP1	IDA		Human	PMID:10448098
Cellular Component	GO:0005886	plasma membrane	ADAP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ADAP1	IDA		Human	PMID:10333475
Cellular Component	GO:0005886	plasma membrane	ADAP1	IDA		Human	PMID:10448098
Biological Process	GO:0043087	regulation of GTPase activity	ADAP1	IMP		Human	PMID:10333475

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern