Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ALKBH4
  • Mouse genes Alkbh4
  • Rat genes Alkbh4
  • Zfish genes alkbh4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Alkbh4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016706	2-oxoglutarate-dependent dioxygenase activity	ALKBH4	IDA		Human	PMID:21166655
Molecular Function	GO:0003779	actin binding	ALKBH4	IDA		Human	PMID:23673617
Molecular Function	GO:0035516	oxidative DNA demethylase activity	Alkbh4	IDA		Mouse	MGI:MGI:6323482|PMID:30982744
Molecular Function	GO:0005515	protein binding	ALKBH4	IPI	UniProtKB:Q86UW9	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	ALKBH4	IPI	UniProtKB:P42568	Human	PMID:23145062
Molecular Function	GO:0005515	protein binding	ALKBH4	IPI	UniProtKB:Q09472	Human	PMID:23145062
Molecular Function	GO:0005515	protein binding	ALKBH4	IPI	UniProtKB:Q86UW9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ALKBH4	IPI	UniProtKB:Q9BUZ4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ALKBH4	IPI	UniProtKB:Q86UW9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	ALKBH4	IPI	UniProtKB:Q9BUZ4	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	ALKBH4	IPI	UniProtKB:P15884-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALKBH4	IPI	UniProtKB:P42568	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALKBH4	IPI	UniProtKB:P80188	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALKBH4	IPI	UniProtKB:Q86UW9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALKBH4	IPI	UniProtKB:Q92567-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALKBH4	IPI	UniProtKB:Q9GZT8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALKBH4	IPI	UniProtKB:Q9H8Y8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALKBH4	IPI	UniProtKB:Q9NP55	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALKBH4	IPI	UniProtKB:Q9NX01	Human	PMID:32296183
Cellular Component	GO:0070938	contractile ring	ALKBH4	IDA		Human	PMID:23673617
Cellular Component	GO:0030496	midbody	ALKBH4	IDA		Human	PMID:23673617
Biological Process	GO:0031032	actomyosin structure organization	ALKBH4	IMP		Human	PMID:23673617
Biological Process	GO:0036090	cleavage furrow ingression	ALKBH4	IMP		Human	PMID:23673617
Biological Process	GO:0080111	DNA demethylation	Alkbh4	IDA		Mouse	MGI:MGI:6323482|PMID:30982744
Biological Process	GO:0006482	protein demethylation	ALKBH4	IDA		Human	PMID:23673617
Biological Process	GO:0110020	regulation of actomyosin structure organization	alkbh4	IMP	ZFIN:ZDB-GENO-190604-4	Zfish	PMID:28924386
Biological Process	GO:0110020	regulation of actomyosin structure organization	alkbh4	IMP	ZFIN:ZDB-GENO-190604-3	Zfish	PMID:28924386
Biological Process	GO:0110020	regulation of actomyosin structure organization	alkbh4	IGI	ZFIN:ZDB-GENE-090312-21	Zfish	PMID:28924386
Biological Process	GO:0110020	regulation of actomyosin structure organization	alkbh4	IGI	ZFIN:ZDB-GENO-190604-14	Zfish	PMID:28924386
Biological Process	GO:1902275	regulation of chromatin organization	Alkbh4	IDA		Mouse	MGI:MGI:6323482|PMID:30982744

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern