Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ALDOA
  • Mouse genes Aldoa
  • Rat genes Aldoa
  • Zfish genes aldoab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aldoa

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	ALDOA	HDA		Human	PMID:25468996
Molecular Function	GO:0008092	cytoskeletal protein binding	ALDOA	IDA		Human	PMID:9244396
Molecular Function	GO:0070061	fructose binding	ALDOA	IDA		Human	PMID:10048322
Molecular Function	GO:0070061	fructose binding	ALDOA	IDA		Human	PMID:14766013
Molecular Function	GO:0004332	fructose-bisphosphate aldolase activity	ALDOA	IDA		Human	PMID:14766013
Molecular Function	GO:0004332	fructose-bisphosphate aldolase activity	ALDOA	IDA		Human	PMID:9244396
Molecular Function	GO:0004332	fructose-bisphosphate aldolase activity	Aldoa	IMP		Mouse	MGI:MGI:6101994|PMID:23495010
Molecular Function	GO:0004332	fructose-bisphosphate aldolase activity	Aldoa	IDA		Mouse	PMID:11785984
Molecular Function	GO:0004332	fructose-bisphosphate aldolase activity	Aldoa	IGI	MGI:MGI:87995	Mouse	PMID:25637246
Molecular Function	GO:0042802	identical protein binding	ALDOA	IPI	UniProtKB:P04075	Human	PMID:10944123
Molecular Function	GO:0042802	identical protein binding	ALDOA	IPI	UniProtKB:P04075	Human	PMID:21988832
Molecular Function	GO:0002020	protease binding	Aldoa	IPI	UniProtKB:P16259	Mouse	MGI:MGI:3811664|PMID:18676612
Molecular Function	GO:0005515	protein binding	ALDOA	IPI	UniProtKB:P12004	Human	PMID:20849852
Molecular Function	GO:0005515	protein binding	ALDOA	IPI	UniProtKB:Q12836	Human	PMID:23355646
Molecular Function	GO:0005515	protein binding	ALDOA	IPI	UniProtKB:P09972	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	ALDOA	IPI	UniProtKB:P09972	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	ALDOA	IPI	UniProtKB:P09972	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	Aldoa	IPI	UniProtKB:Q80Z30	Rat	PMID:15680915|RGD:8553307
Molecular Function	GO:0003723	RNA binding	ALDOA	HDA		Human	PMID:22681889
Cellular Component	GO:0015629	actin cytoskeleton	ALDOA	IDA		Human	PMID:9244396
Cellular Component	GO:0005737	cytoplasm	Aldoa	IDA		Mouse	PMID:18698006
Cellular Component	GO:0005737	cytoplasm	Aldoa	IDA		Rat	PMID:19081846|RGD:10679992
Cellular Component	GO:0005737	cytoplasm	Aldoa	IDA		Rat	PMID:201371|RGD:2302783
Cellular Component	GO:0005829	cytosol	Aldoa	IDA		Mouse	PMID:26080680
Cellular Component	GO:0070062	extracellular exosome	ALDOA	HDA		Human	PMID:12519789
Cellular Component	GO:0070062	extracellular exosome	ALDOA	IDA		Human	PMID:17641064
Cellular Component	GO:0070062	extracellular exosome	ALDOA	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	ALDOA	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	ALDOA	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	ALDOA	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	ALDOA	HDA		Human	PMID:23580065
Cellular Component	GO:0005615	extracellular space	Aldoa	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0000792	heterochromatin	Aldoa	IDA		Rat	PMID:19081846|RGD:10679992
Cellular Component	GO:0016020	membrane	ALDOA	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	Aldoa	IDA		Mouse	MGI:MGI:3811664|PMID:18676612
Cellular Component	GO:0005739	mitochondrion	Aldoa	IDA		Rat	PMID:18384645|RGD:2302079
Cellular Component	GO:0043209	myelin sheath	Aldoa	HDA		Mouse	MGI:MGI:3834050|PMID:17634366
Cellular Component	GO:0005634	nucleus	ALDOA	HDA		Human	PMID:21630459
Cellular Component	GO:0005886	plasma membrane	Aldoa	IDA		Mouse	PMID:18698006
Cellular Component	GO:0032991	protein-containing complex	Aldoa	IDA		Mouse	MGI:MGI:3811664|PMID:18676612
Cellular Component	GO:0035686	sperm fibrous sheath	Aldoa	IDA		Mouse	PMID:16687649
Cellular Component	GO:0035686	sperm fibrous sheath	Aldoa	IDA		Mouse	PMID:17659271
Cellular Component	GO:0061827	sperm head	ALDOA	IDA		Human	PMID:23355646
Cellular Component	GO:0030018	Z disc	Aldoa	IDA		Mouse	MGI:MGI:3811664|PMID:18676612
Biological Process	GO:0006754	ATP biosynthetic process	ALDOA	IMP		Human	PMID:14615364
Biological Process	GO:0007339	binding of sperm to zona pellucida	ALDOA	IMP		Human	PMID:23355646
Biological Process	GO:0061621	canonical glycolysis	Aldoa	IDA		Mouse	PMID:28049690
Biological Process	GO:0030388	fructose 1,6-bisphosphate metabolic process	ALDOA	IDA		Human	PMID:14766013
Biological Process	GO:0030388	fructose 1,6-bisphosphate metabolic process	ALDOA	IDA		Human	PMID:9244396
Biological Process	GO:0006000	fructose metabolic process	ALDOA	IMP		Human	PMID:14615364
Biological Process	GO:0006096	glycolytic process	ALDOA	IMP		Human	PMID:14615364
Biological Process	GO:0019242	methylglyoxal biosynthetic process	Aldoa	IMP		Rat	PMID:21890532|RGD:13673877
Biological Process	GO:0046716	muscle cell cellular homeostasis	ALDOA	IMP		Human	PMID:14615364
Biological Process	GO:0030335	positive regulation of cell migration	Aldoa	IMP		Mouse	MGI:MGI:6101994|PMID:23495010
Biological Process	GO:0008360	regulation of cell shape	ALDOA	IDA		Human	PMID:9244396
Biological Process	GO:0043627	response to estrogen	Aldoa	IEP		Rat	PMID:16339744|RGD:1599058
Biological Process	GO:0009408	response to heat	Aldoa	IEP		Rat	PMID:10395295|RGD:1599061
Biological Process	GO:0001666	response to hypoxia	Aldoa	IEP		Rat	PMID:16930621|RGD:1599054
Biological Process	GO:0032496	response to lipopolysaccharide	Aldoa	IEP		Rat	PMID:16930621|RGD:1599054
Biological Process	GO:0035094	response to nicotine	Aldoa	IEP		Rat	PMID:16622831|RGD:1599057
Biological Process	GO:0006941	striated muscle contraction	ALDOA	IMP		Human	PMID:14615364

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern