Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ANKH
  • Mouse genes Ank
  • Rat genes Ankh
  • Zfish genes ankha,ankhb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ank

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030504	inorganic diphosphate transmembrane transporter activity	ANKH	IDA		Human	PMID:11326272
Molecular Function	GO:0030504	inorganic diphosphate transmembrane transporter activity	Ank	IDA		Mouse	MGI:MGI:1860991|PMID:10894769
Molecular Function	GO:0005315	inorganic phosphate transmembrane transporter activity	ANKH	IDA		Human	PMID:11326272
Cellular Component	GO:0005576	extracellular region	Ank	IMP	MGI:MGI:2385534	Mouse	PMID:12817751
Cellular Component	GO:0016020	membrane	ANKH	IDA		Human	PMID:11326272
Cellular Component	GO:0016020	membrane	Ank	IDA		Mouse	MGI:MGI:1934084|PMID:11326272
Cellular Component	GO:0005886	plasma membrane	Ank	IDA		Mouse	PMID:10894769
Biological Process	GO:0030282	bone mineralization	Ank	IMP	MGI:MGI:2385534	Mouse	PMID:12817751
Biological Process	GO:0030282	bone mineralization	Ank	IMP	MGI:MGI:1856651	Mouse	PMID:12817751
Biological Process	GO:0030282	bone mineralization	Ank	IDA		Mouse	PMID:12817751
Biological Process	GO:0055074	calcium ion homeostasis	Ank	IMP	MGI:MGI:2385534	Mouse	PMID:12817751
Biological Process	GO:0055074	calcium ion homeostasis	Ank	IMP	MGI:MGI:1856651	Mouse	PMID:12817751
Biological Process	GO:0055074	calcium ion homeostasis	Ank	IMP	MGI:MGI:1856651	Mouse	PMID:21490328
Biological Process	GO:0071529	cementum mineralization	Ank	IDA		Mouse	PMID:31059863
Biological Process	GO:0071529	cementum mineralization	Ank	IMP	MGI:MGI:3785162	Mouse	PMID:31059863
Biological Process	GO:0071529	cementum mineralization	Ank	IMP		Mouse	PMID:31059863
Biological Process	GO:0071529	cementum mineralization	Ank	IMP	MGI:MGI:3608932	Mouse	PMID:31059863
Biological Process	GO:0071344	diphosphate metabolic process	Ank	IMP		Mouse	PMID:31059863
Biological Process	GO:0071344	diphosphate metabolic process	Ank	IDA		Mouse	PMID:31059863
Biological Process	GO:0010467	gene expression	Ank	IMP	MGI:MGI:1856651	Mouse	PMID:12817751
Biological Process	GO:0010467	gene expression	Ank	IDA		Mouse	PMID:31059863
Biological Process	GO:0010467	gene expression	Ank	IMP	MGI:MGI:1856651	Mouse	PMID:15625282
Biological Process	GO:0010467	gene expression	Ank	IMP		Mouse	PMID:31059863
Biological Process	GO:0140928	inhibition of non-skeletal tissue mineralization	Ank	IMP	MGI:MGI:2385534	Mouse	PMID:21490328
Biological Process	GO:0140928	inhibition of non-skeletal tissue mineralization	Ank	IMP	MGI:MGI:1856651	Mouse	PMID:15625282
Biological Process	GO:0140928	inhibition of non-skeletal tissue mineralization	Ank	IDA		Mouse	PMID:21490328
Biological Process	GO:0140928	inhibition of non-skeletal tissue mineralization	Ank	IMP	MGI:MGI:1856651	Mouse	PMID:21490328
Biological Process	GO:0030505	inorganic diphosphate transport	Ank	IMP	MGI:MGI:1856651	Mouse	PMID:15625282
Biological Process	GO:0046716	muscle cell cellular homeostasis	Ank	IMP	MGI:MGI:1856651	Mouse	PMID:15625282
Biological Process	GO:0055062	phosphate ion homeostasis	Ank	IMP	MGI:MGI:1856651	Mouse	PMID:12817751
Biological Process	GO:0030500	regulation of bone mineralization	Ank	IMP	MGI:MGI:1856651	Mouse	PMID:7276519
Biological Process	GO:0030500	regulation of bone mineralization	Ank	IMP	MGI:MGI:1856651	Mouse	PMID:10894769
Biological Process	GO:1904383	response to sodium phosphate	Ank	IMP	MGI:MGI:2385534	Mouse	PMID:12817751

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern