Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AMIGO2
  • Mouse genes Amigo2
  • Rat genes Amigo2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Amigo2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	AMIGO2	IPI	UniProtKB:O00555	Human	PMID:21078624
Molecular Function	GO:0005515	protein binding	AMIGO2	IPI	UniProtKB:Q6PL24	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Amigo2	IPI	RGD:1303079|RGD:631413	Rat	PMID:12629050|RGD:634626
Molecular Function	GO:0005515	protein binding	Amigo2	IPI	UniProtKB:Q7TNJ4	Rat	PMID:12843293|RGD:1299593
Molecular Function	GO:0005515	protein binding	Amigo2	IPI	UniProtKB:Q80ZD5	Rat	PMID:12843293|RGD:1299593
Molecular Function	GO:0005515	protein binding	Amigo2	IPI	UniProtKB:Q80ZD7	Rat	PMID:12843293|RGD:1299593
Cellular Component	GO:0005634	nucleus	Amigo2	IDA		Rat	PMID:12843293|RGD:1299593
Cellular Component	GO:0005886	plasma membrane	Amigo2	IDA		Rat	PMID:12843293|RGD:1299593
Biological Process	GO:0021549	cerebellum development	Amigo2	IEP		Rat	PMID:12843293|RGD:1299593
Biological Process	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	Amigo2	IPI	UniProtKB:Q80ZD5	Rat	PMID:12629050|RGD:634626
Biological Process	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	Amigo2	IPI	UniProtKB:Q80ZD7	Rat	PMID:12629050|RGD:634626
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	Amigo2	IPI	UniProtKB:Q7TNJ4	Rat	PMID:12629050|RGD:634626
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Amigo2	IMP		Rat	PMID:12843293|RGD:1299593
Biological Process	GO:0043069	negative regulation of programmed cell death	Amigo2	IDA		Rat	PMID:12843293|RGD:1299593
Biological Process	GO:0051965	positive regulation of synapse assembly	Amigo2	IDA		Mouse	PMID:24613359

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern