Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ADRA1D
  • Mouse genes Adra1d
  • Rat genes Adra1d
  • Zfish genes adra1d
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Adra1d

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004937	alpha1-adrenergic receptor activity	Adra1d	IDA		Mouse	PMID:12595294
Molecular Function	GO:0004937	alpha1-adrenergic receptor activity	Adra1d	IDA		Rat	PMID:11171057|RGD:68202
Molecular Function	GO:0042802	identical protein binding	ADRA1D	IPI	UniProtKB:P25100	Human	PMID:14645668
Molecular Function	GO:0042802	identical protein binding	ADRA1D	IPI	UniProtKB:P25100	Human	PMID:26617989
Molecular Function	GO:0042802	identical protein binding	ADRA1D	IPI	UniProtKB:P25100	Human	PMID:27382054
Molecular Function	GO:0005515	protein binding	ADRA1D	IPI	UniProtKB:Q13424	Human	PMID:16533813
Molecular Function	GO:0005515	protein binding	ADRA1D	IPI	UniProtKB:Q13425	Human	PMID:16533813
Molecular Function	GO:0005515	protein binding	ADRA1D	IPI	UniProtKB:Q61234	Human	PMID:16533813
Molecular Function	GO:0005515	protein binding	ADRA1D	IPI	UniProtKB:Q925E0	Human	PMID:16533813
Molecular Function	GO:0005515	protein binding	ADRA1D	IPI	UniProtKB:Q99L88	Human	PMID:16533813
Molecular Function	GO:0005515	protein binding	ADRA1D	IPI	UniProtKB:Q13424	Human	PMID:18468998
Molecular Function	GO:0005515	protein binding	ADRA1D	IPI	UniProtKB:Q13425	Human	PMID:18468998
Molecular Function	GO:0005515	protein binding	ADRA1D	IPI	UniProtKB:Q13425	Human	PMID:21115837
Molecular Function	GO:0005515	protein binding	ADRA1D	IPI	UniProtKB:Q14160	Human	PMID:24550280
Molecular Function	GO:0005515	protein binding	ADRA1D	IPI	UniProtKB:P21333	Human	PMID:26460884
Molecular Function	GO:0005515	protein binding	ADRA1D	IPI	UniProtKB:Q13424	Human	PMID:26617989
Molecular Function	GO:0005515	protein binding	ADRA1D	IPI	UniProtKB:Q13425	Human	PMID:26617989
Molecular Function	GO:0005515	protein binding	ADRA1D	IPI	UniProtKB:Q14160	Human	PMID:26617989
Molecular Function	GO:0005515	protein binding	ADRA1D	IPI	UniProtKB:Q13424	Human	PMID:27382054
Molecular Function	GO:0005515	protein binding	ADRA1D	IPI	UniProtKB:Q13425	Human	PMID:27382054
Molecular Function	GO:0005515	protein binding	ADRA1D	IPI	UniProtKB:Q14160	Human	PMID:27382054
Cellular Component	GO:0005829	cytosol	Adra1d	IDA		Rat	PMID:20511116|RGD:5688334
Biological Process	GO:0060073	micturition	Adra1d	IMP		Rat	PMID:20668103|RGD:5688347
Biological Process	GO:0001986	negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure	Adra1d	IMP		Mouse	PMID:12595294
Biological Process	GO:0150099	neuron-glial cell signaling	Adra1d	IGI	UniProtKB:P97717,UniProtKB:P97718	Mouse	MGI:MGI:6294365|PMID:10493741
Biological Process	GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure	Adra1d	IMP		Mouse	PMID:12595294
Biological Process	GO:0045907	positive regulation of vasoconstriction	Adra1d	IMP		Rat	PMID:17199872|RGD:5688350
Biological Process	GO:0008217	regulation of blood pressure	Adra1d	IMP		Mouse	PMID:26531127

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern