Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ALKBH8
  • Mouse genes Alkbh8
  • Rat genes Alkbh8
  • Zfish genes alkbh8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Alkbh8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005506	iron ion binding	Alkbh8	IDA		Mouse	MGI:MGI:5607402|PMID:20583019
Molecular Function	GO:0005515	protein binding	ALKBH8	IPI	UniProtKB:Q9UI30	Human	PMID:20123966
Molecular Function	GO:0005515	protein binding	ALKBH8	IPI	UniProtKB:Q9UI30	Human	PMID:20308323
Molecular Function	GO:0005515	protein binding	ALKBH8	IPI	UniProtKB:Q9UI30	Human	PMID:34948388
Molecular Function	GO:0106335	tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity	Alkbh8	IDA		Mouse	PMID:20583019
Molecular Function	GO:0016300	tRNA (uracil) methyltransferase activity	ALKBH8	IDA		Human	PMID:20308323
Molecular Function	GO:0016300	tRNA (uracil) methyltransferase activity	Alkbh8	IMP		Mouse	MGI:MGI:4461096|PMID:20123966
Molecular Function	GO:0000049	tRNA binding	ALKBH8	IDA		Human	PMID:22065580
Molecular Function	GO:0008270	zinc ion binding	ALKBH8	IDA		Human	PMID:22065580
Cellular Component	GO:0005737	cytoplasm	ALKBH8	IDA		Human	PMID:34948388
Cellular Component	GO:0005829	cytosol	ALKBH8	IDA		Human	PMID:20308323
Cellular Component	GO:0005654	nucleoplasm	ALKBH8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ALKBH8	IDA		Human	PMID:20308323
Biological Process	GO:0006974	DNA damage response	ALKBH8	IDA		Human	PMID:20308323
Biological Process	GO:0030488	tRNA methylation	ALKBH8	IDA		Human	PMID:20308323
Biological Process	GO:0030488	tRNA methylation	ALKBH8	IMP		Human	PMID:31079898
Biological Process	GO:0030488	tRNA methylation	Alkbh8	IMP		Mouse	MGI:MGI:4461096|PMID:20123966
Biological Process	GO:0002098	tRNA wobble uridine modification	ALKBH8	IDA		Human	PMID:21285950
Biological Process	GO:0002098	tRNA wobble uridine modification	ALKBH8	IMP		Human	PMID:31079898
Biological Process	GO:0002098	tRNA wobble uridine modification	Alkbh8	IDA		Mouse	MGI:MGI:5607402|PMID:20583019

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern