Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AGRP
  • Mouse genes Agrp
  • Rat genes Agrp
  • Zfish genes agrp
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Agrp

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005184	neuropeptide hormone activity	AGRP	IDA		Human	PMID:15927146
Molecular Function	GO:0005184	neuropeptide hormone activity	Agrp	IDA		Mouse	PMID:9311920
Molecular Function	GO:0005184	neuropeptide hormone activity	agrp	IDA		Zfish	PMID:14709799
Molecular Function	GO:0070996	type 1 melanocortin receptor binding	agrp	IDA		Zfish	PMID:20980662
Molecular Function	GO:0031781	type 3 melanocortin receptor binding	agrp	IDA		Zfish	PMID:20980662
Molecular Function	GO:0031782	type 4 melanocortin receptor binding	agrp	IDA		Zfish	PMID:20980662
Cellular Component	GO:0005615	extracellular space	AGRP	IDA		Human	PMID:15927146
Cellular Component	GO:0005615	extracellular space	Agrp	IDA		Rat	PMID:19632697|RGD:6480232
Cellular Component	GO:0005796	Golgi lumen	AGRP	IDA		Human	PMID:15927146
Cellular Component	GO:0043025	neuronal cell body	Agrp	IDA		Rat	PMID:20736052|RGD:6480212
Biological Process	GO:0008343	adult feeding behavior	Agrp	IDA		Mouse	PMID:17873059
Biological Process	GO:0008343	adult feeding behavior	Agrp	IEP		Rat	PMID:22425130|RGD:6480661
Biological Process	GO:0007623	circadian rhythm	Agrp	IEP		Rat	PMID:21060311|RGD:8693680
Biological Process	GO:0048589	developmental growth	agrp	IMP	ZFIN:ZDB-MRPHLNO-130226-1	Zfish	PMID:22245570
Biological Process	GO:0048589	developmental growth	agrp	IGI	ZFIN:ZDB-MRPHLNO-130226-1,ZFIN:ZDB-MRPHLNO-130913-2	Zfish	PMID:23869017
Biological Process	GO:0048589	developmental growth	agrp	IGI	ZFIN:ZDB-MRPHLNO-130226-1	Zfish	PMID:23869017
Biological Process	GO:0042755	eating behavior	Agrp	IMP		Rat	PMID:16604086|RGD:1625227
Biological Process	GO:0007631	feeding behavior	agrp	IMP	ZFIN:ZDB-GENO-200602-1	Zfish	PMID:31178320
Biological Process	GO:0048571	long-day photoperiodism	Agrp	IEP		Rat	PMID:19490367|RGD:6480663
Biological Process	GO:0060135	maternal process involved in female pregnancy	Agrp	IEP		Rat	PMID:21303957|RGD:6480202
Biological Process	GO:0007218	neuropeptide signaling pathway	AGRP	IDA		Human	PMID:15927146
Biological Process	GO:0007218	neuropeptide signaling pathway	Agrp	IDA		Mouse	PMID:9311920
Biological Process	GO:0007218	neuropeptide signaling pathway	Agrp	IEP		Rat	PMID:10875247|RGD:632165
Biological Process	GO:0007218	neuropeptide signaling pathway	agrp	IDA		Zfish	PMID:14709799
Biological Process	GO:2000253	positive regulation of feeding behavior	Agrp	IMP		Rat	PMID:20551287|RGD:6480222
Biological Process	GO:2000253	positive regulation of feeding behavior	Agrp	IDA		Rat	PMID:21527895|RGD:6478803
Biological Process	GO:2000253	positive regulation of feeding behavior	agrp	IMP	ZFIN:ZDB-MRPHLNO-130312-9	Zfish	PMID:23300705
Biological Process	GO:2000253	positive regulation of feeding behavior	agrp	IMP	ZFIN:ZDB-MRPHLNO-130312-10	Zfish	PMID:23300705
Biological Process	GO:0060259	regulation of feeding behavior	AGRP	IDA		Human	PMID:15927146
Biological Process	GO:0060259	regulation of feeding behavior	AGRP	IMP		Human	PMID:9311920
Biological Process	GO:0040008	regulation of growth	agrp	IGI	ZFIN:ZDB-GENO-130226-3,ZFIN:ZDB-MRPHLNO-130226-1	Zfish	PMID:22245570
Biological Process	GO:0032868	response to insulin	Agrp	IEP		Rat	PMID:11179781|RGD:2314004
Biological Process	GO:0007165	signal transduction	Agrp	IDA		Mouse	MGI:MGI:1097480|PMID:9311920

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern