Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AMOTL2
  • Mouse genes Amotl2
  • Rat genes Amotl2
  • Zfish genes amotl2a,amotl2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Amotl2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Amotl2	IDA		Mouse	PMID:16019084
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:O14777	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q96A72	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:P46937	Human	PMID:21187284
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:O75771	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q16649	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:P17980	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:P0DOE7	Human	PMID:25556234
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:O75771	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:A0A0S2Z6H0	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q8N5A5-2	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:O14777	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:O14777	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:O75771	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:P46439	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q5VTR2	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q8TEC5	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:A0A1B0GWI1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:A2BDD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:O60941-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:O75150	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:O75771	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:O76064	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:O94964-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:P04264	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:P07947	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:P10827	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:P17980	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:P35240-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:P46439	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:P54646	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:P55081	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q03252	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q05516	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q13515	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q13895	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q15014	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q15311	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q15560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q16543	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q16649	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q2TAC2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q3SY00	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q4G0R1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q5PSV4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q5VTR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q86YD7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q86YV0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q8IYY4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q8N715	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q8TAP4-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q8TD31-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q8TEC5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q969G3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q969R5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q96A72	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q96RD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q99633	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q9BW66	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q9H257-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q9HAQ2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q9UER7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q9ULV0-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AMOTL2	IPI	UniProtKB:Q9Y5B8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Amotl2	IPI	PR:Q8JZS0	Mouse	PMID:18824598
Molecular Function	GO:0005515	protein binding	Amotl2	IPI	PR:Q63ZW7	Mouse	PMID:17397395
Molecular Function	GO:0005515	protein binding	Amotl2	IPI	PR:Q8VBX6	Mouse	PMID:18824598
Molecular Function	GO:0005515	protein binding	Amotl2	IPI	PR:Q6RHR9	Mouse	PMID:16019084
Molecular Function	GO:0005515	protein binding	Amotl2	IPI	PR:Q66T02	Mouse	PMID:18824598
Molecular Function	GO:0005515	protein binding	Amotl2	IPI	PR:Q8VBX6	Mouse	PMID:17397395
Molecular Function	GO:0005515	protein binding	Amotl2	IPI	PR:Q9JLB2	Mouse	PMID:18824598
Molecular Function	GO:0005515	protein binding	amotl2a	IPI	ZFIN:ZDB-GENE-061103-493	Zfish	PMID:17293535
Cellular Component	GO:0016324	apical plasma membrane	Amotl2	IDA		Mouse	PMID:17397395
Cellular Component	GO:0005923	bicellular tight junction	Amotl2	IDA		Mouse	PMID:16019084
Cellular Component	GO:0005923	bicellular tight junction	Amotl2	IDA		Mouse	PMID:17397395
Cellular Component	GO:0005938	cell cortex	amotl2a	IDA		Zfish	PMID:17293535
Cellular Component	GO:0030054	cell junction	amotl2a	IDA		Zfish	PMID:28842668
Cellular Component	GO:0005911	cell-cell junction	amotl2a	IDA		Zfish	PMID:28790366
Cellular Component	GO:0031410	cytoplasmic vesicle	Amotl2	IDA		Mouse	PMID:17397395
Cellular Component	GO:0099513	polymeric cytoskeletal fiber	amotl2a	IDA		Zfish	PMID:28842668
Biological Process	GO:0030036	actin cytoskeleton organization	amotl2a	IGI	ZFIN:ZDB-MRPHLNO-070530-2,ZFIN:ZDB-MRPHLNO-151216-3	Zfish	PMID:28842668
Biological Process	GO:0030036	actin cytoskeleton organization	amotl2b	IGI	ZFIN:ZDB-MRPHLNO-070530-2,ZFIN:ZDB-MRPHLNO-151216-3	Zfish	PMID:28842668
Biological Process	GO:0001525	angiogenesis	amotl2a	IMP	ZFIN:ZDB-MRPHLNO-070530-2	Zfish	PMID:21937427
Biological Process	GO:0016477	cell migration	amotl2a	IMP	ZFIN:ZDB-MRPHLNO-070530-2	Zfish	PMID:17293535
Biological Process	GO:0060026	convergent extension	amotl2a	IMP	ZFIN:ZDB-MRPHLNO-070530-2	Zfish	PMID:17293535
Biological Process	GO:0030866	cortical actin cytoskeleton organization	amotl2a	IMP	ZFIN:ZDB-MRPHLNO-070530-2	Zfish	PMID:17293535
Biological Process	GO:0035907	dorsal aorta development	amotl2a	IGI	ZFIN:ZDB-MRPHLNO-070530-2,ZFIN:ZDB-MRPHLNO-151216-3	Zfish	PMID:28790366
Biological Process	GO:0035907	dorsal aorta development	amotl2b	IGI	ZFIN:ZDB-MRPHLNO-070530-2,ZFIN:ZDB-MRPHLNO-151216-3	Zfish	PMID:28790366
Biological Process	GO:0035912	dorsal aorta morphogenesis	amotl2a	IMP	ZFIN:ZDB-MRPHLNO-070530-2	Zfish	PMID:24806444
Biological Process	GO:0035912	dorsal aorta morphogenesis	amotl2a	IGI	ZFIN:ZDB-MRPHLNO-070530-2,ZFIN:ZDB-MRPHLNO-151216-3	Zfish	PMID:24806444
Biological Process	GO:0035912	dorsal aorta morphogenesis	amotl2b	IGI	ZFIN:ZDB-MRPHLNO-070530-2,ZFIN:ZDB-MRPHLNO-151216-3	Zfish	PMID:24806444
Biological Process	GO:0035912	dorsal aorta morphogenesis	amotl2b	IMP	ZFIN:ZDB-MRPHLNO-151216-3	Zfish	PMID:24806444
Biological Process	GO:0009880	embryonic pattern specification	amotl2a	IMP	ZFIN:ZDB-MRPHLNO-070530-2	Zfish	PMID:17293535
Biological Process	GO:0001935	endothelial cell proliferation	amotl2a	IMP	ZFIN:ZDB-MRPHLNO-070530-2	Zfish	PMID:21937427
Biological Process	GO:0051649	establishment of localization in cell	amotl2a	IGI	ZFIN:ZDB-GENE-061103-493	Zfish	PMID:17293535
Biological Process	GO:0046847	filopodium assembly	amotl2a	IMP	ZFIN:ZDB-MRPHLNO-070530-2	Zfish	PMID:17293535
Biological Process	GO:0008360	regulation of cell shape	amotl2a	IGI	ZFIN:ZDB-MRPHLNO-070530-2,ZFIN:ZDB-MRPHLNO-151216-3	Zfish	PMID:28842668
Biological Process	GO:0008360	regulation of cell shape	amotl2b	IGI	ZFIN:ZDB-MRPHLNO-070530-2,ZFIN:ZDB-MRPHLNO-151216-3	Zfish	PMID:28842668

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern