Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ADNP
  • Mouse genes Adnp
  • Rat genes Adnp
  • Zfish genes adnpa,adnpb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Adnp

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008013	beta-catenin binding	Adnp	IPI	UniProtKB:Q02248	Mouse	MGI:MGI:6447854|PMID:32533114
Molecular Function	GO:0008013	beta-catenin binding	adnpa	IPI	ZFIN:ZDB-GENO-220308-9	Zfish	PMID:32533114
Molecular Function	GO:0048487	beta-tubulin binding	Adnp	IPI	RGD:628595	Rat	PMID:16893427|RGD:2312776
Molecular Function	GO:0003682	chromatin binding	Adnp	IDA		Mouse	PMID:17222401
Molecular Function	GO:0005507	copper ion binding	Adnp	IDA		Rat	PMID:14706557|RGD:2312790
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Adnp	IDA		Mouse	MGI:MGI:3701370|PMID:17222401
Molecular Function	GO:0042277	peptide binding	Adnp	IDA		Rat	PMID:14706557|RGD:2312790
Molecular Function	GO:0005515	protein binding	ADNP	IPI	UniProtKB:P45973	Human	PMID:20562864
Molecular Function	GO:0005515	protein binding	ADNP	IPI	UniProtKB:P45973	Human	PMID:21888893
Molecular Function	GO:0005515	protein binding	ADNP	IPI	UniProtKB:P83916	Human	PMID:21888893
Molecular Function	GO:0005515	protein binding	ADNP	IPI	UniProtKB:Q13185	Human	PMID:21888893
Molecular Function	GO:0005515	protein binding	ADNP	IPI	UniProtKB:P83916	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	ADNP	IPI	UniProtKB:Q13185	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	ADNP	IPI	UniProtKB:P45973	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	ADNP	IPI	UniProtKB:P83916	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	ADNP	IPI	UniProtKB:Q13185	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	ADNP	IPI	UniProtKB:Q13185	Human	PMID:29795351
Molecular Function	GO:0005515	protein binding	ADNP	IPI	UniProtKB:Q14839	Human	PMID:29795351
Molecular Function	GO:0005515	protein binding	Adnp	IPI	PR:Q61686	Mouse	PMID:17222401
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Adnp	IDA		Mouse	MGI:MGI:3701370|PMID:17222401
Cellular Component	GO:0030424	axon	Adnp	IDA		Rat	PMID:18072088|RGD:2312789
Cellular Component	GO:0005737	cytoplasm	Adnp	IDA		Rat	PMID:19130308|RGD:2312770
Cellular Component	GO:0005737	cytoplasm	adnpa	IDA		Zfish	PMID:32533114
Cellular Component	GO:0030425	dendrite	Adnp	IDA		Rat	PMID:19130308|RGD:2312770
Cellular Component	GO:0005615	extracellular space	Adnp	IDA		Mouse	PMID:10037502
Cellular Component	GO:0005615	extracellular space	Adnp	IDA		Rat	PMID:16845437|RGD:2312771
Cellular Component	GO:0043025	neuronal cell body	Adnp	IDA		Rat	PMID:19130308|RGD:2312770
Cellular Component	GO:0005634	nucleus	Adnp	IDA		Rat	PMID:16845437|RGD:2312771
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	ADNP	IDA		Human	PMID:29795351
Biological Process	GO:0032147	activation of protein kinase activity	Adnp	IDA		Rat	PMID:19047645|RGD:2312772
Biological Process	GO:0031668	cellular response to extracellular stimulus	Adnp	IEP		Rat	PMID:15518891|RGD:2312774
Biological Process	GO:0019934	cGMP-mediated signaling	Adnp	IDA		Rat	PMID:11438390|RGD:1358228
Biological Process	GO:0009950	dorsal/ventral axis specification	adnpb	IMP	ZFIN:ZDB-GENO-220308-9	Zfish	PMID:32533114
Biological Process	GO:0043249	erythrocyte maturation	adnpb	IMP	ZFIN:ZDB-MRPHLNO-130102-2	Zfish	PMID:23071114
Biological Process	GO:0043249	erythrocyte maturation	adnpa	IMP	ZFIN:ZDB-MRPHLNO-130109-1	Zfish	PMID:23071114
Biological Process	GO:0044849	estrous cycle	Adnp	IEP		Rat	PMID:16023261|RGD:2312777
Biological Process	GO:0033484	intracellular nitric oxide homeostasis	Adnp	IDA		Rat	PMID:16938277|RGD:2312775
Biological Process	GO:0010629	negative regulation of gene expression	Adnp	IDA		Rat	PMID:15314252|RGD:2312780
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Adnp	IDA		Mouse	PMID:10037502
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Adnp	IDA		Rat	PMID:16938277|RGD:2312775
Biological Process	GO:0032091	negative regulation of protein binding	Adnp	IDA		Rat	PMID:14706557|RGD:2312790
Biological Process	GO:0001933	negative regulation of protein phosphorylation	Adnp	IMP		Mouse	MGI:MGI:6447854|PMID:32533114
Biological Process	GO:0050805	negative regulation of synaptic transmission	Adnp	IMP		Rat	PMID:15963648|RGD:2312778
Biological Process	GO:0051402	neuron apoptotic process	Adnp	IDA		Mouse	PMID:10037502
Biological Process	GO:0030182	neuron differentiation	Adnp	IMP		Mouse	MGI:MGI:6447854|PMID:32533114
Biological Process	GO:0045773	positive regulation of axon extension	Adnp	IDA		Rat	PMID:19047645|RGD:2312772
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	Adnp	IMP		Mouse	MGI:MGI:6447854|PMID:32533114
Biological Process	GO:0010976	positive regulation of neuron projection development	Adnp	IDA		Rat	PMID:15800376|RGD:2312779
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	Adnp	IDA		Rat	PMID:19047645|RGD:2312772
Biological Process	GO:0051965	positive regulation of synapse assembly	Adnp	IDA		Rat	PMID:15800376|RGD:2312779
Biological Process	GO:0010468	regulation of gene expression	Adnp	IMP		Mouse	MGI:MGI:6447854|PMID:32533114
Biological Process	GO:0050767	regulation of neurogenesis	adnpb	IMP	ZFIN:ZDB-GENO-220308-9	Zfish	PMID:32533114
Biological Process	GO:0050767	regulation of neurogenesis	adnpa	IMP	ZFIN:ZDB-GENO-220308-9	Zfish	PMID:32533114
Biological Process	GO:0010835	regulation of protein ADP-ribosylation	Adnp	IDA		Rat	PMID:16093393|RGD:1601081
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Adnp	IDA		Mouse	MGI:MGI:3701370|PMID:17222401
Biological Process	GO:0009743	response to carbohydrate	Adnp	IEP		Rat	PMID:19130308|RGD:2312770
Biological Process	GO:0010035	response to inorganic substance	Adnp	IEP		Rat	PMID:18571851|RGD:2312773
Biological Process	GO:0007614	short-term memory	Adnp	IDA		Rat	PMID:12212775|RGD:2312781
Biological Process	GO:0044332	Wnt signaling pathway involved in dorsal/ventral axis specification	adnpa	IMP	ZFIN:ZDB-GENO-220308-9	Zfish	PMID:32533114

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern