Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AK3
  • Mouse genes Ak3
  • Rat genes Ak3
  • Zfish genes ak3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ak3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004017	adenylate kinase activity	Ak3	IDA		Rat	PMID:5484813|RGD:2301093
Molecular Function	GO:0042802	identical protein binding	Ak3	IPI	RGD:619885	Rat	PMID:5010295|RGD:5490216
Molecular Function	GO:0042802	identical protein binding	Ak3	IDA		Rat	PMID:5484813|RGD:2301093
Molecular Function	GO:0046899	nucleoside triphosphate adenylate kinase activity	AK3	IDA		Human	PMID:11485571
Molecular Function	GO:0046899	nucleoside triphosphate adenylate kinase activity	AK3	EXP		Human	PMID:218813
Molecular Function	GO:0005515	protein binding	AK3	IPI	UniProtKB:Q92624	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	AK3	IPI	UniProtKB:P23142-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AK3	IPI	UniProtKB:P60410	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AK3	IPI	UniProtKB:Q92624	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AK3	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	AK3	IPI	UniProtKB:P02649	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	AK3	IPI	UniProtKB:P04406	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	AK3	IPI	UniProtKB:P23560-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	AK3	IPI	UniProtKB:P28799	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	AK3	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	AK3	IPI	UniProtKB:Q8WXH2	Human	PMID:32814053
Cellular Component	GO:0005758	mitochondrial intermembrane space	Ak3	IDA		Rat	PMID:5010295|RGD:5490216
Cellular Component	GO:0005759	mitochondrial matrix	Ak3	IDA		Mouse	MGI:MGI:2149139|PMID:11485571
Cellular Component	GO:0005759	mitochondrial matrix	Ak3	IDA		Rat	PMID:9504419|RGD:2301092
Cellular Component	GO:0005739	mitochondrion	AK3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Ak3	IDA		Mouse	MGI:MGI:2682130|PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Ak3	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Ak3	HDA		Mouse	PMID:14651853
Biological Process	GO:0006172	ADP biosynthetic process	Ak3	IDA		Rat	PMID:5010295|RGD:5490216
Biological Process	GO:0006172	ADP biosynthetic process	Ak3	IDA		Rat	PMID:5123889|RGD:5490208
Biological Process	GO:0046033	AMP metabolic process	AK3	IDA		Human	PMID:11485571
Biological Process	GO:0006756	AMP phosphorylation	Ak3	IDA		Rat	PMID:5484813|RGD:2301093
Biological Process	GO:0046034	ATP metabolic process	Ak3	IDA		Rat	PMID:5010295|RGD:5490216
Biological Process	GO:0021549	cerebellum development	Ak3	IEP		Rat	PMID:9920788|RGD:632499
Biological Process	GO:0046060	dATP metabolic process	Ak3	IDA		Rat	PMID:5010295|RGD:5490216
Biological Process	GO:0046039	GTP metabolic process	AK3	IDA		Human	PMID:11485571
Biological Process	GO:0030097	hemopoiesis	ak3	IMP	ZFIN:ZDB-MRPHLNO-160526-11	Zfish	PMID:22139419
Biological Process	GO:0046041	ITP metabolic process	AK3	IDA		Human	PMID:11485571
Biological Process	GO:0001889	liver development	Ak3	IEP		Rat	PMID:5123889|RGD:5490208
Biological Process	GO:0007517	muscle organ development	Ak3	IEP		Rat	PMID:8468325|RGD:5490217
Biological Process	GO:0061515	myeloid cell development	ak3	IMP	ZFIN:ZDB-MRPHLNO-160526-11	Zfish	PMID:22139419
Biological Process	GO:0021772	olfactory bulb development	Ak3	IEP		Rat	PMID:9920788|RGD:632499
Biological Process	GO:0042594	response to starvation	Ak3	IEP		Rat	PMID:14656997|RGD:5490290
Biological Process	GO:0046051	UTP metabolic process	AK3	IDA		Human	PMID:11485571

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern