Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ANGPT4
  • Mouse genes Angpt4
  • Rat genes Angpt4
  • Zfish genes angpt4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Angpt4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030971	receptor tyrosine kinase binding	ANGPT4	IDA		Human	PMID:10051567
Molecular Function	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	ANGPT4	IDA		Human	PMID:10051567
Molecular Function	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	ANGPT4	IDA		Human	PMID:15851516
Cellular Component	GO:0005615	extracellular space	ANGPT4	IDA		Human	PMID:10025962
Biological Process	GO:0071456	cellular response to hypoxia	ANGPT4	IEP		Human	PMID:12958144
Biological Process	GO:0016525	negative regulation of angiogenesis	ANGPT4	IDA		Human	PMID:16790085
Biological Process	GO:0043066	negative regulation of apoptotic process	ANGPT4	IDA		Human	PMID:12958144
Biological Process	GO:0043066	negative regulation of apoptotic process	ANGPT4	IDA		Human	PMID:15284220
Biological Process	GO:0043537	negative regulation of blood vessel endothelial cell migration	ANGPT4	IDA		Human	PMID:16790085
Biological Process	GO:0007219	Notch signaling pathway	Angpt4	IDA		Mouse	PMID:23117660
Biological Process	GO:0045766	positive regulation of angiogenesis	ANGPT4	IDA		Human	PMID:15284220
Biological Process	GO:0043536	positive regulation of blood vessel endothelial cell migration	ANGPT4	IDA		Human	PMID:15284220
Biological Process	GO:0010595	positive regulation of endothelial cell migration	ANGPT4	IDA		Human	PMID:12958144
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	ANGPT4	IDA		Human	PMID:15851516

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern