Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ALDH1L1
  • Mouse genes Aldh1l1
  • Rat genes Aldh1l1
  • Zfish genes aldh1l1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aldh1l1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0033721	aldehyde dehydrogenase (NADP+) activity	Aldh1l1	IDA		Rat	PMID:17302434|RGD:8553346
Molecular Function	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	Aldh1l1	IDA		Rat	PMID:1848231|RGD:632027
Molecular Function	GO:0016155	formyltetrahydrofolate dehydrogenase activity	ALDH1L1	IDA		Human	PMID:19933275
Molecular Function	GO:0016155	formyltetrahydrofolate dehydrogenase activity	Aldh1l1	IMP		Mouse	MGI:MGI:6369507|PMID:31624291
Molecular Function	GO:0016155	formyltetrahydrofolate dehydrogenase activity	Aldh1l1	IMP		Rat	PMID:10585460|RGD:150521656
Molecular Function	GO:0016155	formyltetrahydrofolate dehydrogenase activity	Aldh1l1	IDA		Rat	PMID:1848231|RGD:632027
Molecular Function	GO:0016155	formyltetrahydrofolate dehydrogenase activity	aldh1l1	IDA		Zfish	PMID:25849409
Molecular Function	GO:0016155	formyltetrahydrofolate dehydrogenase activity	aldh1l1	IDA		Zfish	PMID:20381623
Molecular Function	GO:0016787	hydrolase activity	aldh1l1	IDA		Zfish	PMID:20381623
Molecular Function	GO:0005515	protein binding	Aldh1l1	IPI	PR:E9Q9D5	Mouse	PMID:23055941
Molecular Function	GO:0044877	protein-containing complex binding	Aldh1l1	IDA		Rat	PMID:17669278|RGD:2303511
Cellular Component	GO:0005829	cytosol	ALDH1L1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Aldh1l1	IDA		Rat	PMID:1848231|RGD:632027
Cellular Component	GO:0070062	extracellular exosome	ALDH1L1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	ALDH1L1	HDA		Human	PMID:23533145
Cellular Component	GO:0005739	mitochondrion	Aldh1l1	HDA		Mouse	PMID:18614015
Cellular Component	GO:0032991	protein-containing complex	Aldh1l1	IDA		Rat	PMID:17669278|RGD:2303511
Biological Process	GO:0009258	10-formyltetrahydrofolate catabolic process	ALDH1L1	IDA		Human	PMID:19933275
Biological Process	GO:0009258	10-formyltetrahydrofolate catabolic process	Aldh1l1	IMP		Mouse	MGI:MGI:6369507|PMID:31624291
Biological Process	GO:0009258	10-formyltetrahydrofolate catabolic process	Aldh1l1	IMP		Rat	PMID:10585460|RGD:150521656
Biological Process	GO:0009258	10-formyltetrahydrofolate catabolic process	Aldh1l1	IDA		Rat	PMID:1848231|RGD:632027
Biological Process	GO:0038183	bile acid signaling pathway	Aldh1l1	IEP		Rat	PMID:30223280|RGD:15045612
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	aldh1l1	IMP	ZFIN:ZDB-MRPHLNO-140710-2	Zfish	PMID:24747731
Biological Process	GO:0046655	folic acid metabolic process	Aldh1l1	IDA		Rat	PMID:1848231|RGD:632027
Biological Process	GO:0007369	gastrulation	aldh1l1	IMP	ZFIN:ZDB-MRPHLNO-140710-2	Zfish	PMID:24747731
Biological Process	GO:0007369	gastrulation	aldh1l1	IMP	ZFIN:ZDB-MRPHLNO-140710-1	Zfish	PMID:24747731
Biological Process	GO:0007507	heart development	aldh1l1	IMP	ZFIN:ZDB-MRPHLNO-140710-2	Zfish	PMID:24747731
Biological Process	GO:0006740	NADPH regeneration	ALDH1L1	IDA		Human	PMID:19933275
Biological Process	GO:0006740	NADPH regeneration	Aldh1l1	IDA		Rat	PMID:1848231|RGD:632027
Biological Process	GO:0001755	neural crest cell migration	aldh1l1	IMP	ZFIN:ZDB-MRPHLNO-140710-1	Zfish	PMID:24747731
Biological Process	GO:0001755	neural crest cell migration	aldh1l1	IMP	ZFIN:ZDB-MRPHLNO-140710-2	Zfish	PMID:24747731
Biological Process	GO:0048885	neuromast deposition	aldh1l1	IMP	ZFIN:ZDB-MRPHLNO-140710-2	Zfish	PMID:24747731

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern