Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ANGPTL4
  • Mouse genes Angptl4
  • Rat genes Angptl4
  • Zfish genes angptl4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Angptl4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004857	enzyme inhibitor activity	Angptl4	IDA		Mouse	MGI:MGI:3687912|PMID:12401877
Molecular Function	GO:0042802	identical protein binding	ANGPTL4	IPI	UniProtKB:Q9BY76	Human	PMID:19028676
Molecular Function	GO:0042802	identical protein binding	Angptl4	IPI	RGD:735058	Rat	PMID:14570927|RGD:1302799
Molecular Function	GO:0042802	identical protein binding	Angptl4	IPI	RGD:735058	Rat	PMID:15863837|RGD:1578348
Molecular Function	GO:0005515	protein binding	ANGPTL4	IPI	UniProtKB:P05556	Human	PMID:21397862
Molecular Function	GO:0005515	protein binding	ANGPTL4	IPI	UniProtKB:P18084	Human	PMID:21397862
Cellular Component	GO:0072562	blood microparticle	ANGPTL4	HDA		Human	PMID:22516433
Cellular Component	GO:0005576	extracellular region	ANGPTL4	IDA		Human	PMID:10698685
Cellular Component	GO:0005576	extracellular region	Angptl4	IDA		Mouse	MGI:MGI:1354423|PMID:10698685
Cellular Component	GO:0005615	extracellular space	ANGPTL4	IDA		Human	PMID:10698685
Cellular Component	GO:0005615	extracellular space	Angptl4	IDA		Mouse	PMID:10866690
Biological Process	GO:1902262	apoptotic process involved in blood vessel morphogenesis	angptl4	IMP	ZFIN:ZDB-MRPHLNO-170306-2	Zfish	PMID:27834691
Biological Process	GO:0072577	endothelial cell apoptotic process	Angptl4	IDA		Mouse	PMID:10698685
Biological Process	GO:0043066	negative regulation of apoptotic process	ANGPTL4	IDA		Human	PMID:10698685
Biological Process	GO:0043066	negative regulation of apoptotic process	Angptl4	IDA		Mouse	MGI:MGI:1354423|PMID:10698685
Biological Process	GO:2000352	negative regulation of endothelial cell apoptotic process	Angptl4	IDA		Mouse	PMID:10698685
Biological Process	GO:0051005	negative regulation of lipoprotein lipase activity	ANGPTL4	IDA		Human	PMID:19542565
Biological Process	GO:0051005	negative regulation of lipoprotein lipase activity	ANGPTL4	IDA		Human	PMID:29899144
Biological Process	GO:0051005	negative regulation of lipoprotein lipase activity	Angptl4	IDA		Mouse	MGI:MGI:3687912|PMID:12401877
Biological Process	GO:0043335	protein unfolding	ANGPTL4	IDA		Human	PMID:29899144
Biological Process	GO:0009617	response to bacterium	angptl4	IDA		Zfish	PMID:17055441
Biological Process	GO:0001666	response to hypoxia	Angptl4	IEP		Rat	PMID:17033689|RGD:1625355
Biological Process	GO:0070328	triglyceride homeostasis	Angptl4	IMP		Mouse	MGI:MGI:4412214|PMID:19542565

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern