Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ANGPTL8
  • Mouse genes Angptl8
  • Rat genes Angptl8
  • Zfish genes angptl8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Angptl8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ANGPTL8	IPI	UniProtKB:Q96PM5	Human	PMID:21988832
Cellular Component	GO:0005576	extracellular region	ANGPTL8	IDA		Human	PMID:23150577
Biological Process	GO:0048469	cell maturation	Angptl8	IMP		Mouse	PMID:22569073
Biological Process	GO:0044255	cellular lipid metabolic process	Angptl8	IMP		Mouse	MGI:MGI:5440843|PMID:22809513
Biological Process	GO:0044255	cellular lipid metabolic process	Angptl8	IMP		Mouse	MGI:MGI:5613455|PMID:24043787
Biological Process	GO:0045444	fat cell differentiation	Angptl8	IMP		Mouse	MGI:MGI:5613455|PMID:24043787
Biological Process	GO:0045444	fat cell differentiation	Angptl8	IMP		Mouse	PMID:22569073
Biological Process	GO:0010954	positive regulation of protein processing	ANGPTL8	IDA		Human	PMID:23150577
Biological Process	GO:0019216	regulation of lipid metabolic process	ANGPTL8	IDA		Human	PMID:25417115
Biological Process	GO:0019216	regulation of lipid metabolic process	Angptl8	IMP		Mouse	MGI:MGI:5613455|PMID:24043787
Biological Process	GO:0019216	regulation of lipid metabolic process	Angptl8	IMP		Mouse	PMID:22569073
Biological Process	GO:0050746	regulation of lipoprotein metabolic process	ANGPTL8	IMP		Human	PMID:23150577
Biological Process	GO:0050746	regulation of lipoprotein metabolic process	Angptl8	IMP		Mouse	MGI:MGI:5613455|PMID:24043787
Biological Process	GO:0070328	triglyceride homeostasis	ANGPTL8	IGI	UniProtKB:Q9Y5C1	Human	PMID:23150577
Biological Process	GO:0070328	triglyceride homeostasis	ANGPTL8	IDA		Human	PMID:25417115
Biological Process	GO:0070328	triglyceride homeostasis	Angptl8	IMP		Mouse	MGI:MGI:5613455|PMID:24043787
Biological Process	GO:0070328	triglyceride homeostasis	Angptl8	IMP		Mouse	MGI:MGI:5440843|PMID:22809513

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern