Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Alad

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ALAD
- Mouse genes Alad
- Rat genes Alad
- Zfish genes alad
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Alad

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	ALAD	IPI	UniProtKB:P13716	Human	PMID:11032836
Molecular Function	GO:0004655	porphobilinogen synthase activity	ALAD	IDA		Human	PMID:11032836
Molecular Function	GO:0004655	porphobilinogen synthase activity	ALAD	IDA		Human	PMID:8175643
Molecular Function	GO:0004655	porphobilinogen synthase activity	Alad	IDA		Mouse	PMID:4959158
Molecular Function	GO:0004655	porphobilinogen synthase activity	Alad	IDA		Mouse	PMID:14050799
Molecular Function	GO:0004655	porphobilinogen synthase activity	Alad	IDA		Mouse	PMID:4981581
Molecular Function	GO:0004655	porphobilinogen synthase activity	Alad	IDA		Rat	PMID:19095280\|RGD:4144201
Molecular Function	GO:1904854	proteasome core complex binding	Alad	IDA		Rat	PMID:21640720\|RGD:12904696
Molecular Function	GO:0008270	zinc ion binding	ALAD	IDA		Human	PMID:11032836
Cellular Component	GO:0005829	cytosol	Alad	IDA		Rat	PMID:2394940\|RGD:1599023
Cellular Component	GO:0070062	extracellular exosome	ALAD	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	Alad	IDA		Rat	PMID:19111884\|RGD:2306421
Cellular Component	GO:0005634	nucleus	ALAD	HDA		Human	PMID:21630459
Biological Process	GO:0071353	cellular response to interleukin-4	Alad	IDA		Mouse	PMID:9798653
Biological Process	GO:0071284	cellular response to lead ion	Alad	IEP		Rat	PMID:16566714\|RGD:4144781
Biological Process	GO:0006783	heme biosynthetic process	ALAD	IDA		Human	PMID:11032836
Biological Process	GO:0006783	heme biosynthetic process	Alad	IDA		Mouse	PMID:14050799
Biological Process	GO:0006783	heme biosynthetic process	Alad	IDA		Mouse	PMID:4959158
Biological Process	GO:0006783	heme biosynthetic process	Alad	IDA		Mouse	PMID:4981581
Biological Process	GO:0006783	heme biosynthetic process	Alad	IDA		Rat	PMID:1764448\|RGD:1599020
Biological Process	GO:1901799	negative regulation of proteasomal protein catabolic process	ALAD	IDA		Human	PMID:8175643
Biological Process	GO:0051260	protein homooligomerization	ALAD	IPI	UniProtKB:P13716	Human	PMID:11032836
Biological Process	GO:0014823	response to activity	Alad	IEP		Rat	PMID:12171438\|RGD:4144186
Biological Process	GO:0010044	response to aluminum ion	Alad	IEP		Rat	PMID:518129\|RGD:4144207
Biological Process	GO:0043200	response to amino acid	Alad	IEP		Rat	PMID:8295845\|RGD:4144812
Biological Process	GO:0046685	response to arsenic-containing substance	Alad	IDA		Rat	PMID:17086449\|RGD:1599015
Biological Process	GO:0046685	response to arsenic-containing substance	Alad	IEP		Rat	PMID:19966145\|RGD:4144139
Biological Process	GO:0046686	response to cadmium ion	Alad	IEP		Rat	PMID:20019094\|RGD:4144138
Biological Process	GO:0046686	response to cadmium ion	Alad	IDA		Rat	PMID:7896311\|RGD:1599018
Biological Process	GO:0032025	response to cobalt ion	Alad	IEP		Rat	PMID:826600\|RGD:1599026
Biological Process	GO:0045471	response to ethanol	Alad	IDA		Rat	PMID:2394940\|RGD:1599023
Biological Process	GO:0070542	response to fatty acid	Alad	IEP		Rat	PMID:20026167\|RGD:4144137
Biological Process	GO:0051384	response to glucocorticoid	Alad	IEP		Rat	PMID:12596873\|RGD:4144180
Biological Process	GO:0009635	response to herbicide	Alad	IEP		Rat	PMID:12180188\|RGD:4144184
Biological Process	GO:0009725	response to hormone	Alad	IEP		Rat	PMID:17720948\|RGD:4144163
Biological Process	GO:0009725	response to hormone	Alad	IEP		Rat	PMID:9468112\|RGD:4144792
Biological Process	GO:0001666	response to hypoxia	Alad	IEP		Rat	PMID:3697363\|RGD:4144802
Biological Process	GO:0010035	response to inorganic substance	Alad	IEP		Rat	PMID:19743388\|RGD:4144200
Biological Process	GO:0010212	response to ionizing radiation	Alad	IEP		Rat	PMID:17916974\|RGD:4144160
Biological Process	GO:0010039	response to iron ion	Alad	IEP		Rat	PMID:14598909\|RGD:4144204
Biological Process	GO:0010288	response to lead ion	Alad	IEP		Rat	PMID:16597373\|RGD:1599014
Biological Process	GO:0032496	response to lipopolysaccharide	Alad	IEP		Rat	PMID:19344711\|RGD:4144148
Biological Process	GO:0046689	response to mercury ion	Alad	IEP		Rat	PMID:17881112\|RGD:4144162
Biological Process	GO:0010038	response to metal ion	Alad	IDA		Rat	PMID:15302091\|RGD:1599017
Biological Process	GO:0010038	response to metal ion	Alad	IEP		Rat	PMID:3629603\|RGD:4144818
Biological Process	GO:0051597	response to methylmercury	Alad	IEP		Rat	PMID:19874286\|RGD:4144140
Biological Process	GO:0007584	response to nutrient	Alad	IDA		Rat	PMID:2394940\|RGD:1599023
Biological Process	GO:0031667	response to nutrient levels	Alad	IEP		Rat	PMID:8000239\|RGD:4144797
Biological Process	GO:0014070	response to organic cyclic compound	Alad	IEP		Rat	PMID:19647414\|RGD:4144142
Biological Process	GO:0010033	response to organic substance	Alad	IDA		Rat	PMID:12853123\|RGD:1299047
Biological Process	GO:0010033	response to organic substance	Alad	IDA		Rat	PMID:826600\|RGD:1599026
Biological Process	GO:0006979	response to oxidative stress	Alad	IEP		Rat	PMID:17916976\|RGD:4144203
Biological Process	GO:0070541	response to platinum ion	Alad	IEP		Rat	PMID:925603\|RGD:4144822
Biological Process	GO:0010269	response to selenium ion	Alad	IEP		Rat	PMID:15721883\|RGD:4144175
Biological Process	GO:0009636	response to toxic substance	Alad	IEP		Rat	PMID:20517888\|RGD:4144135
Biological Process	GO:0033273	response to vitamin	Alad	IEP		Rat	PMID:9559098\|RGD:4144791
Biological Process	GO:0010266	response to vitamin B1	Alad	IEP		Rat	PMID:20088549\|RGD:4144199
Biological Process	GO:0033197	response to vitamin E	Alad	IEP		Rat	PMID:17572058\|RGD:4144165
Biological Process	GO:0009410	response to xenobiotic stimulus	Alad	IEP		Rat	PMID:19486337\|RGD:4144144
Biological Process	GO:0009410	response to xenobiotic stimulus	Alad	IDA		Rat	PMID:8070841\|RGD:1599019
Biological Process	GO:0010043	response to zinc ion	Alad	IDA		Rat	PMID:3987589\|RGD:1599024

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.