Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ANK1
  • Mouse genes Ank1
  • Rat genes Ank1
  • Zfish genes ank1a,ank1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ank1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051117	ATPase binding	ANK1	IPI	UniProtKB:P06685	Human	PMID:8159688
Molecular Function	GO:0008093	cytoskeletal anchor activity	ANK1	IDA		Human	PMID:379653
Molecular Function	GO:0019899	enzyme binding	ANK1	IPI	UniProtKB:Q9NWT6	Human	PMID:21177872
Molecular Function	GO:0005515	protein binding	ANK1	IPI	UniProtKB:Q02094	Human	PMID:12719424
Molecular Function	GO:0005515	protein binding	ANK1	IPI	UniProtKB:Q02094	Human	PMID:16580865
Molecular Function	GO:0005515	protein binding	ANK1	IPI	UniProtKB:Q5VST9-3	Human	PMID:16962094
Molecular Function	GO:0005515	protein binding	ANK1	IPI	UniProtKB:P02730	Human	PMID:379653
Molecular Function	GO:0005515	protein binding	Ank1	IPI	PR:P04919	Mouse	PMID:17715300
Molecular Function	GO:0005515	protein binding	Ank1	IPI	RGD:631335	Rat	PMID:12631729|RGD:633514
Molecular Function	GO:0019903	protein phosphatase binding	ANK1	IPI	UniProtKB:P08575	Human	PMID:12354383
Molecular Function	GO:0030507	spectrin binding	ANK1	IDA		Human	PMID:12354383
Molecular Function	GO:0030507	spectrin binding	ANK1	IDA		Human	PMID:379653
Molecular Function	GO:0030507	spectrin binding	ANK1	IPI	UniProtKB:P11277	Human	PMID:8159688
Cellular Component	GO:0031672	A band	Ank1	IDA		Rat	PMID:9664041|RGD:631996
Cellular Component	GO:0030673	axolemma	Ank1	IDA		Rat	PMID:2139035|RGD:1599113
Cellular Component	GO:0030863	cortical cytoskeleton	Ank1	IDA		Mouse	PMID:18723693
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	ANK1	IDA		Human	PMID:12354383
Cellular Component	GO:0031430	M band	Ank1	IDA		Rat	PMID:12631729|RGD:633514
Cellular Component	GO:0031430	M band	Ank1	IDA		Rat	PMID:17012262|RGD:6767299
Cellular Component	GO:0031430	M band	Ank1	IDA		Rat	PMID:9024692|RGD:11251703
Cellular Component	GO:0016020	membrane	Ank1	IDA		Mouse	PMID:18723693
Cellular Component	GO:0043005	neuron projection	Ank1	IDA		Rat	PMID:9202331|RGD:1599109
Cellular Component	GO:0005634	nucleus	Ank1	IDA		Rat	PMID:9024692|RGD:11251703
Cellular Component	GO:0005634	nucleus	Ank1	IDA		Rat	PMID:9378703|RGD:1599110
Cellular Component	GO:0005886	plasma membrane	ANK1	IDA		Human	PMID:379653
Cellular Component	GO:0005886	plasma membrane	Ank1	IDA		Rat	PMID:9202331|RGD:1599109
Cellular Component	GO:0045211	postsynaptic membrane	Ank1	IDA		Rat	PMID:9664041|RGD:631996
Cellular Component	GO:0042383	sarcolemma	Ank1	IDA		Rat	PMID:9024692|RGD:11251703
Cellular Component	GO:0042383	sarcolemma	Ank1	IDA		Rat	PMID:9664041|RGD:631996
Cellular Component	GO:0016529	sarcoplasmic reticulum	Ank1	IDA		Rat	PMID:12631729|RGD:633514
Cellular Component	GO:0016529	sarcoplasmic reticulum	Ank1	IDA		Rat	PMID:9024692|RGD:11251703
Cellular Component	GO:0014731	spectrin-associated cytoskeleton	ANK1	IDA		Human	PMID:379653
Cellular Component	GO:0014731	spectrin-associated cytoskeleton	Ank1	IMP	MGI:MGI:1856298	Mouse	PMID:6234993
Cellular Component	GO:0030018	Z disc	Ank1	IDA		Rat	PMID:12631729|RGD:633514
Cellular Component	GO:0030018	Z disc	Ank1	IDA		Rat	PMID:9024692|RGD:11251703
Biological Process	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	ANK1	IDA		Human	PMID:18768923
Biological Process	GO:0048821	erythrocyte development	Ank1	IMP	MGI:MGI:5502651	Mouse	PMID:23390527
Biological Process	GO:0048821	erythrocyte development	Ank1	IMP	MGI:MGI:1856298	Mouse	PMID:2139228
Biological Process	GO:0098662	inorganic cation transmembrane transport	Ank1	IMP	MGI:MGI:1856298	Mouse	PMID:7492791
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	Ank1	IMP	MGI:MGI:5502651	Mouse	PMID:23390527
Biological Process	GO:0006779	porphyrin-containing compound biosynthetic process	Ank1	IMP	MGI:MGI:1856298	Mouse	PMID:658175
Biological Process	GO:0010638	positive regulation of organelle organization	Ank1	IMP		Rat	PMID:22045734|RGD:6766380
Biological Process	GO:0072659	protein localization to plasma membrane	ANK1	IMP		Human	PMID:18768923

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern