Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AMY1A,AMY1B,AMY1C,AMY2A,AMY2B
  • Mouse genes Amy1
  • Rat genes Amy1
  • Zfish genes amy2a,amy2al1,amy2al2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Amy1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004556	alpha-amylase activity	AMY2A	IDA		Human	PMID:10769135
Molecular Function	GO:0004556	alpha-amylase activity	AMY1B	IDA		Human	PMID:12527308
Molecular Function	GO:0004556	alpha-amylase activity	AMY1C	IDA		Human	PMID:12527308
Molecular Function	GO:0004556	alpha-amylase activity	AMY1A	IDA		Human	PMID:12527308
Molecular Function	GO:0016160	amylase activity	Amy1	IDA		Mouse	PMID:6163812
Molecular Function	GO:0005509	calcium ion binding	AMY2A	IDA		Human	PMID:10769135
Molecular Function	GO:0005509	calcium ion binding	AMY1B	IDA		Human	PMID:12527308
Molecular Function	GO:0005509	calcium ion binding	AMY1B	IDA		Human	PMID:15299664
Molecular Function	GO:0005509	calcium ion binding	AMY1C	IDA		Human	PMID:12527308
Molecular Function	GO:0005509	calcium ion binding	AMY1C	IDA		Human	PMID:15299664
Molecular Function	GO:0005509	calcium ion binding	AMY1A	IDA		Human	PMID:12527308
Molecular Function	GO:0005509	calcium ion binding	AMY1A	IDA		Human	PMID:15299664
Molecular Function	GO:0031404	chloride ion binding	AMY2A	IDA		Human	PMID:10769135
Molecular Function	GO:0031404	chloride ion binding	AMY1B	IDA		Human	PMID:12527308
Molecular Function	GO:0031404	chloride ion binding	AMY1B	IDA		Human	PMID:15299664
Molecular Function	GO:0031404	chloride ion binding	AMY1C	IDA		Human	PMID:12527308
Molecular Function	GO:0031404	chloride ion binding	AMY1C	IDA		Human	PMID:15299664
Molecular Function	GO:0031404	chloride ion binding	AMY1A	IDA		Human	PMID:12527308
Molecular Function	GO:0031404	chloride ion binding	AMY1A	IDA		Human	PMID:15299664
Cellular Component	GO:0070062	extracellular exosome	AMY2A	HDA		Human	PMID:23533145
Cellular Component	GO:0070062	extracellular exosome	AMY1B	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	AMY1B	HDA		Human	PMID:23533145
Cellular Component	GO:0070062	extracellular exosome	AMY1C	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	AMY1C	HDA		Human	PMID:23533145
Cellular Component	GO:0070062	extracellular exosome	AMY1A	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	AMY1A	HDA		Human	PMID:23533145
Cellular Component	GO:0070062	extracellular exosome	AMY2B	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	AMY2A	IDA		Human	PMID:10769135
Cellular Component	GO:0005615	extracellular space	AMY1B	IDA		Human	PMID:15299664
Cellular Component	GO:0005615	extracellular space	AMY1B	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	AMY1C	IDA		Human	PMID:15299664
Cellular Component	GO:0005615	extracellular space	AMY1C	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	AMY1A	IDA		Human	PMID:15299664
Cellular Component	GO:0005615	extracellular space	AMY1A	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	AMY1A	IDA		Human	PMID:24248522
Cellular Component	GO:0005615	extracellular space	Amy1	IDA		Mouse	PMID:6163812
Cellular Component	GO:0005615	extracellular space	Amy1	IDA		Rat	PMID:12851717|RGD:1304402
Biological Process	GO:0016052	carbohydrate catabolic process	AMY2A	IDA		Human	PMID:10769135
Biological Process	GO:0005975	carbohydrate metabolic process	Amy1	IEP		Rat	PMID:12851717|RGD:1304402
Biological Process	GO:0071391	cellular response to estrogen stimulus	amy2al1	IDA		Zfish	PMID:18618001
Biological Process	GO:0009311	oligosaccharide metabolic process	AMY1B	IDA		Human	PMID:12527308
Biological Process	GO:0009311	oligosaccharide metabolic process	AMY1C	IDA		Human	PMID:12527308
Biological Process	GO:0009311	oligosaccharide metabolic process	AMY1A	IDA		Human	PMID:12527308
Biological Process	GO:0009617	response to bacterium	Amy1	IEP		Mouse	PMID:23012479

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern