Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ANKLE2
  • Mouse genes Ankle2
  • Rat genes Ankle2
  • Zfish genes ankle2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ankle2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ANKLE2	IPI	UniProtKB:O75531	Human	PMID:22770216
Molecular Function	GO:0005515	protein binding	ANKLE2	IPI	UniProtKB:Q19848	Human	PMID:22770216
Molecular Function	GO:0051721	protein phosphatase 2A binding	ANKLE2	IDA		Human	PMID:22770216
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ANKLE2	IDA		Human	PMID:22770216
Cellular Component	GO:0016020	membrane	ANKLE2	HDA		Human	PMID:19946888
Biological Process	GO:0007417	central nervous system development	ANKLE2	IDA		Human	PMID:25259927
Biological Process	GO:0007084	mitotic nuclear membrane reassembly	ANKLE2	IMP		Human	PMID:22770216
Biological Process	GO:0043066	negative regulation of apoptotic process	ANKLE2	IDA		Human	PMID:25259927
Biological Process	GO:0042326	negative regulation of phosphorylation	ANKLE2	IDA		Human	PMID:22770216
Biological Process	GO:0035307	positive regulation of protein dephosphorylation	ANKLE2	IDA		Human	PMID:22770216

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern