Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ALMS1
  • Mouse genes Alms1
  • Rat genes Alms1
  • Zfish genes alms1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Alms1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051393	alpha-actinin binding	Alms1	IPI	PR:P57780	Mouse	PMID:22693585
Molecular Function	GO:0051393	alpha-actinin binding	Alms1	IPI	PR:Q7TPR4	Mouse	PMID:22693585
Molecular Function	GO:0051393	alpha-actinin binding	Alms1	IPI	PR:O88990	Mouse	PMID:22693585
Molecular Function	GO:0051393	alpha-actinin binding	Alms1	IPI	PR:Q9JI91	Mouse	PMID:22693585
Molecular Function	GO:0005515	protein binding	Alms1	IPI	UniProtKB:P57780|UniProtKB:Q7TPR4|UniProtKB:Q9D753	Mouse	MGI:MGI:5436381|PMID:22693585
Cellular Component	GO:0005814	centriole	ALMS1	IDA		Human	PMID:20844083
Cellular Component	GO:0005814	centriole	Alms1	IDA		Rat	PMID:21071598|RGD:8696019
Cellular Component	GO:0005813	centrosome	ALMS1	IDA		Human	PMID:15855349
Cellular Component	GO:0005813	centrosome	ALMS1	IDA		Human	PMID:21399614
Cellular Component	GO:0036064	ciliary basal body	Alms1	IDA		Rat	PMID:21071598|RGD:8696019
Biological Process	GO:0009887	animal organ morphogenesis	alms1	IMP	ZFIN:ZDB-GENO-200316-9	Zfish	PMID:31220269
Biological Process	GO:0006915	apoptotic process	Alms1	IMP	MGI:MGI:3699224	Mouse	PMID:17206865
Biological Process	GO:0019722	calcium-mediated signaling	Alms1	IMP		Mouse	PMID:17206865
Biological Process	GO:0042632	cholesterol homeostasis	Alms1	IMP	MGI:MGI:3699224	Mouse	PMID:17206865
Biological Process	GO:0060271	cilium assembly	Alms1	IMP	MGI:MGI:3699224	Mouse	PMID:17206865
Biological Process	GO:0060271	cilium assembly	Alms1	IMP		Mouse	PMID:17206865
Biological Process	GO:0016197	endosomal transport	ALMS1	IMP		Human	PMID:22693585
Biological Process	GO:1904019	epithelial cell apoptotic process	Alms1	IMP	MGI:MGI:3699224	Mouse	PMID:17206865
Biological Process	GO:0050673	epithelial cell proliferation	Alms1	IMP	MGI:MGI:3699224	Mouse	PMID:17206865
Biological Process	GO:0001736	establishment of planar polarity	Alms1	IMP	MGI:MGI:3576051	Mouse	PMID:21071598
Biological Process	GO:0042593	glucose homeostasis	Alms1	IMP	MGI:MGI:3576051	Mouse	PMID:16000322
Biological Process	GO:0042593	glucose homeostasis	Alms1	IMP	MGI:MGI:3621984	Mouse	PMID:16513793
Biological Process	GO:0046323	glucose import	alms1	IMP	ZFIN:ZDB-GENO-200316-10	Zfish	PMID:31220269
Biological Process	GO:0060122	inner ear receptor cell stereocilium organization	Alms1	IMP	MGI:MGI:3576051	Mouse	PMID:21071598
Biological Process	GO:0006629	lipid metabolic process	Alms1	IMP	MGI:MGI:3576051	Mouse	PMID:16000322
Biological Process	GO:1904036	negative regulation of epithelial cell apoptotic process	Alms1	IMP	MGI:MGI:3699224	Mouse	PMID:17206865
Biological Process	GO:0040015	negative regulation of multicellular organism growth	Alms1	IMP	MGI:MGI:3621984	Mouse	PMID:16513793
Biological Process	GO:0030728	ovulation	Alms1	IMP	MGI:MGI:3621984	Mouse	PMID:16513793
Biological Process	GO:1990798	pancreas regeneration	alms1	IMP	ZFIN:ZDB-MRPHLNO-160310-5	Zfish	PMID:26494903
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Alms1	IMP		Mouse	MGI:MGI:6316940|PMID:27803297
Biological Process	GO:0045807	positive regulation of endocytosis	Alms1	IMP		Rat	PMID:30385718|RGD:151361229
Biological Process	GO:0045598	regulation of fat cell differentiation	Alms1	IMP	MGI:MGI:3699224	Mouse	PMID:17206865
Biological Process	GO:0045598	regulation of fat cell differentiation	Alms1	IMP	MGI:MGI:3576051	Mouse	PMID:16000322
Biological Process	GO:0051492	regulation of stress fiber assembly	ALMS1	IMP		Human	PMID:22693585
Biological Process	GO:0046548	retinal rod cell development	Alms1	IMP	MGI:MGI:3576051	Mouse	PMID:16000322
Biological Process	GO:0007605	sensory perception of sound	Alms1	IMP	MGI:MGI:3621984	Mouse	PMID:16513793
Biological Process	GO:0007605	sensory perception of sound	Alms1	IMP	MGI:MGI:3576051	Mouse	PMID:21071598
Biological Process	GO:0007605	sensory perception of sound	Alms1	IMP	MGI:MGI:3576051	Mouse	PMID:16000322
Biological Process	GO:0007286	spermatid development	Alms1	IMP	MGI:MGI:3699224	Mouse	PMID:17206865
Biological Process	GO:0007286	spermatid development	Alms1	IMP	MGI:MGI:3621984	Mouse	PMID:16513793
Biological Process	GO:0044342	type B pancreatic cell proliferation	alms1	IMP	ZFIN:ZDB-MRPHLNO-160310-5	Zfish	PMID:26494903

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern