Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Agtr1b

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes AGTR1
- Mouse genes Agtr1b
- Rat genes Agtr1b
- Zfish genes agtr1a,agtr1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Agtr1b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001596	angiotensin type I receptor activity	AGTR1	IDA		Human	PMID:10993080
Molecular Function	GO:0001596	angiotensin type I receptor activity	AGTR1	IPI	UniProtKB:P01019	Human	PMID:1378723
Molecular Function	GO:0001596	angiotensin type I receptor activity	AGTR1	IDA		Human	PMID:15611106
Molecular Function	GO:0001596	angiotensin type I receptor activity	AGTR1	IDA		Human	PMID:25913193
Molecular Function	GO:0001596	angiotensin type I receptor activity	AGTR1	IDA		Human	PMID:26420482
Molecular Function	GO:0001596	angiotensin type I receptor activity	AGTR1	IDA		Human	PMID:30639100
Molecular Function	GO:0001596	angiotensin type I receptor activity	AGTR1	IDA		Human	PMID:32079768
Molecular Function	GO:0001596	angiotensin type I receptor activity	AGTR1	IDA		Human	PMID:8987975
Molecular Function	GO:0004945	angiotensin type II receptor activity	AGTR1	IDA		Human	PMID:1567413
Molecular Function	GO:0031711	bradykinin receptor binding	AGTR1	IPI	UniProtKB:P30411	Human	PMID:10993080
Molecular Function	GO:0005515	protein binding	AGTR1	IPI	UniProtKB:P01019	Human	PMID:1378723
Molecular Function	GO:0005515	protein binding	AGTR1	IPI	UniProtKB:P32121	Human	PMID:15611106
Molecular Function	GO:0005515	protein binding	AGTR1	IPI	UniProtKB:P49407	Human	PMID:15611106
Molecular Function	GO:0005515	protein binding	AGTR1	IPI	UniProtKB:P41495	Human	PMID:19023134
Molecular Function	GO:0005515	protein binding	AGTR1	IPI	UniProtKB:P35414	Human	PMID:21412239
Molecular Function	GO:0005515	protein binding	AGTR1	IPI	UniProtKB:P35414	Human	PMID:22935142
Molecular Function	GO:0005515	protein binding	AGTR1	IPI	UniProtKB:P01019:PRO_0000032458	Human	PMID:23597562
Molecular Function	GO:0005515	protein binding	AGTR1	IPI	UniProtKB:P21333	Human	PMID:26460884
Molecular Function	GO:0005515	protein binding	AGTR1	IPI	UniProtKB:O75937	Human	PMID:28298427
Molecular Function	GO:0005515	protein binding	AGTR1	IPI	UniProtKB:P05026	Human	PMID:28298427
Molecular Function	GO:0005515	protein binding	AGTR1	IPI	UniProtKB:P54368	Human	PMID:28298427
Molecular Function	GO:0005515	protein binding	AGTR1	IPI	UniProtKB:Q6ZMG9	Human	PMID:28298427
Molecular Function	GO:0046982	protein heterodimerization activity	AGTR1	IPI	UniProtKB:P30411	Human	PMID:10993080
Cellular Component	GO:0005886	plasma membrane	AGTR1	IDA		Human	PMID:19023134
Cellular Component	GO:0005886	plasma membrane	AGTR1	IDA		Human	PMID:33713620
Biological Process	GO:0038166	angiotensin-activated signaling pathway	AGTR1	IDA		Human	PMID:1567413
Biological Process	GO:0038166	angiotensin-activated signaling pathway	Agtr1b	IMP		Rat	PMID:21769867\|RGD:5688337
Biological Process	GO:0038166	angiotensin-activated signaling pathway	Agtr1b	IMP		Rat	PMID:7862653\|RGD:10047113
Biological Process	GO:0001568	blood vessel development	Agtr1b	IGI	MGI:MGI:87964	Mouse	PMID:9466969
Biological Process	GO:0019722	calcium-mediated signaling	AGTR1	IDA		Human	PMID:1567413
Biological Process	GO:0060326	cell chemotaxis	AGTR1	IDA		Human	PMID:15635042
Biological Process	GO:0071549	cellular response to dexamethasone stimulus	Agtr1b	IDA		Rat	PMID:17537984\|RGD:1643596
Biological Process	GO:0042756	drinking behavior	Agtr1b	IGI	MGI:MGI:87964	Mouse	PMID:10880053
Biological Process	GO:0042756	drinking behavior	Agtr1b	IMP	MGI:MGI:2157020	Mouse	PMID:10880053
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	AGTR1	IDA		Human	PMID:1378723
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Agtr1b	IMP		Rat	PMID:12446719\|RGD:629553
Biological Process	GO:0006954	inflammatory response	Agtr1b	IGI	MGI:MGI:87966	Mouse	PMID:19404405
Biological Process	GO:0006954	inflammatory response	Agtr1b	IGI	MGI:MGI:87964	Mouse	PMID:19404405
Biological Process	GO:0001822	kidney development	AGTR1	IMP		Human	PMID:16116425
Biological Process	GO:0001822	kidney development	Agtr1b	IGI	MGI:MGI:87965	Mouse	PMID:9466969
Biological Process	GO:0002034	maintenance of blood vessel diameter homeostasis by renin-angiotensin	AGTR1	IDA		Human	PMID:25913193
Biological Process	GO:0002034	maintenance of blood vessel diameter homeostasis by renin-angiotensin	AGTR1	IDA		Human	PMID:26420482
Biological Process	GO:0051402	neuron apoptotic process	Agtr1b	IMP		Mouse	PMID:9310306
Biological Process	GO:0086097	phospholipase C-activating angiotensin-activated signaling pathway	AGTR1	IDA		Human	PMID:1378723
Biological Process	GO:0045777	positive regulation of blood pressure	Agtr1b	IMP		Rat	PMID:21769867\|RGD:5688337
Biological Process	GO:1903589	positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	AGTR1	IGI	RNAcentral:URS0000338542_9606	Human	PMID:25850724
Biological Process	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	Agtr1b	IMP		Rat	PMID:17537984\|RGD:1643596
Biological Process	GO:1905920	positive regulation of CoA-transferase activity	AGTR1	IMP		Human	PMID:18971559
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	AGTR1	IDA		Human	PMID:1567413
Biological Process	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	AGTR1	IDA		Human	PMID:1567413
Biological Process	GO:0010744	positive regulation of macrophage derived foam cell differentiation	AGTR1	IMP		Human	PMID:18971559
Biological Process	GO:0032430	positive regulation of phospholipase A2 activity	AGTR1	IMP		Human	PMID:17069818
Biological Process	GO:0051247	positive regulation of protein metabolic process	AGTR1	IMP		Human	PMID:18971559
Biological Process	GO:0008217	regulation of blood pressure	Agtr1b	IMP		Mouse	PMID:26531127
Biological Process	GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	Agtr1b	IGI	MGI:MGI:87964	Mouse	PMID:9466969
Biological Process	GO:0019229	regulation of vasoconstriction	AGTR1	IDA		Human	PMID:15117835
Biological Process	GO:1990776	response to angiotensin	Agtr1b	IEP		Rat	PMID:8986922\|RGD:10047122
Biological Process	GO:0043627	response to estrogen	Agtr1b	IDA		Rat	PMID:12810582\|RGD:1598880
Biological Process	GO:0001666	response to hypoxia	Agtr1b	IEP		Rat	PMID:11115779\|RGD:1598884
Biological Process	GO:0035902	response to immobilization stress	Agtr1b	IEP		Rat	PMID:11979053\|RGD:1598882
Biological Process	GO:0035094	response to nicotine	Agtr1b	IEP		Rat	PMID:22728133\|RGD:10047110
Biological Process	GO:0007584	response to nutrient	Agtr1b	IEP		Rat	PMID:9062366\|RGD:1598887
Biological Process	GO:0009651	response to salt stress	Agtr1b	IEP		Rat	PMID:12023680\|RGD:10047098
Biological Process	GO:0009410	response to xenobiotic stimulus	Agtr1b	IEP		Rat	PMID:15998842\|RGD:1598879
Biological Process	GO:0007266	Rho protein signal transduction	AGTR1	IDA		Human	PMID:15611106
Biological Process	GO:0046718	viral entry into host cell	AGTR1	IDA		Human	PMID:33713620

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.