Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AKAP4
  • Mouse genes Akap4
  • Rat genes Akap4
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Akap4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	AKAP4	IPI	UniProtKB:P36873-2	Human	PMID:27913189
Molecular Function	GO:0005515	protein binding	Akap4	IPI	UniProtKB:P12367|UniProtKB:Q9DBC7	Mouse	MGI:MGI:1328474|PMID:9852104
Molecular Function	GO:0005515	protein binding	Akap4	IPI	UniProtKB:Q91YE8	Mouse	MGI:MGI:3768463|PMID:17923693
Molecular Function	GO:0005515	protein binding	Akap4	IPI	UniProtKB:Q9D424	Mouse	MGI:MGI:4944160|PMID:20731842
Molecular Function	GO:0005515	protein binding	Akap4	IPI	PR:Q8C042	Mouse	PMID:23675479
Molecular Function	GO:0005515	protein binding	Akap4	IPI	PR:A2ARZ3	Mouse	PMID:12606363
Molecular Function	GO:0005515	protein binding	Akap4	IPI	PR:Q9D3V5	Mouse	PMID:12606363
Molecular Function	GO:0005515	protein binding	Akap4	IPI	PR:O88987	Mouse	PMID:12606363
Molecular Function	GO:0051018	protein kinase A binding	Akap4	IPI	UniProtKB:Q9DBC7	Mouse	MGI:MGI:1328474|PMID:9852104
Cellular Component	GO:0005929	cilium	Akap4	IDA		Mouse	PMID:21715716
Cellular Component	GO:0031514	motile cilium	AKAP4	IDA		Human	PMID:9822690
Cellular Component	GO:0031514	motile cilium	Akap4	IDA		Mouse	MGI:MGI:1328474|PMID:9852104
Cellular Component	GO:0005634	nucleus	AKAP4	HDA		Human	PMID:21630459
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Akap4	IDA		Mouse	MGI:MGI:3768463|PMID:17923693
Cellular Component	GO:0097224	sperm connecting piece	AKAP4	IDA		Human	PMID:30745215
Cellular Component	GO:0097229	sperm end piece	AKAP4	IDA		Human	PMID:30745215
Cellular Component	GO:0035686	sperm fibrous sheath	Akap4	IDA		Mouse	PMID:16687649
Cellular Component	GO:0097225	sperm midpiece	AKAP4	IDA		Human	PMID:30745215
Cellular Component	GO:0097228	sperm principal piece	AKAP4	IDA		Human	PMID:30137358
Cellular Component	GO:0097228	sperm principal piece	AKAP4	IDA		Human	PMID:30745215
Cellular Component	GO:0097228	sperm principal piece	Akap4	IDA		Mouse	PMID:12606363
Cellular Component	GO:0030018	Z disc	Akap4	IDA		Mouse	MGI:MGI:3768463|PMID:17923693
Biological Process	GO:0051649	establishment of localization in cell	Akap4	IMP	MGI:MGI:2684287	Mouse	PMID:15385410
Biological Process	GO:0045184	establishment of protein localization	Akap4	IMP	MGI:MGI:2684287	Mouse	PMID:15385410
Biological Process	GO:0030317	flagellated sperm motility	AKAP4	IMP		Human	PMID:9822690
Biological Process	GO:0030317	flagellated sperm motility	Akap4	IMP		Mouse	MGI:MGI:1328474|PMID:9852104
Biological Process	GO:0008104	protein localization	Akap4	IMP	UniProtKB:P31324	Mouse	PMID:8088444
Biological Process	GO:0120316	sperm flagellum assembly	Akap4	IMP	MGI:MGI:2684287	Mouse	PMID:15385410
Biological Process	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	Akap4	IPI	UniProtKB:P31324	Mouse	PMID:9852104

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern