Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AFTPH
  • Mouse genes Aftph
  • Rat genes Aftph
  • Zfish genes aftpha,aftphb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aftph

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030276	clathrin binding	AFTPH	IDA		Human	PMID:15758025
Molecular Function	GO:0005515	protein binding	AFTPH	IPI	UniProtKB:P63010	Human	PMID:35044719
Cellular Component	GO:0030121	AP-1 adaptor complex	AFTPH	IDA		Human	PMID:15758025
Cellular Component	GO:0005737	cytoplasm	aftphb	IDA		Zfish	PMID:25139857
Cellular Component	GO:0005829	cytosol	AFTPH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	AFTPH	IDA		Human	PMID:15758025
Cellular Component	GO:0005794	Golgi apparatus	AFTPH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	AFTPH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	AFTPH	IDA		Human	GO_REF:0000052
Biological Process	GO:0003341	cilium movement	aftphb	IMP	ZFIN:ZDB-MRPHLNO-141110-1	Zfish	PMID:25139857

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern