Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AGR2
  • Mouse genes Agr2
  • Rat genes Agr2
  • Zfish genes agr2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Agr2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0002162	dystroglycan binding	AGR2	IDA		Human	PMID:12592373
Molecular Function	GO:0005154	epidermal growth factor receptor binding	AGR2	IPI	UniProtKB:P00533	Human	PMID:25666625
Molecular Function	GO:0042802	identical protein binding	AGR2	IPI	UniProtKB:O95994	Human	PMID:23220234
Molecular Function	GO:0042802	identical protein binding	AGR2	IPI	UniProtKB:O95994	Human	PMID:23274113
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q14118	Human	PMID:12592373
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q96HA1	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q02817	Human	PMID:19359471
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:P11021	Human	PMID:23220234
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:P12104	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q15323	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q8NEC5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q96HA1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q9H1M0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q9UMX0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q9UMX0-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:P12104	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:A0A024R4Z4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:A0A024R8A9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:A0A0S2Z4U3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:O00303	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:O14796	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:O15116	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:O15182	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:O15197-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:O43681	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:O43765	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:O75575-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:O75716	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:O95741-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:O95833	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:O95954	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:O95983-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:P01024	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:P08631-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:P12268	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:P16220	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:P20618	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:P25786	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:P28906	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:P29597	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:P34810	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:P43080	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:P49069	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:P60660	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:P62875	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:P62993	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:P78424	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:P82980	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q06547	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q08117-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q12797-6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q12933	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q14119	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q15323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q15560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q16656-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q24JT5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q2WGJ6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q5T7W7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q6BCY4-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q6P1L5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q6UX98	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q6ZR62	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q6ZYL4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q7KZS0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q7Z3B4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q7Z3K3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q7Z6R9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q86VK4-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q8NDX5-7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q8NE01	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q8NEC5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q8TCE9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q8TEB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q969Y2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q96EQ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q96FH0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q96FV9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q96HA1-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q96HA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q96HQ2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q96L73-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q99633	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q9BQ89	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q9BVL2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q9H1M0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q9H2F3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q9NP66	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q9NWB1-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q9NZH5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q9UBH0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q9UH17-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q9UIG4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q9UMX0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q9Y6T4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:X5D778	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGR2	IPI	UniProtKB:Q9Y371	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Agr2	IPI	PR:Q9R0Q3	Mouse	PMID:31040128
Cellular Component	GO:0005783	endoplasmic reticulum	AGR2	IMP		Human	PMID:22184114
Cellular Component	GO:0005783	endoplasmic reticulum	Agr2	IDA		Mouse	PMID:19359471
Cellular Component	GO:0005576	extracellular region	AGR2	IDA		Human	PMID:15834940
Cellular Component	GO:0005615	extracellular space	AGR2	IDA		Human	PMID:22184114
Cellular Component	GO:0005615	extracellular space	AGR2	IDA		Human	PMID:24251762
Cellular Component	GO:0005739	mitochondrion	Agr2	HDA		Mouse	PMID:18614015
Biological Process	GO:0048546	digestive tract morphogenesis	Agr2	IMP		Mouse	MGI:MGI:5634869|PMID:25666625
Biological Process	GO:0006954	inflammatory response	Agr2	IMP		Mouse	PMID:31040128
Biological Process	GO:0060575	intestinal epithelial cell differentiation	agr2	IMP	ZFIN:ZDB-MRPHLNO-120430-1,ZFIN:ZDB-MRPHLNO-120503-1	Zfish	PMID:22514630
Biological Process	GO:0060480	lung goblet cell differentiation	Agr2	IDA		Mouse	PMID:22675208
Biological Process	GO:0070254	mucus secretion	Agr2	IMP	MGI:MGI:3844570	Mouse	PMID:19359471
Biological Process	GO:0060548	negative regulation of cell death	AGR2	IMP		Human	PMID:23220234
Biological Process	GO:0010811	positive regulation of cell-substrate adhesion	AGR2	IMP		Human	PMID:23274113
Biological Process	GO:0048639	positive regulation of developmental growth	Agr2	IMP		Mouse	MGI:MGI:5634869|PMID:25666625
Biological Process	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	AGR2	IMP		Human	PMID:25666625
Biological Process	GO:0010628	positive regulation of gene expression	AGR2	IMP		Human	PMID:22184114
Biological Process	GO:1903896	positive regulation of IRE1-mediated unfolded protein response	AGR2	IDA		Human	PMID:23220234
Biological Process	GO:1903899	positive regulation of PERK-mediated unfolded protein response	AGR2	IDA		Human	PMID:23220234
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	AGR2	IMP		Human	PMID:25666625

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern