Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ALDH6A1
  • Mouse genes Aldh6a1
  • Rat genes Aldh6a1
  • Zfish genes aldh6a1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aldh6a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0018478	malonate-semialdehyde dehydrogenase (acetylating) activity	Aldh6a1	IDA		Rat	PMID:2768248|RGD:1599052
Molecular Function	GO:0004491	methylmalonate-semialdehyde dehydrogenase (acylating) activity	ALDH6A1	IMP		Human	PMID:23835272
Molecular Function	GO:0004491	methylmalonate-semialdehyde dehydrogenase (acylating) activity	Aldh6a1	IDA		Rat	PMID:2768248|RGD:1599052
Molecular Function	GO:0003723	RNA binding	ALDH6A1	HDA		Human	PMID:22658674
Molecular Function	GO:0016790	thiolester hydrolase activity	Aldh6a1	IDA		Rat	PMID:1540637|RGD:1599062
Cellular Component	GO:0005739	mitochondrion	ALDH6A1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Aldh6a1	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Aldh6a1	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005654	nucleoplasm	ALDH6A1	IDA		Human	GO_REF:0000052
Biological Process	GO:0019484	beta-alanine catabolic process	Aldh6a1	IDA		Rat	PMID:2768248|RGD:1599052
Biological Process	GO:0050873	brown fat cell differentiation	Aldh6a1	IDA		Mouse	PMID:18492766
Biological Process	GO:0006210	thymine catabolic process	ALDH6A1	IMP		Human	PMID:23835272
Biological Process	GO:0006210	thymine catabolic process	Aldh6a1	IDA		Rat	PMID:2768248|RGD:1599052
Biological Process	GO:0019859	thymine metabolic process	Aldh6a1	IDA		Rat	PMID:2768248|RGD:1599052
Biological Process	GO:0006574	valine catabolic process	ALDH6A1	IMP		Human	PMID:23835272
Biological Process	GO:0006574	valine catabolic process	Aldh6a1	IDA		Rat	PMID:2768248|RGD:1599052
Biological Process	GO:0006573	valine metabolic process	Aldh6a1	IDA		Rat	PMID:2768248|RGD:1599052

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern