Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AKR1C4
  • Mouse genes Akr1c12
  • Rat genes Akr1c12,Akr1c12l1,Akr1c13
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Akr1c12

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047023	androsterone dehydrogenase activity	AKR1C4	IDA		Human	PMID:21851338
Molecular Function	GO:0047743	chlordecone reductase activity	AKR1C4	IDA		Human	PMID:2427522
Molecular Function	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	AKR1C4	IDA		Human	PMID:20837989
Molecular Function	GO:0001758	retinal dehydrogenase activity	AKR1C4	IDA		Human	PMID:21851338
Cellular Component	GO:0070062	extracellular exosome	AKR1C4	HDA		Human	PMID:23533145
Biological Process	GO:0071395	cellular response to jasmonic acid stimulus	AKR1C4	IDA		Human	PMID:19487289
Biological Process	GO:0044597	daunorubicin metabolic process	AKR1C4	IMP		Human	PMID:20837989
Biological Process	GO:0044598	doxorubicin metabolic process	AKR1C4	IMP		Human	PMID:20837989

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern