Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AGXT
  • Mouse genes Agxt
  • Rat genes Agxt
  • Zfish genes agxta,agxtb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Agxt

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008453	alanine-glyoxylate transaminase activity	AGXT	IDA		Human	PMID:10960483
Molecular Function	GO:0008453	alanine-glyoxylate transaminase activity	AGXT	IMP		Human	PMID:12777626
Molecular Function	GO:0008453	alanine-glyoxylate transaminase activity	AGXT	IDA		Human	PMID:16971151
Molecular Function	GO:0008453	alanine-glyoxylate transaminase activity	AGXT	IDA		Human	PMID:17696873
Molecular Function	GO:0008453	alanine-glyoxylate transaminase activity	AGXT	IDA		Human	PMID:18492492
Molecular Function	GO:0008453	alanine-glyoxylate transaminase activity	AGXT	IDA		Human	PMID:22198249
Molecular Function	GO:0008453	alanine-glyoxylate transaminase activity	Agxt	IMP		Mouse	PMID:17110443
Molecular Function	GO:0008453	alanine-glyoxylate transaminase activity	Agxt	IDA		Rat	PMID:12383475|RGD:1599457
Molecular Function	GO:0016597	amino acid binding	AGXT	IDA		Human	PMID:18492492
Molecular Function	GO:0016597	amino acid binding	Agxt	IDA		Rat	PMID:12383475|RGD:1599457
Molecular Function	GO:0042802	identical protein binding	AGXT	IPI	UniProtKB:P21549	Human	PMID:12899834
Molecular Function	GO:0042802	identical protein binding	AGXT	IPI	UniProtKB:P21549	Human	PMID:22529745
Molecular Function	GO:0042802	identical protein binding	AGXT	IPI	UniProtKB:P21549	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:P50542	Human	PMID:15911627
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:P50542-1	Human	PMID:22529745
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:A1KXE4-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:O15496	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:O43281-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:O43482	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:O60711	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:O76011	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:O76014	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:P0C7T5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:P0DPK4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:P49356	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:P49639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:P53539	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:P60328	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:Q07627	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:Q15323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:Q5BKX5-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:Q5TD97	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:Q5VZ52	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:Q5W111-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:Q6A162	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:Q6DKK2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:Q6ZR37	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:Q8HWS3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:Q8IUC2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:Q8WVR3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:Q99750	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:Q9BYQ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:Q9BYR8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:Q9H5F2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:Q9NQX0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:Q9NR55	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AGXT	IPI	UniProtKB:Q9UKJ5	Human	PMID:32296183
Molecular Function	GO:0042803	protein homodimerization activity	AGXT	IDA		Human	PMID:10960483
Molecular Function	GO:0042803	protein homodimerization activity	AGXT	IDA		Human	PMID:12777626
Molecular Function	GO:0042803	protein homodimerization activity	AGXT	IDA		Human	PMID:12899834
Molecular Function	GO:0042803	protein homodimerization activity	AGXT	IDA		Human	PMID:16971151
Molecular Function	GO:0042803	protein homodimerization activity	AGXT	IDA		Human	PMID:20133649
Molecular Function	GO:0043621	protein self-association	AGXT	IDA		Human	PMID:16971151
Molecular Function	GO:0030170	pyridoxal phosphate binding	AGXT	IMP		Human	PMID:15802217
Molecular Function	GO:0030170	pyridoxal phosphate binding	AGXT	IDA		Human	PMID:17696873
Molecular Function	GO:0030170	pyridoxal phosphate binding	AGXT	IDA		Human	PMID:20133649
Molecular Function	GO:0004760	serine-pyruvate transaminase activity	AGXT	IDA		Human	PMID:10347152
Molecular Function	GO:0004760	serine-pyruvate transaminase activity	Agxt	IDA		Rat	PMID:3894025|RGD:1598894
Molecular Function	GO:0008483	transaminase activity	AGXT	IDA		Human	PMID:18492492
Molecular Function	GO:0008483	transaminase activity	AGXT	IDA		Human	PMID:20133649
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	AGXT	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005759	mitochondrial matrix	Agxt	IDA		Rat	PMID:14561759|RGD:1580664
Cellular Component	GO:0005739	mitochondrion	Agxt	IDA		Rat	PMID:10739960|RGD:1599461
Cellular Component	GO:0005739	mitochondrion	Agxt	IDA		Rat	PMID:3900009|RGD:1598890
Cellular Component	GO:0005782	peroxisomal matrix	AGXT	IDA		Human	PMID:22198249
Cellular Component	GO:0005782	peroxisomal matrix	AGXT	IDA		Human	PMID:3418107
Cellular Component	GO:0005777	peroxisome	AGXT	IDA		Human	PMID:10960483
Cellular Component	GO:0005777	peroxisome	AGXT	IDA		Human	PMID:12777626
Cellular Component	GO:0005777	peroxisome	AGXT	IDA		Human	PMID:1703535
Cellular Component	GO:0005777	peroxisome	AGXT	IDA		Human	PMID:3709805
Cellular Component	GO:0005777	peroxisome	AGXT	IDA		Human	PMID:7813517
Cellular Component	GO:0005777	peroxisome	AGXT	IDA		Human	PMID:9053548
Cellular Component	GO:0005777	peroxisome	Agxt	IDA		Rat	PMID:10739960|RGD:1599461
Cellular Component	GO:0005777	peroxisome	Agxt	IDA		Rat	PMID:14561759|RGD:1580664
Cellular Component	GO:0005777	peroxisome	Agxt	IDA		Rat	PMID:3900009|RGD:1598890
Biological Process	GO:0071391	cellular response to estrogen stimulus	agxtb	IDA		Zfish	PMID:18618001
Biological Process	GO:0019265	glycine biosynthetic process, by transamination of glyoxylate	AGXT	IDA		Human	PMID:22198249
Biological Process	GO:0019265	glycine biosynthetic process, by transamination of glyoxylate	Agxt	IDA		Rat	PMID:12383475|RGD:1599457
Biological Process	GO:0009436	glyoxylate catabolic process	AGXT	IDA		Human	PMID:22198249
Biological Process	GO:0046487	glyoxylate metabolic process	AGXT	IDA		Human	PMID:12777626
Biological Process	GO:0046487	glyoxylate metabolic process	AGXT	IMP		Human	PMID:3709805
Biological Process	GO:0046487	glyoxylate metabolic process	Agxt	IMP	MGI:MGI:3526219	Mouse	PMID:17110443
Biological Process	GO:0042853	L-alanine catabolic process	AGXT	IDA		Human	PMID:17696873
Biological Process	GO:0042853	L-alanine catabolic process	AGXT	IDA		Human	PMID:18492492
Biological Process	GO:0042853	L-alanine catabolic process	AGXT	IDA		Human	PMID:22198249
Biological Process	GO:0019448	L-cysteine catabolic process	AGXT	IDA		Human	PMID:18492492
Biological Process	GO:0006563	L-serine metabolic process	AGXT	IDA		Human	PMID:10347152
Biological Process	GO:0007219	Notch signaling pathway	Agxt	IDA		Mouse	PMID:25446530
Biological Process	GO:0046724	oxalic acid secretion	Agxt	IMP	MGI:MGI:3526219	Mouse	PMID:17110443
Biological Process	GO:0042866	pyruvate biosynthetic process	Agxt	IDA		Rat	PMID:12383475|RGD:1599457
Biological Process	GO:0051591	response to cAMP	Agxt	IDA		Rat	PMID:17958|RGD:1598892
Biological Process	GO:0051384	response to glucocorticoid	Agxt	IDA		Rat	PMID:167860|RGD:1598893

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern