Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ALDH1A2
  • Mouse genes Aldh1a2
  • Rat genes Aldh1a2
  • Zfish genes aldh1a2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aldh1a2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity	Aldh1a2	IDA		Mouse	PMID:12610736
Molecular Function	GO:0016918	retinal binding	Aldh1a2	IDA		Rat	PMID:8663198|RGD:724800
Molecular Function	GO:0001758	retinal dehydrogenase activity	ALDH1A2	IDA		Human	PMID:29240402
Molecular Function	GO:0001758	retinal dehydrogenase activity	Aldh1a2	IDA		Mouse	PMID:8797830
Molecular Function	GO:0001758	retinal dehydrogenase activity	Aldh1a2	IDA		Rat	PMID:12547725|RGD:1576367
Cellular Component	GO:0005737	cytoplasm	ALDH1A2	IDA		Human	PMID:18495959
Cellular Component	GO:0005829	cytosol	Aldh1a2	IDA		Rat	PMID:12547725|RGD:1576367
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Aldh1a2	IDA		Rat	PMID:21138835|RGD:6771354
Biological Process	GO:0042904	9-cis-retinoic acid biosynthetic process	Aldh1a2	IDA		Mouse	PMID:11876656
Biological Process	GO:0009952	anterior/posterior pattern specification	Aldh1a2	IMP	MGI:MGI:1857891	Mouse	PMID:16368932
Biological Process	GO:0009952	anterior/posterior pattern specification	Aldh1a2	IMP	MGI:MGI:2180721	Mouse	PMID:15872003
Biological Process	GO:0009952	anterior/posterior pattern specification	Aldh1a2	IGI	MGI:MGI:1096359	Mouse	PMID:17067568
Biological Process	GO:0009952	anterior/posterior pattern specification	Aldh1a2	IGI	MGI:MGI:2679699	Mouse	PMID:17067568
Biological Process	GO:0009952	anterior/posterior pattern specification	Aldh1a2	IMP	MGI:MGI:2180721	Mouse	PMID:15652703
Biological Process	GO:0009952	anterior/posterior pattern specification	aldh1a2	IMP	ZFIN:ZDB-GENO-000412-4	Zfish	PMID:15342476
Biological Process	GO:0009952	anterior/posterior pattern specification	aldh1a2	IMP	ZFIN:ZDB-GENO-000412-4	Zfish	PMID:15196955
Biological Process	GO:0048318	axial mesoderm development	aldh1a2	IMP	ZFIN:ZDB-GENO-000412-4	Zfish	PMID:11688558
Biological Process	GO:0001568	blood vessel development	Aldh1a2	IMP	MGI:MGI:1857891	Mouse	PMID:14627725
Biological Process	GO:0043010	camera-type eye development	Aldh1a2	IMP	MGI:MGI:2180721	Mouse	PMID:15366004
Biological Process	GO:0043010	camera-type eye development	Aldh1a2	IMP	MGI:MGI:1857891	Mouse	PMID:16368932
Biological Process	GO:0048593	camera-type eye morphogenesis	aldh1a2	IMP	ZFIN:ZDB-MRPHLNO-050316-2	Zfish	PMID:22125274
Biological Process	GO:0048738	cardiac muscle tissue development	Aldh1a2	IMP		Mouse	PMID:9892670
Biological Process	GO:0008283	cell population proliferation	Aldh1a2	IMP	MGI:MGI:1857891	Mouse	PMID:16368932
Biological Process	GO:0071300	cellular response to retinoic acid	Aldh1a2	IEP		Mouse	MGI:MGI:3809313|PMID:18816858
Biological Process	GO:0022010	central nervous system myelination	aldh1a2	IMP	ZFIN:ZDB-GENO-100823-2	Zfish	PMID:16839543
Biological Process	GO:0009855	determination of bilateral symmetry	Aldh1a2	IMP	MGI:MGI:1857891	Mouse	PMID:15731404
Biological Process	GO:0007368	determination of left/right symmetry	aldh1a2	IMP	ZFIN:ZDB-GENO-000412-4	Zfish	PMID:15889082
Biological Process	GO:0007368	determination of left/right symmetry	aldh1a2	IMP	ZFIN:ZDB-MRPHLNO-050316-2	Zfish	PMID:15889082
Biological Process	GO:0048546	digestive tract morphogenesis	aldh1a2	IMP	ZFIN:ZDB-GENO-070802-3	Zfish	PMID:15967793
Biological Process	GO:0031076	embryonic camera-type eye development	Aldh1a2	IGI	MGI:MGI:1861722	Mouse	PMID:17184764
Biological Process	GO:0048566	embryonic digestive tract development	Aldh1a2	IMP	MGI:MGI:1857891	Mouse	PMID:16806149
Biological Process	GO:0035115	embryonic forelimb morphogenesis	Aldh1a2	IMP	MGI:MGI:2180721	Mouse	PMID:15069081
Biological Process	GO:0035115	embryonic forelimb morphogenesis	Aldh1a2	IMP	MGI:MGI:2180721	Mouse	PMID:20034106
Biological Process	GO:0030326	embryonic limb morphogenesis	Aldh1a2	IMP	MGI:MGI:2180721	Mouse	PMID:14623241
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	aldh1a2	IMP	ZFIN:ZDB-MRPHLNO-050316-2	Zfish	PMID:22125274
Biological Process	GO:0060324	face development	Aldh1a2	IGI	MGI:MGI:1861722	Mouse	PMID:17184764
Biological Process	GO:0060324	face development	Aldh1a2	IMP	MGI:MGI:1857891	Mouse	PMID:17184764
Biological Process	GO:0060325	face morphogenesis	aldh1a2	IMP	ZFIN:ZDB-MRPHLNO-050316-2	Zfish	PMID:22125274
Biological Process	GO:0031101	fin regeneration	aldh1a2	IMP	ZFIN:ZDB-MRPHLNO-100517-4	Zfish	PMID:19801676
Biological Process	GO:0030900	forebrain development	Aldh1a2	IMP	MGI:MGI:1857891	Mouse	PMID:16368932
Biological Process	GO:0003007	heart morphogenesis	Aldh1a2	IMP	MGI:MGI:1857891	Mouse	PMID:11245568
Biological Process	GO:0030902	hindbrain development	Aldh1a2	IMP	MGI:MGI:2180721	Mouse	PMID:15872003
Biological Process	GO:0021575	hindbrain morphogenesis	aldh1a2	IMP	ZFIN:ZDB-GENO-070802-3	Zfish	PMID:11688558
Biological Process	GO:0001822	kidney development	Aldh1a2	IEP		Rat	PMID:15567713|RGD:2306322
Biological Process	GO:0001889	liver development	Aldh1a2	IEP		Rat	PMID:14729401|RGD:1643117
Biological Process	GO:0001889	liver development	aldh1a2	IMP	ZFIN:ZDB-GENO-070802-3	Zfish	PMID:12176331
Biological Process	GO:0001889	liver development	aldh1a2	IMP	ZFIN:ZDB-MRPHLNO-080215-1	Zfish	PMID:22982668
Biological Process	GO:0030324	lung development	Aldh1a2	IMP	MGI:MGI:1857891	Mouse	PMID:16806149
Biological Process	GO:0030324	lung development	Aldh1a2	IMP	MGI:MGI:1857891	Mouse	PMID:16427040
Biological Process	GO:0007494	midgut development	Aldh1a2	IEP		Rat	PMID:15964596|RGD:1643113
Biological Process	GO:0016331	morphogenesis of embryonic epithelium	Aldh1a2	IMP	MGI:MGI:2180721	Mouse	PMID:15739227
Biological Process	GO:0022011	myelination in peripheral nervous system	aldh1a2	IMP	ZFIN:ZDB-GENO-100823-2	Zfish	PMID:16839543
Biological Process	GO:0008285	negative regulation of cell population proliferation	ALDH1A2	IDA		Human	PMID:16166285
Biological Process	GO:0014032	neural crest cell development	Aldh1a2	IGI	MGI:MGI:1096359	Mouse	PMID:17067568
Biological Process	GO:0014032	neural crest cell development	Aldh1a2	IGI	MGI:MGI:2679699	Mouse	PMID:17067568
Biological Process	GO:0014032	neural crest cell development	Aldh1a2	IMP	MGI:MGI:1857891	Mouse	PMID:16368932
Biological Process	GO:0021915	neural tube development	ALDH1A2	IMP		Human	PMID:16237707
Biological Process	GO:0030182	neuron differentiation	Aldh1a2	IMP	MGI:MGI:2451316	Mouse	PMID:15753214
Biological Process	GO:0030182	neuron differentiation	Aldh1a2	IMP	MGI:MGI:2180721	Mouse	PMID:15652703
Biological Process	GO:0031016	pancreas development	Aldh1a2	IMP	MGI:MGI:1857891	Mouse	PMID:16026781
Biological Process	GO:0031016	pancreas development	Aldh1a2	IMP	MGI:MGI:2180721	Mouse	PMID:15739227
Biological Process	GO:0031016	pancreas development	aldh1a2	IMP	ZFIN:ZDB-GENO-070802-3	Zfish	PMID:20011517
Biological Process	GO:0031016	pancreas development	aldh1a2	IMP	ZFIN:ZDB-GENO-100106-1	Zfish	PMID:20011517
Biological Process	GO:0031016	pancreas development	aldh1a2	IMP	ZFIN:ZDB-MRPHLNO-050316-3	Zfish	PMID:20011517
Biological Process	GO:0031016	pancreas development	aldh1a2	IMP	ZFIN:ZDB-MRPHLNO-050316-3	Zfish	PMID:16452093
Biological Process	GO:0061131	pancreas field specification	aldh1a2	IMP	ZFIN:ZDB-GENO-070802-3	Zfish	PMID:12176331
Biological Process	GO:0048339	paraxial mesoderm development	aldh1a2	IMP	ZFIN:ZDB-GENO-000412-4	Zfish	PMID:11688558
Biological Process	GO:0033339	pectoral fin development	aldh1a2	IMP	ZFIN:ZDB-GENO-070802-3	Zfish	PMID:23623500
Biological Process	GO:0033339	pectoral fin development	aldh1a2	IMP	ZFIN:ZDB-MRPHLNO-100517-4	Zfish	PMID:20927131
Biological Process	GO:0033339	pectoral fin development	aldh1a2	IMP	ZFIN:ZDB-GENO-000412-4	Zfish	PMID:11688558
Biological Process	GO:0021983	pituitary gland development	Aldh1a2	IEP		Rat	PMID:17180597|RGD:2306413
Biological Process	GO:0072015	podocyte development	aldh1a2	IMP	ZFIN:ZDB-GENO-070802-3	Zfish	PMID:25078510
Biological Process	GO:0072015	podocyte development	aldh1a2	IMP	ZFIN:ZDB-GENO-141029-2	Zfish	PMID:25078510
Biological Process	GO:0043065	positive regulation of apoptotic process	Aldh1a2	IMP	MGI:MGI:2180721	Mouse	PMID:20034106
Biological Process	GO:0008284	positive regulation of cell population proliferation	Aldh1a2	IMP	MGI:MGI:1857891	Mouse	PMID:16368932
Biological Process	GO:0010628	positive regulation of gene expression	Aldh1a2	IMP	MGI:MGI:2180721	Mouse	PMID:20034106
Biological Process	GO:0039023	pronephric duct morphogenesis	aldh1a2	IMP	ZFIN:ZDB-GENO-110914-3	Zfish	PMID:21761484
Biological Process	GO:0039023	pronephric duct morphogenesis	aldh1a2	IMP	ZFIN:ZDB-GENO-110914-4	Zfish	PMID:21761484
Biological Process	GO:0039023	pronephric duct morphogenesis	aldh1a2	IGI	ZFIN:ZDB-GENO-070802-3,ZFIN:ZDB-MRPHLNO-110815-1,ZFIN:ZDB-MRPHLNO-110815-2	Zfish	PMID:21761484
Biological Process	GO:0039023	pronephric duct morphogenesis	aldh1a2	IMP	ZFIN:ZDB-GENO-070802-3	Zfish	PMID:21761484
Biological Process	GO:0048793	pronephros development	aldh1a2	IMP	ZFIN:ZDB-MRPHLNO-080215-1	Zfish	PMID:17953490
Biological Process	GO:0051289	protein homotetramerization	ALDH1A2	IDA		Human	PMID:29240402
Biological Process	GO:0009954	proximal/distal pattern formation	Aldh1a2	IMP	MGI:MGI:2180721	Mouse	PMID:15069081
Biological Process	GO:0009954	proximal/distal pattern formation	Aldh1a2	IMP	MGI:MGI:2180721	Mouse	PMID:14623241
Biological Process	GO:0048385	regulation of retinoic acid receptor signaling pathway	aldh1a2	IMP	ZFIN:ZDB-MRPHLNO-050316-3	Zfish	PMID:23937294
Biological Process	GO:1905562	regulation of vascular endothelial cell proliferation	Aldh1a2	IMP	MGI:MGI:1857891	Mouse	PMID:14627725
Biological Process	GO:0034097	response to cytokine	ALDH1A2	IDA		Human	PMID:18495959
Biological Process	GO:0032355	response to estradiol	Aldh1a2	IEP		Rat	PMID:15205379|RGD:1576366
Biological Process	GO:0032526	response to retinoic acid	ALDH1A2	IMP		Human	PMID:33565183
Biological Process	GO:0033189	response to vitamin A	Aldh1a2	IEP		Rat	PMID:11169459|RGD:2306337
Biological Process	GO:0042574	retinal metabolic process	Aldh1a2	IDA		Mouse	PMID:12610736
Biological Process	GO:0002138	retinoic acid biosynthetic process	ALDH1A2	IDA		Human	PMID:29240402
Biological Process	GO:0002138	retinoic acid biosynthetic process	ALDH1A2	IMP		Human	PMID:33565183
Biological Process	GO:0002138	retinoic acid biosynthetic process	Aldh1a2	IEP		Rat	PMID:15950969|RGD:6771322
Biological Process	GO:0002138	retinoic acid biosynthetic process	Aldh1a2	IMP		Rat	PMID:21138835|RGD:6771354
Biological Process	GO:0042573	retinoic acid metabolic process	ALDH1A2	IMP		Human	PMID:33565183
Biological Process	GO:0042573	retinoic acid metabolic process	Aldh1a2	IMP	MGI:MGI:1857891	Mouse	PMID:16368932
Biological Process	GO:0042573	retinoic acid metabolic process	Aldh1a2	IMP	MGI:MGI:2180721	Mouse	PMID:14623241
Biological Process	GO:0042573	retinoic acid metabolic process	Aldh1a2	IDA		Mouse	PMID:8797830
Biological Process	GO:0042573	retinoic acid metabolic process	Aldh1a2	IDA		Rat	PMID:12547725|RGD:1576367
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	Aldh1a2	IMP	MGI:MGI:2180721	Mouse	PMID:15739227
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	Aldh1a2	IGI	MGI:MGI:2679699	Mouse	PMID:17067568
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	Aldh1a2	IMP	MGI:MGI:1857891	Mouse	PMID:16806149
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	Aldh1a2	IGI	MGI:MGI:1096359	Mouse	PMID:17067568
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	aldh1a2	IMP	ZFIN:ZDB-MRPHLNO-050316-2	Zfish	PMID:22125274
Biological Process	GO:0090242	retinoic acid receptor signaling pathway involved in somitogenesis	Aldh1a2	IGI	MGI:MGI:1100864	Mouse	PMID:15889094
Biological Process	GO:0090242	retinoic acid receptor signaling pathway involved in somitogenesis	Aldh1a2	IMP	MGI:MGI:1857891	Mouse	PMID:15889094
Biological Process	GO:0042572	retinol metabolic process	aldh1a2	IGI	ZFIN:ZDB-MRPHLNO-050316-2,ZFIN:ZDB-MRPHLNO-070313-1	Zfish	PMID:17098734
Biological Process	GO:0001756	somitogenesis	aldh1a2	IMP	ZFIN:ZDB-MRPHLNO-050316-2	Zfish	PMID:24284210
Biological Process	GO:0001756	somitogenesis	aldh1a2	IGI	ZFIN:ZDB-MRPHLNO-050316-2,ZFIN:ZDB-MRPHLNO-060113-5	Zfish	PMID:24284210
Biological Process	GO:0035799	ureter maturation	Aldh1a2	IMP	MGI:MGI:1857891	Mouse	PMID:21521737

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern