Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AICDA
  • Mouse genes Aicda
  • Rat genes Aicda
  • Zfish genes aicda
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aicda

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004126	cytidine deaminase activity	AICDA	IDA		Human	PMID:18722174
Molecular Function	GO:0004126	cytidine deaminase activity	Aicda	IMP		Mouse	MGI:MGI:2656023|PMID:12692563
Molecular Function	GO:0004126	cytidine deaminase activity	Aicda	IDA		Mouse	PMID:10373455
Molecular Function	GO:0004126	cytidine deaminase activity	aicda	IDA		Zfish	PMID:23585279
Molecular Function	GO:0004126	cytidine deaminase activity	aicda	IDA		Zfish	PMID:22198384
Molecular Function	GO:0042802	identical protein binding	AICDA	IPI	UniProtKB:Q9GZX7	Human	PMID:19412186
Molecular Function	GO:0005515	protein binding	AICDA	IPI	UniProtKB:P10644	Human	PMID:16387847
Molecular Function	GO:0005515	protein binding	AICDA	IPI	UniProtKB:P17612	Human	PMID:16387847
Molecular Function	GO:0005515	protein binding	AICDA	IPI	UniProtKB:Q8WYA6	Human	PMID:18722174
Molecular Function	GO:0005515	protein binding	AICDA	IPI	UniProtKB:O00505	Human	PMID:19412186
Molecular Function	GO:0005515	protein binding	AICDA	IPI	UniProtKB:O15131	Human	PMID:19412186
Molecular Function	GO:0005515	protein binding	AICDA	IPI	UniProtKB:P52294	Human	PMID:19412186
Molecular Function	GO:0005515	protein binding	AICDA	IPI	UniProtKB:P52294	Human	PMID:21385873
Molecular Function	GO:0005515	protein binding	AICDA	IPI	UniProtKB:Q7KZ85	Human	PMID:21518874
Molecular Function	GO:0005515	protein binding	AICDA	IPI	UniProtKB:P24522	Human	PMID:21722948
Molecular Function	GO:0005515	protein binding	AICDA	IPI	UniProtKB:Q13569	Human	PMID:21722948
Molecular Function	GO:0005515	protein binding	AICDA	IPI	UniProtKB:O60884	Human	PMID:22085931
Molecular Function	GO:0005515	protein binding	AICDA	IPI	UniProtKB:P11142	Human	PMID:22085931
Molecular Function	GO:0005515	protein binding	AICDA	IPI	UniProtKB:P31689	Human	PMID:22085931
Molecular Function	GO:0005515	protein binding	AICDA	IPI	UniProtKB:Q784Z8	Human	PMID:26867650
Molecular Function	GO:0005515	protein binding	Aicda	IPI	UniProtKB:Q64511|UniProtKB:Q91Z31	Mouse	MGI:MGI:4946885|PMID:21186367
Molecular Function	GO:0005515	protein binding	Aicda	IPI	UniProtKB:P24522	Mouse	MGI:MGI:5506812|PMID:23820005
Molecular Function	GO:0005515	protein binding	Aicda	IPI	UniProtKB:P09405|UniProtKB:Q62318|UniProtKB:Q62383	Mouse	MGI:MGI:5004983|PMID:21518874
Molecular Function	GO:0031625	ubiquitin protein ligase binding	AICDA	IPI	UniProtKB:Q9BV68	Human	PMID:23277564
Cellular Component	GO:0005737	cytoplasm	AICDA	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005737	cytoplasm	AICDA	IDA		Human	PMID:14769937
Cellular Component	GO:0005737	cytoplasm	AICDA	IDA		Human	PMID:18722174
Cellular Component	GO:0005634	nucleus	AICDA	IDA		Human	PMID:14769937
Cellular Component	GO:0032991	protein-containing complex	AICDA	IPI	GO:0000178	Human	PMID:21255825
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Aicda	IMP		Mouse	PMID:18762567
Biological Process	GO:0009972	cytidine deamination	Aicda	IMP		Mouse	MGI:MGI:2656023|PMID:12692563
Biological Process	GO:0042742	defense response to bacterium	Aicda	IMP	MGI:MGI:2156156	Mouse	PMID:14766966
Biological Process	GO:0042742	defense response to bacterium	Aicda	IGI	MGI:MGI:97849	Mouse	PMID:14766966
Biological Process	GO:0080111	DNA demethylation	AICDA	IDA		Human	PMID:21496894
Biological Process	GO:0045190	isotype switching	Aicda	IMP		Mouse	MGI:MGI:5004983|PMID:21518874
Biological Process	GO:0045190	isotype switching	Aicda	IMP		Mouse	PMID:17713479
Biological Process	GO:0090310	negative regulation of DNA methylation-dependent heterochromatin formation	AICDA	IDA		Human	PMID:21496894
Biological Process	GO:0033262	regulation of nuclear cell cycle DNA replication	AICDA	IMP		Human	PMID:19734146
Biological Process	GO:0016444	somatic cell DNA recombination	aicda	IDA		Zfish	PMID:16291656
Biological Process	GO:0016444	somatic cell DNA recombination	aicda	IDA		Zfish	PMID:16157688
Biological Process	GO:0016445	somatic diversification of immunoglobulins	AICDA	IDA		Human	PMID:18722174
Biological Process	GO:0016446	somatic hypermutation of immunoglobulin genes	AICDA	IMP		Human	PMID:21518874

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern