Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ALPG,ALPI
  • Mouse genes Akp3
  • Rat genes Akp3
  • Zfish genes alpi.1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Akp3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004035	alkaline phosphatase activity	ALPG	IDA		Human	PMID:1939159
Molecular Function	GO:0004035	alkaline phosphatase activity	Akp3	IDA		Rat	PMID:15885097|RGD:2300084
Molecular Function	GO:0000287	magnesium ion binding	Akp3	IDA		Rat	PMID:15885097|RGD:2300084
Molecular Function	GO:0002020	protease binding	ALPI	IPI	UniProtKB:P80067	Human	PMID:18307834
Molecular Function	GO:0005515	protein binding	ALPI	IPI	UniProtKB:P60410	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ALPI	IPI	UniProtKB:P60411	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ALPI	IPI	UniProtKB:Q7Z3S9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ALPI	IPI	UniProtKB:Q7Z3S9	Human	PMID:31515488
Molecular Function	GO:0008270	zinc ion binding	Akp3	IDA		Rat	PMID:15885097|RGD:2300084
Cellular Component	GO:0005903	brush border	Akp3	IDA		Mouse	MGI:MGI:5621262|PMID:22114352
Cellular Component	GO:0009897	external side of plasma membrane	Akp3	IDA		Rat	PMID:7744844|RGD:2300082
Cellular Component	GO:0005886	plasma membrane	ALPI	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ALPG	IDA		Human	GO_REF:0000052
Biological Process	GO:0035264	multicellular organism growth	Akp3	IMP	MGI:MGI:1856293	Mouse	PMID:1682057
Biological Process	GO:0021915	neural tube development	Akp3	IMP	MGI:MGI:1856293	Mouse	PMID:1682057
Biological Process	GO:0022008	neurogenesis	Akp3	IMP	MGI:MGI:1856293	Mouse	PMID:1682057
Biological Process	GO:0006793	phosphorus metabolic process	Akp3	IDA		Rat	PMID:15885097|RGD:2300084
Biological Process	GO:0036342	post-anal tail morphogenesis	Akp3	IMP	MGI:MGI:1856293	Mouse	PMID:1682057
Biological Process	GO:0031667	response to nutrient levels	Akp3	IEP		Rat	PMID:9021713|RGD:14349031

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern