Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ANKRD2
  • Mouse genes Ankrd2
  • Rat genes Ankrd2
  • Zfish genes ankrd2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ankrd2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Ankrd2	IDA		Mouse	PMID:24434510
Molecular Function	GO:0005515	protein binding	ANKRD2	IPI	UniProtKB:Q16659	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ankrd2	IPI	UniProtKB:P41133	Mouse	MGI:MGI:5527051|PMID:23824195
Molecular Function	GO:0043422	protein kinase B binding	ANKRD2	IPI	UniProtKB:P31751	Human	PMID:21737686
Molecular Function	GO:0043422	protein kinase B binding	Ankrd2	IPI	UniProtKB:Q60823	Mouse	MGI:MGI:5317372|PMID:21737686
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ANKRD2	IDA		Human	PMID:24434510
Molecular Function	GO:0031432	titin binding	Ankrd2	IPI	UniProtKB:A2ASS6	Mouse	MGI:MGI:3801259|PMID:18310072
Cellular Component	GO:0005829	cytosol	ANKRD2	IDA		Human	PMID:21737686
Cellular Component	GO:0005829	cytosol	Ankrd2	IDA		Mouse	MGI:MGI:5317372|PMID:21737686
Cellular Component	GO:0000791	euchromatin	Ankrd2	IDA		Mouse	MGI:MGI:5543771|PMID:17926058
Cellular Component	GO:0031674	I band	Ankrd2	IDA		Mouse	MGI:MGI:5543771|PMID:17926058
Cellular Component	GO:0031674	I band	Ankrd2	IDA		Mouse	PMID:14741210
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ANKRD2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030016	myofibril	Ankrd2	IDA		Mouse	MGI:MGI:3801259|PMID:18310072
Cellular Component	GO:0005634	nucleus	ANKRD2	IDA		Human	PMID:21737686
Cellular Component	GO:0005634	nucleus	Ankrd2	IDA		Mouse	MGI:MGI:5317372|PMID:21737686
Cellular Component	GO:0005634	nucleus	Ankrd2	IDA		Mouse	PMID:18302940
Cellular Component	GO:0016605	PML body	Ankrd2	IDA		Mouse	PMID:24434510
Cellular Component	GO:0030017	sarcomere	Ankrd2	IDA		Mouse	PMID:12004005
Cellular Component	GO:0016528	sarcoplasm	Ankrd2	IDA		Mouse	PMID:24434510
Cellular Component	GO:0016528	sarcoplasm	Ankrd2	IDA		Mouse	PMID:18302940
Biological Process	GO:0014902	myotube differentiation	Ankrd2	IDA		Mouse	PMID:18302940
Biological Process	GO:0014902	myotube differentiation	Ankrd2	IMP		Mouse	PMID:23824195
Biological Process	GO:0045662	negative regulation of myoblast differentiation	ANKRD2	IMP		Human	PMID:21737686
Biological Process	GO:0045662	negative regulation of myoblast differentiation	Ankrd2	IMP		Mouse	MGI:MGI:5527051|PMID:23824195
Biological Process	GO:0045662	negative regulation of myoblast differentiation	Ankrd2	IMP		Mouse	MGI:MGI:5317372|PMID:21737686
Biological Process	GO:0010832	negative regulation of myotube differentiation	Ankrd2	IDA		Mouse	PMID:18302940
Biological Process	GO:0010832	negative regulation of myotube differentiation	Ankrd2	IMP		Mouse	PMID:23824195
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ANKRD2	IGI	UniProtKB:P19838	Human	PMID:24434510
Biological Process	GO:0001817	regulation of cytokine production	Ankrd2	IMP		Mouse	PMID:24434510
Biological Process	GO:1902253	regulation of intrinsic apoptotic signaling pathway by p53 class mediator	Ankrd2	IDA		Mouse	PMID:18302940
Biological Process	GO:1902253	regulation of intrinsic apoptotic signaling pathway by p53 class mediator	Ankrd2	IMP		Mouse	PMID:18302940
Biological Process	GO:2000291	regulation of myoblast proliferation	Ankrd2	IMP		Mouse	PMID:18302940
Biological Process	GO:2000291	regulation of myoblast proliferation	Ankrd2	IDA		Mouse	PMID:18302940
Biological Process	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	ANKRD2	IDA		Human	PMID:24434510
Biological Process	GO:0035914	skeletal muscle cell differentiation	Ankrd2	IMP		Mouse	PMID:22147266

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern