Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AKAP1
  • Mouse genes Akap1
  • Rat genes Akap1
  • Zfish genes akap1a,akap1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Akap1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0048487	beta-tubulin binding	Akap1	IDA		Rat	PMID:12096916|RGD:2313124
Molecular Function	GO:0008017	microtubule binding	Akap1	IDA		Rat	PMID:12096916|RGD:2313124
Molecular Function	GO:0060090	molecular adaptor activity	Akap1	IDA		Rat	PMID:16756943|RGD:2312597
Molecular Function	GO:0005515	protein binding	AKAP1	IPI	UniProtKB:P13861	Human	PMID:16642035
Molecular Function	GO:0005515	protein binding	AKAP1	IPI	UniProtKB:P13861	Human	PMID:24083380
Molecular Function	GO:0005515	protein binding	AKAP1	IPI	UniProtKB:P13861	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	AKAP1	IPI	UniProtKB:P13861	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	AKAP1	IPI	UniProtKB:Q9H078	Human	PMID:31522117
Molecular Function	GO:0005515	protein binding	Akap1	IPI	UniProtKB:Q06986	Mouse	MGI:MGI:5508596|PMID:18323779
Molecular Function	GO:0005515	protein binding	Akap1	IPI	UniProtKB:Q16825	Mouse	MGI:MGI:3045645|PMID:15143158
Molecular Function	GO:0005515	protein binding	Akap1	IPI	UniProtKB:Q91VD9	Mouse	MGI:MGI:6432573|PMID:32072193
Molecular Function	GO:0034237	protein kinase A regulatory subunit binding	AKAP1	IPI	UniProtKB:P13861	Human	PMID:17911601
Molecular Function	GO:0034237	protein kinase A regulatory subunit binding	Akap1	IDA		Rat	PMID:16756943|RGD:2312597
Molecular Function	GO:0019901	protein kinase binding	Akap1	IPI	RGD:3394	Rat	PMID:16996504|RGD:2312601
Molecular Function	GO:0019901	protein kinase binding	Akap1	IDA		Rat	PMID:9182549|RGD:724797
Molecular Function	GO:0030346	protein phosphatase 2B binding	Akap1	IDA		Rat	PMID:19358331|RGD:2312604
Molecular Function	GO:0019903	protein phosphatase binding	Akap1	IDA		Rat	PMID:16756943|RGD:2312597
Molecular Function	GO:0003723	RNA binding	AKAP1	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	AKAP1	HDA		Human	PMID:22681889
Cellular Component	GO:0005811	lipid droplet	Akap1	IDA		Rat	PMID:16756943|RGD:2312597
Cellular Component	GO:0016020	membrane	AKAP1	HDA		Human	PMID:19946888
Cellular Component	GO:0030061	mitochondrial crista	Akap1	IDA		Rat	PMID:16996504|RGD:2312601
Cellular Component	GO:0005739	mitochondrion	AKAP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Akap1	IDA		Mouse	MGI:MGI:6432573|PMID:32072193
Cellular Component	GO:0005739	mitochondrion	Akap1	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Akap1	HDA		Mouse	PMID:14651853
Cellular Component	GO:0031594	neuromuscular junction	Akap1	IDA		Rat	PMID:11716788|RGD:2313126
Cellular Component	GO:0045211	postsynaptic membrane	Akap1	IDA		Rat	PMID:11716788|RGD:2313126
Cellular Component	GO:0099091	postsynaptic specialization, intracellular component	Akap1	IDA		Rat	PMID:11716788|RGD:2313126
Biological Process	GO:0140374	antiviral innate immune response	AKAP1	IMP		Human	PMID:31522117
Biological Process	GO:0006915	apoptotic process	Akap1	IMP		Mouse	MGI:MGI:6432573|PMID:32072193
Biological Process	GO:0071320	cellular response to cAMP	Akap1	IEP		Rat	PMID:9722570|RGD:2313127
Biological Process	GO:0071375	cellular response to peptide hormone stimulus	Akap1	IEP		Rat	PMID:9722570|RGD:2313127
Biological Process	GO:0010614	negative regulation of cardiac muscle hypertrophy	Akap1	IMP		Rat	PMID:19358331|RGD:2312604
Biological Process	GO:0035308	negative regulation of protein dephosphorylation	Akap1	IMP		Rat	PMID:19358331|RGD:2312604
Biological Process	GO:0042308	negative regulation of protein import into nucleus	Akap1	IMP		Rat	PMID:19358331|RGD:2312604

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern