Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ALPK2
  • Mouse genes Alpk2
  • Rat genes Alpk2
  • Zfish genes alpk2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Alpk2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Cellular Component	GO:0016323	basolateral plasma membrane	ALPK2	IMP		Human	PMID:28668886
Biological Process	GO:0055013	cardiac muscle cell development	ALPK2	IMP		Human	PMID:29888752
Biological Process	GO:0055013	cardiac muscle cell development	alpk2	IMP	ZFIN:ZDB-MRPHLNO-181004-3	Zfish	PMID:29888752
Biological Process	GO:1905223	epicardium morphogenesis	ALPK2	IMP		Human	PMID:29888752
Biological Process	GO:1905223	epicardium morphogenesis	alpk2	IMP	ZFIN:ZDB-MRPHLNO-181004-2,ZFIN:ZDB-MRPHLNO-181004-3	Zfish	PMID:29888752
Biological Process	GO:0030010	establishment of cell polarity	ALPK2	IMP		Human	PMID:28668886
Biological Process	GO:0060047	heart contraction	alpk2	IMP	ZFIN:ZDB-GENO-181010-2	Zfish	PMID:29888752
Biological Process	GO:0060047	heart contraction	alpk2	IMP	ZFIN:ZDB-MRPHLNO-181004-2,ZFIN:ZDB-MRPHLNO-181004-3	Zfish	PMID:29888752
Biological Process	GO:0003007	heart morphogenesis	ALPK2	IMP		Human	PMID:29888752
Biological Process	GO:0003007	heart morphogenesis	alpk2	IMP	ZFIN:ZDB-GENO-181010-2	Zfish	PMID:29888752
Biological Process	GO:0003007	heart morphogenesis	alpk2	IMP	ZFIN:ZDB-MRPHLNO-181004-3	Zfish	PMID:29888752
Biological Process	GO:0003007	heart morphogenesis	alpk2	IMP	ZFIN:ZDB-MRPHLNO-181004-2	Zfish	PMID:29888752
Biological Process	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development	ALPK2	IMP		Human	PMID:29888752
Biological Process	GO:0042981	regulation of apoptotic process	ALPK2	IMP		Human	PMID:22641666
Biological Process	GO:0010468	regulation of gene expression	ALPK2	IMP		Human	PMID:22641666

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern