Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ADGRL3
  • Mouse genes Adgrl3
  • Rat genes Adgrl3
  • Zfish genes adgrl3.1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Adgrl3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	ADGRL3	IDA		Human	PMID:26235030
Molecular Function	GO:0005509	calcium ion binding	Adgrl3	IDA		Mouse	MGI:MGI:5693672|PMID:26235031
Molecular Function	GO:0005515	protein binding	ADGRL3	IPI	UniProtKB:Q9NZU0	Human	PMID:26235030
Molecular Function	GO:0005515	protein binding	Adgrl3	IPI	UniProtKB:Q8BGT1	Mouse	MGI:MGI:5693672|PMID:26235031
Molecular Function	GO:0005515	protein binding	Adgrl3	IPI	UniProtKB:Q8BLU0	Mouse	MGI:MGI:5688816|PMID:25728924
Molecular Function	GO:0005515	protein binding	Adgrl3	IPI	PR:Q9WTS6	Mouse	PMID:29414938
Cellular Component	GO:0030424	axon	Adgrl3	IDA		Mouse	MGI:MGI:5688833|PMID:22405201
Cellular Component	GO:0005911	cell-cell junction	Adgrl3	IDA		Mouse	MGI:MGI:5688833|PMID:22405201
Cellular Component	GO:0098978	glutamatergic synapse	Adgrl3	IDA		Mouse	PMID:24739570
Cellular Component	GO:0098978	glutamatergic synapse	Adgrl3	IMP		Mouse	PMID:24739570
Cellular Component	GO:0098978	glutamatergic synapse	Adgrl3	IMP		Mouse	PMID:30792275
Cellular Component	GO:0098978	glutamatergic synapse	Adgrl3	IDA		Mouse	PMID:30792275
Cellular Component	GO:0005886	plasma membrane	ADGRL3	IDA		Human	PMID:26235030
Cellular Component	GO:0005886	plasma membrane	Adgrl3	IDA		Mouse	MGI:MGI:5688833|PMID:22405201
Cellular Component	GO:0045211	postsynaptic membrane	Adgrl3	IDA		Mouse	PMID:30792275
Cellular Component	GO:0045211	postsynaptic membrane	Adgrl3	IMP		Mouse	PMID:30792275
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Adgrl3	IMP		Mouse	PMID:30792275
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Adgrl3	IDA		Mouse	PMID:30792275
Biological Process	GO:0007420	brain development	Adgrl3	IEP		Rat	PMID:10964907|RGD:2314401
Biological Process	GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules	ADGRL3	IDA		Human	PMID:26235030
Biological Process	GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules	Adgrl3	IMP		Mouse	MGI:MGI:5688816|PMID:25728924
Biological Process	GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules	Adgrl3	IMP		Mouse	MGI:MGI:5688833|PMID:22405201
Biological Process	GO:0071391	cellular response to estrogen stimulus	adgrl3.1	IDA		Zfish	PMID:18618001
Biological Process	GO:0031987	locomotion involved in locomotory behavior	Adgrl3	IMP		Mouse	MGI:MGI:5430447|PMID:22575564
Biological Process	GO:0007626	locomotory behavior	adgrl3.1	IMP	ZFIN:ZDB-MRPHLNO-130110-3	Zfish	PMID:22508465
Biological Process	GO:0007626	locomotory behavior	adgrl3.1	IMP	ZFIN:ZDB-MRPHLNO-130110-4	Zfish	PMID:22508465
Biological Process	GO:0007626	locomotory behavior	adgrl3.1	IMP	ZFIN:ZDB-MRPHLNO-130110-3	Zfish	PMID:27116683
Biological Process	GO:0098880	maintenance of postsynaptic specialization structure	Adgrl3	IDA		Mouse	PMID:30792275
Biological Process	GO:0098880	maintenance of postsynaptic specialization structure	Adgrl3	IMP		Mouse	PMID:30792275
Biological Process	GO:0001764	neuron migration	Adgrl3	IMP		Mouse	MGI:MGI:5688816|PMID:25728924
Biological Process	GO:0051965	positive regulation of synapse assembly	Adgrl3	IDA		Mouse	PMID:24613359
Biological Process	GO:0042220	response to cocaine	Adgrl3	IMP		Mouse	MGI:MGI:5430447|PMID:22575564
Biological Process	GO:0007416	synapse assembly	Adgrl3	IMP		Mouse	MGI:MGI:5688833|PMID:22405201
Biological Process	GO:0007416	synapse assembly	Adgrl3	IMP		Mouse	PMID:30792275
Biological Process	GO:0007416	synapse assembly	Adgrl3	IDA		Mouse	PMID:30792275
Biological Process	GO:0050808	synapse organization	Adgrl3	IMP		Mouse	PMID:24739570
Biological Process	GO:0050808	synapse organization	Adgrl3	IDA		Mouse	PMID:24739570

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern