Comparative GO Graph (mouse, human)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ALDH1A1
  • Mouse genes Aldh1a7
  • Rat genes Aldh1a7
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aldh1a7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity	Aldh1a7	IDA		Rat	PMID:2753900|RGD:631864
Molecular Function	GO:0106373	3-deoxyglucosone dehydrogenase activity	ALDH1A1	IDA		Human	PMID:17175089
Molecular Function	GO:0004029	aldehyde dehydrogenase (NAD+) activity	ALDH1A1	IDA		Human	PMID:12941160
Molecular Function	GO:0004029	aldehyde dehydrogenase (NAD+) activity	ALDH1A1	IMP		Human	PMID:15623782
Molecular Function	GO:0004029	aldehyde dehydrogenase (NAD+) activity	ALDH1A1	IDA		Human	PMID:23444097
Molecular Function	GO:0004029	aldehyde dehydrogenase (NAD+) activity	ALDH1A1	IDA		Human	PMID:25450233
Molecular Function	GO:0004029	aldehyde dehydrogenase (NAD+) activity	ALDH1A1	IDA		Human	PMID:4015840
Molecular Function	GO:0004029	aldehyde dehydrogenase (NAD+) activity	Aldh1a7	IDA		Rat	PMID:10998257|RGD:2306339
Molecular Function	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity	Aldh1a7	IDA		Rat	PMID:10998257|RGD:2306339
Molecular Function	GO:0042802	identical protein binding	Aldh1a7	IPI	RGD:620252	Rat	PMID:10998257|RGD:2306339
Molecular Function	GO:0005515	protein binding	ALDH1A1	IPI	UniProtKB:P09172	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ALDH1A1	IPI	UniProtKB:P14136	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ALDH1A1	IPI	UniProtKB:Q8WXH2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ALDH1A1	IPI	UniProtKB:O60678	Human	PMID:33495566
Cellular Component	GO:0005829	cytosol	ALDH1A1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	ALDH1A1	IDA		Human	PMID:12941160
Cellular Component	GO:0070062	extracellular exosome	ALDH1A1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	ALDH1A1	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	ALDH1A1	HDA		Human	PMID:23533145
Biological Process	GO:0110095	cellular detoxification of aldehyde	ALDH1A1	IMP		Human	PMID:15623782
Biological Process	GO:0030392	fructosamine catabolic process	ALDH1A1	IDA		Human	PMID:17175089
Biological Process	GO:0006001	fructose catabolic process	Aldh1a7	IDA		Mouse	PMID:4343087
Biological Process	GO:0006001	fructose catabolic process	Aldh1a7	IDA		Mouse	PMID:29414685
Biological Process	GO:0035106	operant conditioning	Aldh1a7	IEP		Rat	PMID:15720406|RGD:1357428

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern