Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ALDH18A1
  • Mouse genes Aldh18a1
  • Rat genes Aldh18a1
  • Zfish genes aldh18a1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aldh18a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004349	glutamate 5-kinase activity	ALDH18A1	IDA		Human	PMID:11092761
Molecular Function	GO:0004349	glutamate 5-kinase activity	ALDH18A1	IMP		Human	PMID:26297558
Molecular Function	GO:0004349	glutamate 5-kinase activity	Aldh18a1	IDA		Mouse	PMID:10037775
Molecular Function	GO:0004350	glutamate-5-semialdehyde dehydrogenase activity	ALDH18A1	IDA		Human	PMID:11092761
Molecular Function	GO:0004350	glutamate-5-semialdehyde dehydrogenase activity	ALDH18A1	IMP		Human	PMID:26297558
Molecular Function	GO:0042802	identical protein binding	ALDH18A1	IDA		Human	PMID:26297558
Molecular Function	GO:0005515	protein binding	ALDH18A1	IPI	UniProtKB:Q6RW13	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ALDH18A1	IPI	UniProtKB:Q96DZ9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ALDH18A1	IPI	UniProtKB:O75208	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALDH18A1	IPI	UniProtKB:Q6PI48	Human	PMID:32296183
Molecular Function	GO:0003723	RNA binding	ALDH18A1	HDA		Human	PMID:22658674
Cellular Component	GO:0031966	mitochondrial membrane	Aldh18a1	IDA		Rat	PMID:6131890|RGD:13439717
Cellular Component	GO:0005739	mitochondrion	ALDH18A1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	ALDH18A1	IDA		Human	PMID:26297558
Cellular Component	GO:0005739	mitochondrion	ALDH18A1	IDA		Human	PMID:26320891
Cellular Component	GO:0005739	mitochondrion	Aldh18a1	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Aldh18a1	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Aldh18a1	IDA		Rat	PMID:6139090|RGD:13439716
Biological Process	GO:0019240	citrulline biosynthetic process	ALDH18A1	IMP		Human	PMID:11092761
Biological Process	GO:0019240	citrulline biosynthetic process	ALDH18A1	IMP		Human	PMID:26297558
Biological Process	GO:0006536	glutamate metabolic process	ALDH18A1	IMP		Human	PMID:11092761
Biological Process	GO:0006592	ornithine biosynthetic process	ALDH18A1	IMP		Human	PMID:11092761
Biological Process	GO:0006592	ornithine biosynthetic process	ALDH18A1	IMP		Human	PMID:26297558
Biological Process	GO:0006561	proline biosynthetic process	ALDH18A1	IMP		Human	PMID:11092761
Biological Process	GO:0006561	proline biosynthetic process	ALDH18A1	IMP		Human	PMID:26297558
Biological Process	GO:0009266	response to temperature stimulus	Aldh18a1	IDA		Rat	PMID:6131890|RGD:13439717

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern