Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ALOXE3
  • Mouse genes Aloxe3
  • Rat genes Aloxe3
  • Zfish genes si:dkey-17e16.9
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aloxe3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051120	hepoxilin A3 synthase activity	ALOXE3	IDA		Human	PMID:12881489
Molecular Function	GO:0051120	hepoxilin A3 synthase activity	ALOXE3	IDA		Human	PMID:17045234
Molecular Function	GO:0051120	hepoxilin A3 synthase activity	Aloxe3	IDA		Mouse	MGI:MGI:3694035|PMID:17045234
Molecular Function	GO:0050486	intramolecular transferase activity, transferring hydroxy groups	ALOXE3	IDA		Human	PMID:20923767
Molecular Function	GO:0050486	intramolecular transferase activity, transferring hydroxy groups	ALOXE3	IDA		Human	PMID:21558561
Molecular Function	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	ALOXE3	IDA		Human	PMID:20921226
Molecular Function	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	ALOXE3	IDA		Human	PMID:20923767
Molecular Function	GO:0005515	protein binding	ALOXE3	IPI	UniProtKB:P25490	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALOXE3	IPI	UniProtKB:P36508	Human	PMID:32296183
Biological Process	GO:0019369	arachidonic acid metabolic process	ALOXE3	IDA		Human	PMID:12881489
Biological Process	GO:0019369	arachidonic acid metabolic process	ALOXE3	IDA		Human	PMID:17045234
Biological Process	GO:0019369	arachidonic acid metabolic process	Aloxe3	IDA		Mouse	MGI:MGI:3694035|PMID:17045234
Biological Process	GO:0019369	arachidonic acid metabolic process	Aloxe3	IDA		Rat	PMID:23382512|RGD:8554649
Biological Process	GO:0046513	ceramide biosynthetic process	Aloxe3	IMP		Mouse	MGI:MGI:5488571|PMID:22832496
Biological Process	GO:0061436	establishment of skin barrier	Aloxe3	IMP		Mouse	MGI:MGI:5488571|PMID:22832496
Biological Process	GO:0045444	fat cell differentiation	Aloxe3	IMP		Mouse	MGI:MGI:4819891|PMID:20530198
Biological Process	GO:0051122	hepoxilin biosynthetic process	ALOXE3	IDA		Human	PMID:12881489
Biological Process	GO:0051122	hepoxilin biosynthetic process	ALOXE3	IDA		Human	PMID:17045234
Biological Process	GO:0051122	hepoxilin biosynthetic process	Aloxe3	IDA		Mouse	MGI:MGI:3694035|PMID:17045234
Biological Process	GO:0051122	hepoxilin biosynthetic process	Aloxe3	IMP		Mouse	MGI:MGI:5488571|PMID:22832496
Biological Process	GO:0051122	hepoxilin biosynthetic process	Aloxe3	IDA		Rat	PMID:23382512|RGD:8554649
Biological Process	GO:0043651	linoleic acid metabolic process	ALOXE3	IDA		Human	PMID:12881489
Biological Process	GO:0043651	linoleic acid metabolic process	ALOXE3	IDA		Human	PMID:17045234
Biological Process	GO:0043651	linoleic acid metabolic process	Aloxe3	IDA		Mouse	MGI:MGI:3694035|PMID:17045234
Biological Process	GO:0019372	lipoxygenase pathway	ALOXE3	IDA		Human	PMID:20921226
Biological Process	GO:0035357	peroxisome proliferator activated receptor signaling pathway	Aloxe3	IMP		Mouse	MGI:MGI:4819891|PMID:20530198
Biological Process	GO:0019233	sensory perception of pain	Aloxe3	IMP		Rat	PMID:23382512|RGD:8554649
Biological Process	GO:0006665	sphingolipid metabolic process	ALOXE3	IDA		Human	PMID:21558561

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern