Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AHSG
  • Mouse genes Ahsg
  • Rat genes Ahsg
  • Zfish genes ahsg1,ahsg2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ahsg

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030294	receptor signaling protein tyrosine kinase inhibitor activity	Ahsg	IDA		Rat	PMID:2766355|RGD:632173
Cellular Component	GO:0072562	blood microparticle	AHSG	HDA		Human	PMID:22516433
Cellular Component	GO:0062023	collagen-containing extracellular matrix	AHSG	HDA		Human	PMID:27559042
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Ahsg	IDA		Rat	PMID:7794128|RGD:1626075
Cellular Component	GO:0070062	extracellular exosome	AHSG	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	AHSG	HDA		Human	PMID:23533145
Cellular Component	GO:0005576	extracellular region	AHSG	HDA		Human	PMID:27068509
Cellular Component	GO:0005615	extracellular space	AHSG	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	Ahsg	IDA		Rat	PMID:11239198|RGD:1625796
Cellular Component	GO:0005794	Golgi apparatus	AHSG	IDA		Human	GO_REF:0000052
Cellular Component	GO:0032991	protein-containing complex	Ahsg	IDA		Rat	PMID:12676928|RGD:1582508
Biological Process	GO:0006953	acute-phase response	AHSG	IDA		Human	PMID:12153747
Biological Process	GO:0031100	animal organ regeneration	Ahsg	IEP		Rat	PMID:1659407|RGD:1625795
Biological Process	GO:0032869	cellular response to insulin stimulus	Ahsg	IEP		Rat	PMID:7513166|RGD:1626076
Biological Process	GO:0021987	cerebral cortex development	Ahsg	IEP		Rat	PMID:2423927|RGD:1626077
Biological Process	GO:0008584	male gonad development	Ahsg	IMP		Rat	PMID:6530227|RGD:1626078
Biological Process	GO:0030502	negative regulation of bone mineralization	Ahsg	IDA		Mouse	MGI:MGI:3687916|PMID:12556469
Biological Process	GO:0030502	negative regulation of bone mineralization	Ahsg	IMP		Rat	PMID:8702833|RGD:1626074
Biological Process	GO:0030308	negative regulation of cell growth	Ahsg	IDA		Rat	PMID:2766355|RGD:632173
Biological Process	GO:0046627	negative regulation of insulin receptor signaling pathway	Ahsg	IDA		Rat	PMID:2766355|RGD:632173
Biological Process	GO:0001503	ossification	Ahsg	IDA		Mouse	PMID:8695840
Biological Process	GO:0045780	positive regulation of bone resorption	Ahsg	IMP		Rat	PMID:10500999|RGD:1625797
Biological Process	GO:0050766	positive regulation of phagocytosis	AHSG	IDA		Human	PMID:12725640
Biological Process	GO:0065003	protein-containing complex assembly	Ahsg	IPI	RGD:3088|RGD:3305|RGD:708488|RGD:68322|ChEBI:35156|ChEBI:26020	Rat	PMID:12676928|RGD:1582508
Biological Process	GO:0050727	regulation of inflammatory response	AHSG	IMP		Human	PMID:12642050

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern