Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ADGRE2,ADGRE5
  • Mouse genes Adgre5
  • Rat genes Adgre5
  • Zfish genes adgre5b.2,adgre5b.3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Adgre5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035374	chondroitin sulfate binding	ADGRE2	IMP		Human	PMID:12829604
Molecular Function	GO:0005515	protein binding	ADGRE5	IPI	UniProtKB:P08174	Human	PMID:11297558
Molecular Function	GO:0005515	protein binding	ADGRE5	IPI	UniProtKB:P04216	Human	PMID:22210915
Molecular Function	GO:0005515	protein binding	ADGRE5	IPI	UniProtKB:P08174	Human	PMID:9064337
Molecular Function	GO:0005515	protein binding	ADGRE2	IPI	UniProtKB:Q03591	Human	PMID:31273197
Molecular Function	GO:0005515	protein binding	ADGRE2	IPI	UniProtKB:A1L3X0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ADGRE2	IPI	UniProtKB:O60337	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ADGRE2	IPI	UniProtKB:P43628	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ADGRE2	IPI	UniProtKB:Q13323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ADGRE2	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ADGRE2	IPI	UniProtKB:Q5JX71	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ADGRE2	IPI	UniProtKB:Q6N075	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ADGRE2	IPI	UniProtKB:Q7Z5P4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ADGRE2	IPI	UniProtKB:Q8N4V1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ADGRE2	IPI	UniProtKB:Q8TBB6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ADGRE2	IPI	UniProtKB:Q8WV48	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ADGRE2	IPI	UniProtKB:Q96BA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ADGRE2	IPI	UniProtKB:Q96E29	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ADGRE2	IPI	UniProtKB:Q96HE8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ADGRE2	IPI	UniProtKB:Q96MV1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ADGRE2	IPI	UniProtKB:Q9GZR5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ADGRE2	IPI	UniProtKB:Q9NR31	Human	PMID:32296183
Cellular Component	GO:0009897	external side of plasma membrane	Adgre5	IDA		Mouse	PMID:19299737
Cellular Component	GO:0070062	extracellular exosome	ADGRE5	HDA		Human	PMID:20458337
Cellular Component	GO:0005925	focal adhesion	ADGRE5	HDA		Human	PMID:21423176
Cellular Component	GO:0031256	leading edge membrane	ADGRE2	IDA		Human	PMID:17928360
Cellular Component	GO:0016020	membrane	ADGRE5	HDA		Human	PMID:19946888
Biological Process	GO:0007155	cell adhesion	ADGRE2	IMP		Human	PMID:12829604
Biological Process	GO:0016477	cell migration	ADGRE2	IMP		Human	PMID:17928360
Biological Process	GO:0071621	granulocyte chemotaxis	ADGRE2	IMP		Human	PMID:17928360
Biological Process	GO:0051965	positive regulation of synapse assembly	Adgre5	IDA		Mouse	PMID:24613359
Biological Process	GO:0043304	regulation of mast cell degranulation	ADGRE2	IMP		Human	PMID:26841242

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern