Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ALKBH1
  • Mouse genes Alkbh1
  • Rat genes Alkbh1
  • Zfish genes alkbh1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Alkbh1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016706	2-oxoglutarate-dependent dioxygenase activity	ALKBH1	IDA		Human	PMID:27497299
Molecular Function	GO:0042056	chemoattractant activity	Alkbh1	IDA		Mouse	PMID:16860792
Molecular Function	GO:0140078	class I DNA-(apurinic or apyrimidinic site) endonuclease activity	ALKBH1	IDA		Human	PMID:19959401
Molecular Function	GO:0008198	ferrous iron binding	ALKBH1	IDA		Human	PMID:18603530
Molecular Function	GO:0070579	methylcytosine dioxygenase activity	ALKBH1	IDA		Human	PMID:18603530
Molecular Function	GO:0035516	oxidative DNA demethylase activity	ALKBH1	IDA		Human	PMID:30017583
Molecular Function	GO:0035516	oxidative DNA demethylase activity	ALKBH1	IDA		Human	PMID:30392959
Molecular Function	GO:0035516	oxidative DNA demethylase activity	Alkbh1	IDA		Mouse	MGI:MGI:6316531|PMID:27027282
Molecular Function	GO:0035515	oxidative RNA demethylase activity	ALKBH1	IDA		Human	PMID:31188562
Molecular Function	GO:0005515	protein binding	Alkbh1	IPI	PR:O54946	Mouse	PMID:18163532
Molecular Function	GO:0000049	tRNA binding	ALKBH1	IDA		Human	PMID:27497299
Molecular Function	GO:1990984	tRNA demethylase activity	ALKBH1	IDA		Human	PMID:27745969
Cellular Component	GO:0005783	endoplasmic reticulum	ALKBH1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000791	euchromatin	Alkbh1	IDA		Mouse	PMID:18163532
Cellular Component	GO:0005739	mitochondrion	ALKBH1	IDA		Human	PMID:18603530
Cellular Component	GO:0005739	mitochondrion	ALKBH1	IDA		Human	PMID:27497299
Cellular Component	GO:0005654	nucleoplasm	ALKBH1	IDA		Human	GO_REF:0000052
Biological Process	GO:0030154	cell differentiation	Alkbh1	IMP	MGI:MGI:3774031	Mouse	PMID:18163532
Biological Process	GO:0048589	developmental growth	Alkbh1	IMP	MGI:MGI:3774031	Mouse	PMID:18163532
Biological Process	GO:0006307	DNA dealkylation involved in DNA repair	ALKBH1	IDA		Human	PMID:18603530
Biological Process	GO:0080111	DNA demethylation	ALKBH1	IDA		Human	PMID:18603530
Biological Process	GO:0080111	DNA demethylation	ALKBH1	IDA		Human	PMID:30017583
Biological Process	GO:0080111	DNA demethylation	ALKBH1	IDA		Human	PMID:30392959
Biological Process	GO:0080111	DNA demethylation	Alkbh1	IDA		Mouse	MGI:MGI:6316531|PMID:27027282
Biological Process	GO:0006281	DNA repair	ALKBH1	IDA		Human	PMID:18603530
Biological Process	GO:0006281	DNA repair	ALKBH1	IDA		Human	PMID:19959401
Biological Process	GO:0001701	in utero embryonic development	Alkbh1	IMP	MGI:MGI:3774031	Mouse	PMID:18163532
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Alkbh1	IDA		Mouse	PMID:16860792
Biological Process	GO:0001764	neuron migration	Alkbh1	IDA		Mouse	PMID:16860792
Biological Process	GO:0031175	neuron projection development	Alkbh1	IDA		Mouse	PMID:16860792
Biological Process	GO:0070989	oxidative demethylation	ALKBH1	IDA		Human	PMID:18603530
Biological Process	GO:0035513	oxidative RNA demethylation	ALKBH1	IDA		Human	PMID:31188562
Biological Process	GO:0001890	placenta development	Alkbh1	IMP	MGI:MGI:3774031	Mouse	PMID:18163532
Biological Process	GO:0010468	regulation of gene expression	Alkbh1	IMP	MGI:MGI:3774031	Mouse	PMID:18163532
Biological Process	GO:0070129	regulation of mitochondrial translation	ALKBH1	IMP		Human	PMID:27497299
Biological Process	GO:0006448	regulation of translational elongation	ALKBH1	IMP		Human	PMID:27745969
Biological Process	GO:0006446	regulation of translational initiation	ALKBH1	IMP		Human	PMID:27745969
Biological Process	GO:0042245	RNA repair	ALKBH1	IDA		Human	PMID:18603530
Biological Process	GO:1990983	tRNA demethylation	ALKBH1	IDA		Human	PMID:27745969
Biological Process	GO:1990983	tRNA demethylation	Alkbh1	IMP		Mouse	MGI:MGI:6316585|PMID:27745969
Biological Process	GO:0002101	tRNA wobble cytosine modification	ALKBH1	IDA		Human	PMID:27497299

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern