Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Adcyap1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ADCYAP1
- Mouse genes Adcyap1
- Rat genes Adcyap1
- Zfish genes adcyap1a,adcyap1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Adcyap1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005184	neuropeptide hormone activity	ADCYAP1	IDA		Human	PMID:23800469
Molecular Function	GO:0005184	neuropeptide hormone activity	Adcyap1	IDA		Rat	PMID:23800469\|RGD:8554519
Molecular Function	GO:0051428	peptide hormone receptor binding	ADCYAP1	IDA		Human	PMID:11175907
Molecular Function	GO:0051428	peptide hormone receptor binding	ADCYAP1	IPI	UniProtKB:P41586	Human	PMID:17470806
Molecular Function	GO:0016521	pituitary adenylate cyclase activating polypeptide activity	ADCYAP1	IDA		Human	PMID:9603988
Molecular Function	GO:0016521	pituitary adenylate cyclase activating polypeptide activity	Adcyap1	IDA		Mouse	MGI:MGI:5318038\|PMID:9603988
Molecular Function	GO:0016521	pituitary adenylate cyclase activating polypeptide activity	Adcyap1	IDA		Rat	PMID:9603988\|RGD:8554017
Molecular Function	GO:0031858	pituitary adenylate cyclase-activating polypeptide receptor binding	Adcyap1	IDA		Rat	PMID:8238511\|RGD:2325315
Molecular Function	GO:0005515	protein binding	ADCYAP1	IPI	UniProtKB:P41586-3	Human	PMID:17470806
Molecular Function	GO:0005515	protein binding	ADCYAP1	IPI	UniProtKB:P10909	Human	PMID:25451228
Molecular Function	GO:0005515	protein binding	ADCYAP1	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005102	signaling receptor binding	ADCYAP1	IPI	UniProtKB:Q02643	Human	PMID:7680413
Cellular Component	GO:0005615	extracellular space	Adcyap1	IDA		Rat	PMID:17698245\|RGD:2325282
Cellular Component	GO:0043195	terminal bouton	Adcyap1	IDA		Rat	PMID:9792613\|RGD:2312463
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ADCYAP1	IDA		Human	PMID:9603988
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	Adcyap1	IDA		Mouse	MGI:MGI:5318038\|PMID:9603988
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	Adcyap1	IDA		Rat	PMID:18541665\|RGD:2325271
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	Adcyap1	IDA		Rat	PMID:9603988\|RGD:8554017
Biological Process	GO:0046034	ATP metabolic process	Adcyap1	IDA		Rat	PMID:18563302\|RGD:2315964
Biological Process	GO:0001662	behavioral fear response	Adcyap1	IDA		Rat	PMID:17641738\|RGD:2325286
Biological Process	GO:0007420	brain development	adcyap1a	IMP	ZFIN:ZDB-MRPHLNO-061208-2	Zfish	PMID:16888233
Biological Process	GO:0007420	brain development	adcyap1a	IMP	ZFIN:ZDB-MRPHLNO-061208-1	Zfish	PMID:16888233
Biological Process	GO:0007420	brain development	adcyap1b	IMP	ZFIN:ZDB-MRPHLNO-061208-4	Zfish	PMID:16888233
Biological Process	GO:0007420	brain development	adcyap1b	IMP	ZFIN:ZDB-MRPHLNO-061208-3	Zfish	PMID:16888233
Biological Process	GO:0043010	camera-type eye development	adcyap1a	IMP	ZFIN:ZDB-MRPHLNO-061208-1	Zfish	PMID:16888233
Biological Process	GO:0043010	camera-type eye development	adcyap1b	IMP	ZFIN:ZDB-MRPHLNO-061208-3	Zfish	PMID:16888233
Biological Process	GO:0019933	cAMP-mediated signaling	ADCYAP1	IMP		Human	PMID:23800469
Biological Process	GO:0019933	cAMP-mediated signaling	Adcyap1	IMP		Rat	PMID:23800469\|RGD:8554519
Biological Process	GO:0071385	cellular response to glucocorticoid stimulus	Adcyap1	IEP		Rat	PMID:17884294\|RGD:2325276
Biological Process	GO:0001821	histamine secretion	Adcyap1	IDA		Rat	PMID:17660849\|RGD:2325283
Biological Process	GO:0030073	insulin secretion	Adcyap1	IDA		Mouse	MGI:MGI:5525944\|PMID:23913443
Biological Process	GO:0002865	negative regulation of acute inflammatory response to antigenic stimulus	Adcyap1	IDA		Rat	PMID:17698245\|RGD:2325282
Biological Process	GO:0002878	negative regulation of acute inflammatory response to non-antigenic stimulus	Adcyap1	IDA		Rat	PMID:20229361\|RGD:2325270
Biological Process	GO:0045786	negative regulation of cell cycle	Adcyap1	IDA		Mouse	PMID:12417650
Biological Process	GO:0060253	negative regulation of glial cell proliferation	Adcyap1	IDA		Rat	PMID:15870074\|RGD:2325307
Biological Process	GO:0034260	negative regulation of GTPase activity	Adcyap1	IDA		Rat	PMID:15870074\|RGD:2325307
Biological Process	GO:0010656	negative regulation of muscle cell apoptotic process	Adcyap1	IDA		Rat	PMID:16891268\|RGD:2325292
Biological Process	GO:0043267	negative regulation of potassium ion transport	Adcyap1	IDA		Rat	PMID:17498241\|RGD:2325289
Biological Process	GO:0031175	neuron projection development	ADCYAP1	IDA		Human	PMID:23800469
Biological Process	GO:0031175	neuron projection development	Adcyap1	IDA		Rat	PMID:23800469\|RGD:8554519
Biological Process	GO:0007218	neuropeptide signaling pathway	ADCYAP1	IDA		Human	PMID:23800469
Biological Process	GO:0007218	neuropeptide signaling pathway	Adcyap1	IDA		Rat	PMID:23800469\|RGD:8554519
Biological Process	GO:0001541	ovarian follicle development	Adcyap1	IDA		Rat	PMID:20138961\|RGD:2325269
Biological Process	GO:0021983	pituitary gland development	Adcyap1	IEP		Rat	PMID:18160680\|RGD:2325274
Biological Process	GO:0043950	positive regulation of cAMP-mediated signaling	Adcyap1	IDA		Rat	PMID:17901570\|RGD:2325275
Biological Process	GO:0008284	positive regulation of cell population proliferation	Adcyap1	IDA		Rat	PMID:15968088\|RGD:2315981
Biological Process	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production	ADCYAP1	IDA		Human	PMID:24696163
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Adcyap1	IMP		Mouse	MGI:MGI:2388256\|PMID:12239106
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Adcyap1	IDA		Rat	PMID:18198219\|RGD:2325273
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ADCYAP1	IDA		Human	PMID:23800469
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Adcyap1	IDA		Rat	PMID:23800469\|RGD:8554519
Biological Process	GO:0010628	positive regulation of gene expression	Adcyap1	IDA		Mouse	PMID:23913443
Biological Process	GO:0060124	positive regulation of growth hormone secretion	Adcyap1	IDA		Rat	PMID:18198219\|RGD:2325273
Biological Process	GO:0043547	positive regulation of GTPase activity	ADCYAP1	IDA		Human	PMID:23800469
Biological Process	GO:0043547	positive regulation of GTPase activity	Adcyap1	IDA		Rat	PMID:23800469\|RGD:8554519
Biological Process	GO:0032755	positive regulation of interleukin-6 production	Adcyap1	IDA		Rat	PMID:16888221\|RGD:2325294
Biological Process	GO:0010976	positive regulation of neuron projection development	Adcyap1	IDA		Rat	PMID:18541665\|RGD:2325271
Biological Process	GO:0010976	positive regulation of neuron projection development	Adcyap1	IGI	UniProtKB:P42930	Rat	PMID:18541665\|RGD:2325271
Biological Process	GO:0010976	positive regulation of neuron projection development	Adcyap1	IGI	UniProtKB:Q5BJQ5	Rat	PMID:18541665\|RGD:2325271
Biological Process	GO:0045860	positive regulation of protein kinase activity	ADCYAP1	IDA		Human	PMID:23800469
Biological Process	GO:0045860	positive regulation of protein kinase activity	Adcyap1	IDA		Rat	PMID:23800469\|RGD:8554519
Biological Process	GO:0090274	positive regulation of somatostatin secretion	Adcyap1	IDA		Rat	PMID:17660849\|RGD:2325283
Biological Process	GO:0051968	positive regulation of synaptic transmission, glutamatergic	Adcyap1	IDA		Rat	PMID:16483357\|RGD:2325299
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ADCYAP1	IDA		Human	PMID:23800469
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Adcyap1	IDA		Rat	PMID:23800469\|RGD:8554519
Biological Process	GO:0008277	regulation of G protein-coupled receptor signaling pathway	ADCYAP1	IDA		Human	PMID:11175907
Biological Process	GO:0070445	regulation of oligodendrocyte progenitor proliferation	Adcyap1	IDA		Rat	PMID:16989910\|RGD:2325291
Biological Process	GO:0060078	regulation of postsynaptic membrane potential	Adcyap1	IDA		Rat	PMID:18727050\|RGD:2325264
Biological Process	GO:0032880	regulation of protein localization	ADCYAP1	IDA		Human	PMID:9603988
Biological Process	GO:0032880	regulation of protein localization	Adcyap1	IDA		Mouse	MGI:MGI:5318038\|PMID:9603988
Biological Process	GO:0032880	regulation of protein localization	Adcyap1	IDA		Rat	PMID:9603988\|RGD:8554017
Biological Process	GO:0001932	regulation of protein phosphorylation	Adcyap1	IGI	UniProtKB:Q5BJQ5	Rat	PMID:18541665\|RGD:2325271
Biological Process	GO:0045471	response to ethanol	Adcyap1	IEP		Rat	PMID:16820725\|RGD:2325297
Biological Process	GO:0042594	response to starvation	Adcyap1	IEP		Rat	PMID:16888191\|RGD:2325296
Biological Process	GO:0019233	sensory perception of pain	Adcyap1	IDA		Rat	PMID:19091468\|RGD:2325267
Biological Process	GO:0042311	vasodilation	Adcyap1	IDA		Rat	PMID:19220306\|RGD:2325268

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.