Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AKAP11
  • Mouse genes Akap11
  • Rat genes Akap11
  • Zfish genes akap11
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Akap11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019207	kinase regulator activity	Akap11	IDA		Rat	PMID:12147701|RGD:8554429
Molecular Function	GO:0005515	protein binding	AKAP11	IPI	UniProtKB:P49841	Human	PMID:27484798
Molecular Function	GO:0005515	protein binding	AKAP11	IPI	UniProtKB:Q99732	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Akap11	IPI	PR:Q9D9W0	Mouse	PMID:30026308
Molecular Function	GO:0034236	protein kinase A catalytic subunit binding	Akap11	IDA		Rat	PMID:8621616|RGD:632175
Molecular Function	GO:0034237	protein kinase A regulatory subunit binding	Akap11	IPI	UniProtKB:Q9DBC7	Mouse	PMID:21502359
Molecular Function	GO:0034237	protein kinase A regulatory subunit binding	Akap11	IDA		Rat	PMID:8621616|RGD:632175
Molecular Function	GO:0008157	protein phosphatase 1 binding	Akap11	IDA		Rat	PMID:10209101|RGD:14349025
Cellular Component	GO:0005737	cytoplasm	Akap11	IDA		Rat	PMID:19008911|RGD:2312636
Cellular Component	GO:0005737	cytoplasm	Akap11	IDA		Rat	PMID:8621616|RGD:632175
Cellular Component	GO:0005829	cytosol	AKAP11	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	AKAP11	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005777	peroxisome	Akap11	IDA		Rat	PMID:8621616|RGD:632175
Cellular Component	GO:0005886	plasma membrane	AKAP11	IDA		Human	GO_REF:0000052
Cellular Component	GO:0032991	protein-containing complex	Akap11	IDA		Rat	PMID:18385542|RGD:2312637
Cellular Component	GO:0032991	protein-containing complex	Akap11	IDA		Rat	PMID:8621616|RGD:632175
Biological Process	GO:0030866	cortical actin cytoskeleton organization	Akap11	IMP	MGI:5751858	Mouse	PMID:27402760
Biological Process	GO:1903142	positive regulation of establishment of endothelial barrier	Akap11	IMP		Rat	PMID:25188285|RGD:14348953
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Akap11	IMP		Rat	PMID:18385542|RGD:2312637
Biological Process	GO:0008104	protein localization	Akap11	IMP	MGI:5751858	Mouse	PMID:27402760
Biological Process	GO:0036010	protein localization to endosome	Akap11	IDA		Mouse	PMID:21502359
Biological Process	GO:0036010	protein localization to endosome	Akap11	IMP		Mouse	PMID:21502359
Biological Process	GO:0003091	renal water homeostasis	Akap11	IMP	MGI:5751858	Mouse	PMID:27402760

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern