Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ALPG,ALPI,ALPP
  • Mouse genes Alpi
  • Rat genes Alpi
  • Zfish genes alpi.1,alpi.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Alpi

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004035	alkaline phosphatase activity	ALPP	IDA		Human	PMID:1939159
Molecular Function	GO:0004035	alkaline phosphatase activity	ALPP	IDA		Human	PMID:2017684
Molecular Function	GO:0004035	alkaline phosphatase activity	ALPP	IDA		Human	PMID:2133555
Molecular Function	GO:0004035	alkaline phosphatase activity	ALPG	IDA		Human	PMID:1939159
Molecular Function	GO:0004035	alkaline phosphatase activity	Alpi	IDA		Rat	PMID:15885097|RGD:2300084
Molecular Function	GO:0004035	alkaline phosphatase activity	Alpi	IDA		Rat	PMID:24076154|RGD:8553411
Molecular Function	GO:0004035	alkaline phosphatase activity	Alpi	IDA		Rat	PMID:7744844|RGD:2300082
Molecular Function	GO:0000287	magnesium ion binding	Alpi	IDA		Rat	PMID:15885097|RGD:2300084
Molecular Function	GO:0000287	magnesium ion binding	Alpi	IDA		Rat	PMID:24076154|RGD:8553411
Molecular Function	GO:0002020	protease binding	ALPI	IPI	UniProtKB:P80067	Human	PMID:18307834
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:P26371	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:Q9BQ66	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:O15499	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:O76081-6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:P0DPK4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:P22735	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:P24592	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:P26371	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:P32242	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:P42830	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:P49639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:P49795	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:P49901	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:P57678	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:P60410	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:Q02930-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:Q07627	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:Q12837	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:Q5T5A8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:Q5T5B0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:Q5T752	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:Q5T753	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:Q5T754	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:Q5T871	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:Q5TA76	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:Q5TA77	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:Q5TA81	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:Q5TCM9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:Q6UY14-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:Q8IUG1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:Q92570	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:Q9BYE3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:Q9NWN3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPP	IPI	UniProtKB:Q9UGL9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ALPI	IPI	UniProtKB:P60410	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ALPI	IPI	UniProtKB:P60411	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ALPI	IPI	UniProtKB:Q7Z3S9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ALPI	IPI	UniProtKB:Q7Z3S9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	Alpi	IPI	UniProtKB:P15693	Rat	PMID:24076154|RGD:8553411
Molecular Function	GO:0042803	protein homodimerization activity	Alpi	IPI	UniProtKB:P15693	Rat	PMID:24076154|RGD:8553411
Molecular Function	GO:0008270	zinc ion binding	Alpi	IDA		Rat	PMID:15885097|RGD:2300084
Molecular Function	GO:0008270	zinc ion binding	Alpi	IDA		Rat	PMID:24076154|RGD:8553411
Cellular Component	GO:0009986	cell surface	ALPP	IDA		Human	PMID:15907827
Cellular Component	GO:0009897	external side of plasma membrane	Alpi	IDA		Rat	PMID:7744844|RGD:2300082
Cellular Component	GO:0005886	plasma membrane	ALPP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ALPI	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ALPG	IDA		Human	GO_REF:0000052
Biological Process	GO:0071773	cellular response to BMP stimulus	Alpi	IDA		Mouse	PMID:21324897
Biological Process	GO:0016311	dephosphorylation	Alpi	IDA		Rat	PMID:24076154|RGD:8553411
Biological Process	GO:0006793	phosphorus metabolic process	Alpi	IDA		Rat	PMID:15885097|RGD:2300084
Biological Process	GO:0006793	phosphorus metabolic process	Alpi	IDA		Rat	PMID:7744844|RGD:2300082

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern