Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AFP
  • Mouse genes Afp
  • Rat genes Afp
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Afp

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	AFP	IPI	UniProtKB:Q99IB8:PRO_0000045596	Human	PMID:26808496
Cellular Component	GO:0005737	cytoplasm	Afp	IDA		Mouse	PMID:8607965
Cellular Component	GO:0005737	cytoplasm	Afp	IDA		Rat	PMID:17880577|RGD:2292043
Cellular Component	GO:0005829	cytosol	Afp	IDA		Rat	PMID:6174948|RGD:126848735
Cellular Component	GO:0005615	extracellular space	Afp	IDA		Mouse	PMID:67170
Cellular Component	GO:0005615	extracellular space	Afp	IDA		Mouse	PMID:2456965
Cellular Component	GO:0005615	extracellular space	Afp	IDA		Mouse	PMID:12297623
Cellular Component	GO:0005615	extracellular space	Afp	IDA		Rat	PMID:1711115|RGD:2292061
Cellular Component	GO:0005615	extracellular space	Afp	IDA		Rat	PMID:6174948|RGD:126848735
Biological Process	GO:0031100	animal organ regeneration	Afp	IEP		Rat	PMID:17828713|RGD:2292044
Biological Process	GO:0071300	cellular response to retinoic acid	Afp	IEP		Rat	PMID:7539613|RGD:126790586
Biological Process	GO:0001889	liver development	Afp	IEP		Rat	PMID:16822301|RGD:2292045
Biological Process	GO:0097421	liver regeneration	Afp	IEP		Rat	PMID:2460696|RGD:126848734
Biological Process	GO:0001542	ovulation from ovarian follicle	Afp	IMP	MGI:MGI:2388722	Mouse	PMID:12297623
Biological Process	GO:0031016	pancreas development	Afp	IEP		Rat	PMID:17880577|RGD:2292043
Biological Process	GO:0042448	progesterone metabolic process	Afp	IMP	MGI:MGI:2388722	Mouse	PMID:12297623
Biological Process	GO:0071548	response to dexamethasone	Afp	IEP		Rat	PMID:2409527|RGD:126790584
Biological Process	GO:0009408	response to heat	Afp	IEP		Rat	PMID:7521703|RGD:126790585
Biological Process	GO:0010033	response to organic substance	Afp	IEP		Rat	PMID:1711115|RGD:2292061
Biological Process	GO:0019953	sexual reproduction	Afp	IMP	MGI:MGI:2388722	Mouse	PMID:12297623
Biological Process	GO:0060395	SMAD protein signal transduction	Afp	IDA		Mouse	PMID:9420335

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern