Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ADCYAP1R1
  • Mouse genes Adcyap1r1
  • Rat genes Adcyap1r1
  • Zfish genes adcyap1r1a,adcyap1r1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Adcyap1r1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008179	adenylate cyclase binding	Adcyap1r1	IDA		Rat	PMID:17680996|RGD:2315969
Molecular Function	GO:0042923	neuropeptide binding	Adcyap1r1	IDA		Rat	PMID:16905223|RGD:2315974
Molecular Function	GO:0005515	protein binding	ADCYAP1R1	IPI	UniProtKB:P18509	Human	PMID:17470806
Molecular Function	GO:0005515	protein binding	Adcyap1r1	IPI	PR:Q6NSW3	Mouse	PMID:22084075
Molecular Function	GO:0031267	small GTPase binding	Adcyap1r1	IDA		Rat	PMID:11353814|RGD:2315984
Cellular Component	GO:0005923	bicellular tight junction	Adcyap1r1	IDA		Rat	PMID:16626868|RGD:2315976
Cellular Component	GO:0005901	caveola	Adcyap1r1	IDA		Rat	PMID:17680996|RGD:2315969
Cellular Component	GO:0009986	cell surface	Adcyap1r1	IDA		Rat	PMID:15968088|RGD:2315981
Cellular Component	GO:0005737	cytoplasm	Adcyap1r1	IDA		Rat	PMID:16876955|RGD:2315972
Cellular Component	GO:0005768	endosome	Adcyap1r1	IDA		Rat	PMID:19416476|RGD:2315957
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ADCYAP1R1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043005	neuron projection	Adcyap1r1	IDA		Rat	PMID:16876955|RGD:2315972
Cellular Component	GO:0043235	receptor complex	ADCYAP1R1	IDA		Human	PMID:23382219
Cellular Component	GO:0005791	rough endoplasmic reticulum	Adcyap1r1	IDA		Rat	PMID:9464636|RGD:2315987
Biological Process	GO:0007202	activation of phospholipase C activity	Adcyap1r1	IDA		Rat	PMID:8396727|RGD:631732
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	adcyap1r1a	IDA		Zfish	PMID:18757498
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	adcyap1r1a	IDA		Zfish	PMID:15713535
Biological Process	GO:0019933	cAMP-mediated signaling	Adcyap1r1	IDA		Rat	PMID:8396727|RGD:631732
Biological Process	GO:0046545	development of primary female sexual characteristics	Adcyap1r1	IEP		Rat	PMID:17065411|RGD:2315970
Biological Process	GO:0021854	hypothalamus development	adcyap1r1b	IMP	ZFIN:ZDB-MRPHLNO-080414-3	Zfish	PMID:18003738
Biological Process	GO:0033555	multicellular organismal response to stress	Adcyap1r1	IEP		Rat	PMID:19181454|RGD:2315958
Biological Process	GO:1901032	negative regulation of response to reactive oxygen species	Adcyap1r1	IDA		Rat	PMID:16905223|RGD:2315974
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	adcyap1r1a	IDA		Zfish	PMID:15713535
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	adcyap1r1a	IDA		Zfish	PMID:18757498
Biological Process	GO:0010524	positive regulation of calcium ion transport into cytosol	Adcyap1r1	IMP		Rat	PMID:16401644|RGD:2315978
Biological Process	GO:0043950	positive regulation of cAMP-mediated signaling	Adcyap1r1	IDA		Rat	PMID:16905223|RGD:2315974
Biological Process	GO:0060732	positive regulation of inositol phosphate biosynthetic process	Adcyap1r1	IDA		Rat	PMID:8943280|RGD:2315982
Biological Process	GO:0051057	positive regulation of small GTPase mediated signal transduction	Adcyap1r1	IMP		Rat	PMID:18541665|RGD:2325271
Biological Process	GO:0032355	response to estradiol	Adcyap1r1	IEP		Rat	PMID:15976009|RGD:2315980
Biological Process	GO:0045471	response to ethanol	Adcyap1r1	IEP		Rat	PMID:16820708|RGD:2315973
Biological Process	GO:0009410	response to xenobiotic stimulus	Adcyap1r1	IEP		Rat	PMID:18592413|RGD:2315962

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern