Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ADGRG1
  • Mouse genes Adgrg1
  • Rat genes Adgrg1
  • Zfish genes adgrg1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Adgrg1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005518	collagen binding	Adgrg1	IDA		Mouse	MGI:MGI:5288127|PMID:21768377
Molecular Function	GO:0050840	extracellular matrix binding	Adgrg1	IDA		Mouse	MGI:MGI:3796260|PMID:18509043
Molecular Function	GO:0004930	G protein-coupled receptor activity	Adgrg1	IMP		Mouse	MGI:MGI:5288127|PMID:21768377
Molecular Function	GO:0008201	heparin binding	ADGRG1	IDA		Human	PMID:27068534
Molecular Function	GO:0008201	heparin binding	Adgrg1	IDA		Mouse	MGI:MGI:5780347|PMID:27068534
Molecular Function	GO:0005515	protein binding	ADGRG1	IPI	UniProtKB:P02461	Human	PMID:28258187
Cellular Component	GO:0070062	extracellular exosome	ADGRG1	HDA		Human	PMID:23533145
Cellular Component	GO:0097451	glial limiting end-foot	Adgrg1	IDA		Mouse	MGI:MGI:3796260|PMID:18509043
Biological Process	GO:0001525	angiogenesis	ADGRG1	IDA		Human	PMID:21724588
Biological Process	GO:0007420	brain development	ADGRG1	IMP		Human	PMID:15044805
Biological Process	GO:0007155	cell adhesion	ADGRG1	IDA		Human	PMID:27068534
Biological Process	GO:0016477	cell migration	ADGRG1	IDA		Human	PMID:27068534
Biological Process	GO:0021801	cerebral cortex radial glia-guided migration	Adgrg1	IMP		Mouse	MGI:MGI:3796260|PMID:18509043
Biological Process	GO:0021796	cerebral cortex regionalization	Adgrg1	IMP		Mouse	PMID:24531968
Biological Process	GO:0061484	hematopoietic stem cell homeostasis	Adgrg1	IMP		Mouse	PMID:26880577
Biological Process	GO:0021819	layer formation in cerebral cortex	Adgrg1	IMP		Mouse	MGI:MGI:3796260|PMID:18509043
Biological Process	GO:0048932	myelination of posterior lateral line nerve axons	adgrg1	IGI	ZFIN:ZDB-GENO-180713-3,ZFIN:ZDB-MRPHLNO-060113-1,ZFIN:ZDB-MRPHLNO-060113-3,ZFIN:ZDB-MRPHLNO-060113-4	Zfish	PMID:29367382
Biological Process	GO:0008285	negative regulation of cell population proliferation	ADGRG1	IDA		Human	PMID:16757564
Biological Process	GO:2001223	negative regulation of neuron migration	Adgrg1	IMP		Mouse	MGI:MGI:3796260|PMID:18509043
Biological Process	GO:0061351	neural precursor cell proliferation	Adgrg1	IMP		Mouse	PMID:24531968
Biological Process	GO:0014003	oligodendrocyte development	adgrg1	IGI	ZFIN:ZDB-GENO-160202-2,ZFIN:ZDB-MRPHLNO-060113-1,ZFIN:ZDB-MRPHLNO-060113-3,ZFIN:ZDB-MRPHLNO-060113-4	Zfish	PMID:25607772
Biological Process	GO:0032287	peripheral nervous system myelin maintenance	adgrg1	IMP	ZFIN:ZDB-GENO-180713-2	Zfish	PMID:29367382
Biological Process	GO:0045785	positive regulation of cell adhesion	ADGRG1	IDA		Human	PMID:21349848
Biological Process	GO:2000179	positive regulation of neural precursor cell proliferation	Adgrg1	IMP		Mouse	PMID:24531968
Biological Process	GO:0035025	positive regulation of Rho protein signal transduction	Adgrg1	IMP		Mouse	MGI:MGI:5288127|PMID:21768377
Biological Process	GO:0070528	protein kinase C signaling	ADGRG1	IDA		Human	PMID:21724588
Biological Process	GO:0070445	regulation of oligodendrocyte progenitor proliferation	adgrg1	IMP	ZFIN:ZDB-GENO-160202-2	Zfish	PMID:25607772
Biological Process	GO:0007266	Rho protein signal transduction	ADGRG1	IDA		Human	PMID:21708946
Biological Process	GO:0072520	seminiferous tubule development	Adgrg1	IMP		Mouse	MGI:MGI:4847971|PMID:20981830
Biological Process	GO:0010573	vascular endothelial growth factor production	ADGRG1	IDA		Human	PMID:21724588

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern