Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ALDH3A2
  • Mouse genes Aldh3a2
  • Rat genes Aldh3a2
  • Zfish genes aldh3a1,aldh3a2a,aldh3a2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aldh3a2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity	Aldh3a2	IDA		Rat	PMID:1717467|RGD:61536
Molecular Function	GO:0004029	aldehyde dehydrogenase (NAD+) activity	ALDH3A2	IMP		Human	PMID:15110319
Molecular Function	GO:0004029	aldehyde dehydrogenase (NAD+) activity	ALDH3A2	IMP		Human	PMID:8528251
Molecular Function	GO:0004029	aldehyde dehydrogenase (NAD+) activity	ALDH3A2	IDA		Human	PMID:9133646
Molecular Function	GO:0004029	aldehyde dehydrogenase (NAD+) activity	Aldh3a2	IDA		Mouse	PMID:25286108
Molecular Function	GO:0046577	long-chain-alcohol oxidase activity	ALDH3A2	IDA		Human	PMID:18035827
Molecular Function	GO:0050061	long-chain-aldehyde dehydrogenase activity	ALDH3A2	IDA		Human	PMID:25047030
Molecular Function	GO:0052814	medium-chain-aldehyde dehydrogenase activity	ALDH3A2	IDA		Human	PMID:25047030
Molecular Function	GO:0005515	protein binding	ALDH3A2	IPI	UniProtKB:P51648	Human	PMID:25047030
Molecular Function	GO:0042803	protein homodimerization activity	ALDH3A2	IPI	UniProtKB:P51648	Human	PMID:25047030
Cellular Component	GO:0005829	cytosol	Aldh3a2	IDA		Rat	PMID:1453005|RGD:1357171
Cellular Component	GO:0005783	endoplasmic reticulum	Aldh3a2	IDA		Mouse	MGI:MGI:3718860|PMID:17510064
Cellular Component	GO:0005783	endoplasmic reticulum	Aldh3a2	IDA		Rat	PMID:14561759|RGD:1580664
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Aldh3a2	IDA		Rat	PMID:1717467|RGD:61536
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ALDH3A2	IDA		Human	PMID:9133646
Cellular Component	GO:0016020	membrane	Aldh3a2	IDA		Mouse	PMID:25286108
Cellular Component	GO:0005743	mitochondrial inner membrane	Aldh3a2	HDA		Mouse	PMID:12865426
Cellular Component	GO:0005739	mitochondrion	Aldh3a2	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005634	nucleus	Aldh3a2	IDA		Rat	PMID:1453005|RGD:1357171
Biological Process	GO:0006081	cellular aldehyde metabolic process	ALDH3A2	IDA		Human	PMID:9133646
Biological Process	GO:0007417	central nervous system development	ALDH3A2	IMP		Human	PMID:8528251
Biological Process	GO:0008544	epidermis development	ALDH3A2	IMP		Human	PMID:8528251
Biological Process	GO:0046292	formaldehyde metabolic process	Aldh3a2	IDA		Rat	PMID:1453005|RGD:1357171
Biological Process	GO:0042593	glucose homeostasis	aldh3a1	IMP	ZFIN:ZDB-GENO-220811-4	Zfish	PMID:32980661
Biological Process	GO:0046458	hexadecanal metabolic process	ALDH3A2	IDA		Human	PMID:25047030
Biological Process	GO:0007422	peripheral nervous system development	ALDH3A2	IMP		Human	PMID:8528251
Biological Process	GO:0033306	phytol metabolic process	ALDH3A2	IMP		Human	PMID:15110319
Biological Process	GO:0000302	response to reactive oxygen species	Aldh3a2	IDA		Rat	PMID:14638678|RGD:1304463

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern