Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ADSL
  • Mouse genes Adsl
  • Rat genes Adsl
  • Zfish genes adsl
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Adsl

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070626	(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity	ADSL	IDA		Human	PMID:27590927
Molecular Function	GO:0070626	(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity	Adsl	IMP		Mouse	PMID:6480832
Molecular Function	GO:0070626	(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity	Adsl	IDA		Rat	PMID:3759987|RGD:5135303
Molecular Function	GO:0042802	identical protein binding	ADSL	IDA		Human	PMID:16973378
Molecular Function	GO:0042802	identical protein binding	Adsl	IPI	RGD:1307617	Rat	PMID:3689310|RGD:1598764
Molecular Function	GO:0004018	N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity	ADSL	IDA		Human	PMID:16973378
Molecular Function	GO:0004018	N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity	ADSL	IDA		Human	PMID:19405474
Molecular Function	GO:0004018	N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity	Adsl	IDA		Mouse	PMID:5891253
Molecular Function	GO:0004018	N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity	Adsl	IDA		Rat	PMID:3689310|RGD:1598764
Molecular Function	GO:0004018	N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity	Adsl	IDA		Rat	PMID:8887278|RGD:1598763
Cellular Component	GO:0005829	cytosol	ADSL	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Adsl	IDA		Rat	PMID:8887278|RGD:1598763
Cellular Component	GO:0005739	mitochondrion	Adsl	HDA		Mouse	PMID:18614015
Cellular Component	GO:0032991	protein-containing complex	ADSL	IDA		Human	PMID:16973378
Biological Process	GO:0044208	'de novo' AMP biosynthetic process	Adsl	IMP		Mouse	PMID:6480832
Biological Process	GO:0044208	'de novo' AMP biosynthetic process	Adsl	IDA		Mouse	PMID:5891253
Biological Process	GO:0006189	'de novo' IMP biosynthetic process	Adsl	IMP		Mouse	PMID:6480832
Biological Process	GO:0097294	'de novo' XMP biosynthetic process	Adsl	IMP		Mouse	PMID:6480832
Biological Process	GO:0009060	aerobic respiration	Adsl	IMP		Rat	PMID:3777158|RGD:1598765
Biological Process	GO:0006167	AMP biosynthetic process	ADSL	IDA		Human	PMID:11428554
Biological Process	GO:0006167	AMP biosynthetic process	Adsl	IDA		Rat	PMID:3759987|RGD:5135303
Biological Process	GO:0044209	AMP salvage	Adsl	IDA		Mouse	PMID:25681585
Biological Process	GO:0006177	GMP biosynthetic process	Adsl	IMP		Mouse	PMID:6480832
Biological Process	GO:0006163	purine nucleotide metabolic process	Adsl	IDA		Rat	PMID:3689310|RGD:1598764
Biological Process	GO:0006163	purine nucleotide metabolic process	Adsl	IMP		Rat	PMID:3777158|RGD:1598765
Biological Process	GO:0006163	purine nucleotide metabolic process	Adsl	IDA		Rat	PMID:8887278|RGD:1598763
Biological Process	GO:0001666	response to hypoxia	Adsl	IEP		Rat	PMID:8887278|RGD:1598763
Biological Process	GO:0014850	response to muscle activity	Adsl	IEP		Rat	PMID:3777158|RGD:1598765
Biological Process	GO:0007584	response to nutrient	Adsl	IDA		Rat	PMID:7128902|RGD:1598767
Biological Process	GO:0042594	response to starvation	Adsl	IEP		Rat	PMID:690130|RGD:5135454
Biological Process	GO:0009156	ribonucleoside monophosphate biosynthetic process	Adsl	IDA		Rat	PMID:3759987|RGD:5135303

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern